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Title:
TYROSINASE ACTIVITY CONTROLLING AGENTS, PROCESS FOR PRODUCING THE SAME AND EXTERNAL PREPARATIONS CONTAINING THE SAME
Document Type and Number:
WIPO Patent Application WO/2004/033475
Kind Code:
A1
Abstract:
A tyrosinase activity controlling agent containing, as the active ingredient, a compound having an activity of inhibiting or promoting tyrosinase, an external preparation containing the controlling agent, and a process for producing the above compound.

Inventors:
Tokiwa, Yutaka c/o Tsukuba, Center (NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 1-1-1, Higash, Tsukuba-shi Ibaraki, 305-8561, JP)
Kitagawa, Masaru c/o TOYOBO RESEARCH CENTER CO. LTD. (1-1, Katata 2-chom, Otsu-shi Shiga, 520-0292, JP)
Yoshino, Kenji c/o TOYOBO RESEARCH CENTER CO. LTD. (1-1, Katata 2-chom, Otsu-shi Shiga, 520-0292, JP)
Yanagidani, Shusaku c/o TOYOBO RESEARCH CENTER CO. LTD. (1-1, Katata 2-chom, Otsu-shi Shiga, 520-0292, JP)
Raku, Takao c/o Tsukuba, Center (NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 1-1-1, Higash, Tsukuba-shi Ibaraki, 305-8561, JP)
Totani, Tetsuzo c/o KONAN CHEMICAL INDUSTRY CO. LTD. (5-21, Nakagawa-ch, Takatsuki-shi Osaka, 569-0066, JP)
Shimakawa, Hiromi c/o KONAN CHEMICAL INDUSTRY CO. LTD. (5-21, Nakagawa-ch, Takatsuki-shi Osaka, 569-0066, JP)
Application Number:
PCT/JP2003/013018
Publication Date:
April 22, 2004
Filing Date:
October 10, 2003
Export Citation:
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Assignee:
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (3-1 Kasumigaseki 1-chome, Chiyoda-ku, Tokyo, 100-8921, JP)
TOYO BOSEKI KABUSHIKI KAISHA (2-8 Dojima Hama 2-chome, Kita-ku Osaka-shi, Osaka, 530-8230, JP)
KONAN CHEMICAL INDUSTRY CO., LTD. (5-21, Nakagawa-cho Takatsuki-shi, Osaka, 569-0066, JP)
Tokiwa, Yutaka c/o Tsukuba, Center (NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 1-1-1, Higash, Tsukuba-shi Ibaraki, 305-8561, JP)
Kitagawa, Masaru c/o TOYOBO RESEARCH CENTER CO. LTD. (1-1, Katata 2-chom, Otsu-shi Shiga, 520-0292, JP)
Yoshino, Kenji c/o TOYOBO RESEARCH CENTER CO. LTD. (1-1, Katata 2-chom, Otsu-shi Shiga, 520-0292, JP)
Yanagidani, Shusaku c/o TOYOBO RESEARCH CENTER CO. LTD. (1-1, Katata 2-chom, Otsu-shi Shiga, 520-0292, JP)
Raku, Takao c/o Tsukuba, Center (NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 1-1-1, Higash, Tsukuba-shi Ibaraki, 305-8561, JP)
Totani, Tetsuzo c/o KONAN CHEMICAL INDUSTRY CO. LTD. (5-21, Nakagawa-ch, Takatsuki-shi Osaka, 569-0066, JP)
Shimakawa, Hiromi c/o KONAN CHEMICAL INDUSTRY CO. LTD. (5-21, Nakagawa-ch, Takatsuki-shi Osaka, 569-0066, JP)
International Classes:
A61K8/60; A61K31/201; A61K31/375; A61K31/7024; A61K31/7034; A61P17/00; A61P43/00; A61Q5/08; A61Q19/02; A61Q19/08; C07H13/06; C07H15/203; C12P19/44; C12P19/46; (IPC1-7): C07H15/203; A61K7/00; A61K7/48; A61K31/201; A61K31/375; A61K31/7024; A61K31/7034; A61P17/00; A61P43/00; C07H13/06; C12N9/99; C12P19/00; C12P19/44
Domestic Patent References:
2001-10-25
Foreign References:
US5346693A1994-09-13
US6306376B12001-10-23
JPH05320152A1993-12-03
EP0477927A11992-04-01
JP2002114670A2002-04-16
JPH05137994A1993-06-01
JP2001322990A2001-11-20
JPH05294820A1993-11-09
JPH04182415A1992-06-30
JP2001316226A2001-11-13
JP2002275060A2002-09-25
JP2001158730A2001-06-12
JP2001151623A2001-06-05
ES2141670A12000-03-16
Other References:
NAKAJIMA N. ET AL: 'Lipase-catalyzed direct and regioselective acylation of flavonoid glucoside for mechanistic investigation of stable plant pigments' JOURNAL OF BIOSCIENCE AND BIOENGINEERING vol. 87, no. 1, 1999, pages 105 - 107, XP001015236
VEROTTA L. ET AL: 'Polyphenolic glycosides from african proteaceae' JOURNAL OF NATURAL PRODUCTS vol. 62, no. 11, 1999, pages 1526 - 1531, XP002974843
ISHIHARA KOJI. ET AL: 'A chemoenzymatic synthesis of aromatic carboxylic acid vinyl esters' JOURNAL OF MOLECULAR CATALYSIS B:ENZYMATIC vol. 7, 1999, pages 307 - 310, XP002974844
LILJEBLAD, ARTO. ET AL: 'Enzymatic methods for the preparation of enantiopure malic and aspartic acid derivatives in organic solvents' TETRAHEDRON: ASYMMETRY vol. 10, 1999, pages 4405 - 4415, XP004186386
ARMESTO, NURIA ET AL: 'Regioselective enzymatic acylation of methyl shikimate. Influence of acyl chain length and solvent polarity on enzyme specificity' J. ORG. CHEM. vol. 67, no. 14, 12 June 2002, pages 4978 - 4981, XP002974845
PEDERSEN, NINFA RANGEL, ET AL: 'Efficient transesterification of sucrose catalysed by the metalloprotease thermolysin in dimethylsulfoxide' FEBS LETTERS vol. 519, no. 13, 22 May 2002, pages 181 - 184, XP004356844
See also references of EP 1550667A1
Attorney, Agent or Firm:
Saegusa, Eiji (Kitahama TNK Building, 1-7-1 Doshomachi, Chuo-k, Osaka-shi Osaka, 541-0045, JP)
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