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Title:
TYROSINE KINASE INHIBITOR HAVING LOW IMPURITY CONTENT
Document Type and Number:
WIPO Patent Application WO/2021/037185
Kind Code:
A1
Abstract:
The present disclosure relates to a tyrosine kinase inhibitor having a low impurity content. In particular, the present disclosure relates to a compound as shown in formula I or a pharmaceutically acceptable salt thereof, the impurity content of which being less than 0.2%.

Inventors:
ZHANG QUANLIANG (CN)
QIU ZHENJUN (CN)
CAO YONGXING (CN)
WEI YANLI (CN)
Application Number:
PCT/CN2020/111995
Publication Date:
March 04, 2021
Filing Date:
August 28, 2020
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Assignee:
JIANGSU HENGRUI MEDICINE CO (CN)
International Classes:
C07D401/14; A61K31/4709; A61P35/00
Domestic Patent References:
WO2020083188A12020-04-30
WO2017186140A12017-11-02
WO2012122865A22012-09-20
WO2014008794A12014-01-16
WO2019080830A12019-05-02
Foreign References:
CN110960529A2020-04-07
CN110840892A2020-02-28
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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