Title:
TYROSINE KINASE INHIBITORS
Document Type and Number:
WIPO Patent Application WO2003086315
Kind Code:
A3
Abstract:
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non-receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises a benzazocine moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
Inventors:
TROTTER B WESLEY (US)
Application Number:
PCT/US2003/012457
Publication Date:
January 08, 2004
Filing Date:
April 08, 2003
Export Citation:
Assignee:
MERCK & CO INC (US)
TROTTER B WESLEY (US)
TROTTER B WESLEY (US)
International Classes:
A61K31/138; A61K31/337; A61K31/4465; A61K31/4535; A61K31/498; A61K31/4995; A61K39/395; A61K45/00; A61P3/10; A61P9/00; A61P9/10; A61P15/00; A61P17/06; A61P19/02; A61P19/04; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P37/06; A61P43/00; C07D487/04; C07D487/08; (IPC1-7): A61K31/4995; C07D487/08
Other References:
PARADISI ET AL.: "Stereoselective synthesis of alpha,alpha'-diamino-dicarboxylic acids", TETRAHEDRON ASYMMETRY, vol. 11, 17 November 2000 (2000-11-17), pages 4617 - 4622, XP004227884
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