Title:
URIC ACID LEVEL LOWERING AGENT
Document Type and Number:
WIPO Patent Application WO/2015/194034
Kind Code:
A1
Abstract:
Disclosed is a uric acid level lowering agent comprising, as an active ingredient: a tyrosine-containing cyclic dipeptide selected from the group consisting of cyclotryptophanyltyrosine, cycloseryltyrosine, cycloprolyltyrosine, cyclotyrosylglycine, cyclotyrosyltyrosine, cyclophenylalanyltyrosine, cycloleucyltyrosine, cyclolysyltyrosine, cyclohistidyltyrosine, cycloalanyltyrosine, cycloglutamyltyrosine, cyclovalyltyrosine, cycloisoleucyltyrosine, cyclothreonyltyrosine, cycloaspartyltyrosine, cycloasparaginyltyrosine, cycloglutaminyltyrosine, cycloarginyltyrosine, cyclomethionyltyrosine, and cyclotyrosylcysteine; or a salt thereof. This uric acid level lowering agent has an excellent uric acid level lowering effect, and is useful for, for example, the prophylaxis or treatment of hyperuricemia, gout, etc.
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Inventors:
SUZUKI TOSHIHIDE
FUKIZAWA SHINYA
BEPPU YOSHINORI
WATANABE HIROSHI
FUKIZAWA SHINYA
BEPPU YOSHINORI
WATANABE HIROSHI
Application Number:
PCT/JP2014/066424
Publication Date:
December 23, 2015
Filing Date:
June 20, 2014
Export Citation:
Assignee:
SUNTORY HOLDINGS LTD (JP)
International Classes:
A61K38/00; A61P19/06; A61P43/00
Domestic Patent References:
| WO2009093141A2 | 2009-07-30 |
Foreign References:
| JP2013053115A | 2013-03-21 | |||
| JP2006111541A | 2006-04-27 |
Other References:
ALICE B. NONGONIERMA ET AL.: "Tryptophan- containing milk protein-derived dipeptides inhibit xanthine oxidase", PEPTIDES, vol. 37, no. 2, 2012, pages 263 - 72, XP055244800, ISSN: 0196-9781
Attorney, Agent or Firm:
HOSODA, YOSHINORI (JP)
Yoshinori Hosoda (JP)
Yoshinori Hosoda (JP)
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