Title:
UNSATURATED URONIC ACID REDUCTASE AND ALGINIC ACID DERIVATIVE PRODUCTION METHOD
Document Type and Number:
WIPO Patent Application WO/2019/168161
Kind Code:
A1
Abstract:
[Problem] To provide a method and the like for producing 2-keto-3-deoxy-D-gluconate (KDG) efficiently by using an enzyme capable of producing KDG through reduction of 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH). [Solution] This problem is solved by a method for producing KDG by bringing DEH into contact with a polypeptide having an amino acid sequence indicated in SEQ ID NO:2 or a polypeptide that has a DEH-reducing activity and that has an amino acid sequence sharing at least 85% identity with said amino acid sequence.
Inventors:
MIYAKE HIDEO (JP)
SHIBATA TOSHIYUKI (JP)
TANAKA REIJI (JP)
HAMAJI NONOKA (JP)
SHIBATA TOSHIYUKI (JP)
TANAKA REIJI (JP)
HAMAJI NONOKA (JP)
Application Number:
PCT/JP2019/008131
Publication Date:
September 06, 2019
Filing Date:
March 01, 2019
Export Citation:
Assignee:
UNIV MIE (JP)
International Classes:
C12N15/53; C12N9/02; C12N15/63; C12P7/60
Domestic Patent References:
| WO2017175694A1 | 2017-10-12 |
Other References:
INOUE, AKIRA ET AL.: "Identification of a 4-Deoxy- L-erythro-5-hexoseulose Uronic Acid Reductase", FIRED, IN AN ALGINOLYTIC BACTERIUM FLAVOBACTERIUM SP. STRAIN UMI-01 MARINE DRUGS, vol. 13, 2015, pages 493 - 508, XP055362536, doi:10.3390/md13010493
TANAKA, REIJI ET AL.: "Formosa haliotis sp. Nov., a brown-alga-degrading bacterium isolated from the gut of the abalone Haliotis gigantea", INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, vol. 65, no. 12, 2015, pages 4388 - 4393, XP055634413
TANAKA, REIJI ET AL.: "Formosa haliotis sp. Nov., a brown-alga-degrading bacterium isolated from the gut of the abalone Haliotis gigantea", INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, vol. 65, no. 12, 2015, pages 4388 - 4393, XP055634413
Attorney, Agent or Firm:
KOBAYASHI, Youhei (JP)
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