UREA DERIVATIVE AND USE THEREOF

Title:

UREA DERIVATIVE AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2017/038870

Kind Code:

A1

Abstract:

The purpose of the present invention is to provide a compound having an inhibition activity against discoidin domain receptor 1. The present invention provides a urea derivative represented by the formula and a pharmacologically acceptable salt thereof.

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Inventors:

TSUTSUI HIDEYUKI (JP)
OKIMURA KEIICHI (JP)
UDAGAWA SYUJI (JP)
KAINO MIE (JP)
MEGURO HIROYUKI (JP)
SEKIYA YUMIKO (JP)

Application Number:

PCT/JP2016/075495

Publication Date:

March 09, 2017

Filing Date:

August 31, 2016

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Assignee:

TORAY INDUSTRIES (JP)

International Classes:

C07C381/00; A61K31/17; A61P35/00; A61P35/04; A61P43/00

Domestic Patent References:

WO2011040509A1

2011-04-07

Foreign References:

CN102319242A	2012-01-18
JP2012211086A	2012-11-01

Other References:

MARYANN T. ROBAK ET AL.: "Enantioselective Aza- Henry Reaction with an N-Sulfinyl Urea Organocatalyst", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 129, no. 49, December 2007 (2007-12-01), pages 15110 - 15111, XP055367780

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