Title:
UPADACITINIB CRYSTAL FORM AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/177645
Kind Code:
A1
Abstract:
Disclosed are a new Upadacitinib crystal form and a preparation method therefor, a pharmaceutical composition containing the crystal form, and use of the crystal form in preparation of JAK inhibitors and drugs for treating rheumatoid arthritis. Compared with the prior art, the new Upadacitinib crystal form has one or more improved characteristics, and is of great value for the optimization and development of drugs in future.
Inventors:
CHEN MINHUA (CN)
SHI JIAMING (CN)
ZHANG JING (CN)
JING HUIZE (CN)
SHI JIAMING (CN)
ZHANG JING (CN)
JING HUIZE (CN)
Application Number:
PCT/CN2020/077327
Publication Date:
September 10, 2020
Filing Date:
February 29, 2020
Export Citation:
Assignee:
CRYSTAL PHARMACEUTICAL SUZHOU CO LTD (CN)
International Classes:
A61K31/4985; C07D487/14; A61P17/00; A61P19/02; C07D417/12
Domestic Patent References:
WO2019016745A1 | 2019-01-24 | |||
WO2015061665A1 | 2015-04-30 |
Foreign References:
CN108368121A | 2018-08-03 | |||
CN109369659A | 2019-02-22 | |||
CN102711476A | 2012-10-03 |
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