Title:
USAGE OF POLY-3-HYDROXYALKANOATES IN PREPARATION OF β-LACTAM COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2007/098651
Kind Code:
A1
Abstract:
The present application has disclosed usage of poly-3-hydroxyalkanoates (P(3HB)) in preparation of β-lactam compounds. The present application has disclosed preparation method of β-lactam compounds of formula (I) by using P(3HB), in which definitions of the substitutents of formula (I) are the same as description. It is convenient to obtain compounds of formula (I) by utilizing the present method as it has shorter steps and higher yield, as well as avoids using agents which pollute environment or are expensive agents. So it is cost-effective and decreases pollution.
Inventors:
LU WEICHUAN (CN)
ZHANG QIAN (CN)
CHEN XIN (CN)
ZHANG QIAN (CN)
CHEN XIN (CN)
Application Number:
PCT/CN2006/002707
Publication Date:
September 07, 2007
Filing Date:
October 16, 2006
Export Citation:
Assignee:
TIANJIN GREEN BIOSCIENCES CO L (CN)
LU WEICHUAN (CN)
ZHANG QIAN (CN)
CHEN XIN (CN)
LU WEICHUAN (CN)
ZHANG QIAN (CN)
CHEN XIN (CN)
International Classes:
C07D205/08
Foreign References:
| CN85105097A | 1987-01-14 | |||
| CN85105098A | 1986-07-09 | |||
| US4861877A | 1989-08-29 | |||
| US4861877A | 1989-08-29 | |||
| CN85105097A | 1987-01-14 |
Other References:
BERKS A.H.: "Preparations of two pivotal intermediates for the synthesis of 1-b-methyl carbapenem antibiotics", TETRAHEDRON, vol. 52, no. 2, 1996, pages 331 - 375, XP026541797
HAYASHI T. ET AL.: "2-(Alkythio)penem-3-carboxylic acids. V. Synthesis and antibacterial activities of "1-thiathienamycin" and related compounds", CHEM. PHARM. BULL., vol. 29, no. 11, 1981, pages 3158 - 3172, XP008126291
SEEBACH D. ET AL.: "Depolymerization of poly[(R)-3-hydroxy-butanoate] (PHB)", HELV. CHIM. ACTA, vol. 65, no. 2, 1982, pages 495 - 503, XP008126286
See also references of EP 1990334A4
ANDREW H. BERKS, TETRAHYDRON, vol. 52, 1996, pages 331
YOSHIDA, A.; HAYASHI, T.; TAKEDA, N.; OIDA, S.; OHKI, E., CHEM. PHARM. BULL., vol. 29, 1981, pages 2899 - 2909
SHIOZAKI, M.; ISHIDA, N.; MARUYAMA, H.; HIRAOKA, T., TETRAHEDRON, vol. 39, 1983, pages 2399 - 2407
D1 BERKS A. H.: "Preparations of two pivotal intermediates for the synthesis of 1-b-methyl carbapenem antibiotics", TETRAHEDRON, vol. 52, no. 2, 1996, pages 331 - 375
HAYASHI T. ET AL.: "2-(Alkythio)penem-3-carboxylic acids. V. Synthesis and antibacterial activities of "1-thiathienamycin" and related compounds", CHEM. PHARM. BULL., vol. 29, no. 11, 1981, pages 3158 - 3172, XP008126291
SEEBACH D. ET AL.: "Depolymerization of poly[(R)-3-hydroxy-butanoate] (PHB)", HELV. CHIM. ACTA, vol. 65, no. 2, 1982, pages 495 - 503, XP008126286
See also references of EP 1990334A4
ANDREW H. BERKS, TETRAHYDRON, vol. 52, 1996, pages 331
YOSHIDA, A.; HAYASHI, T.; TAKEDA, N.; OIDA, S.; OHKI, E., CHEM. PHARM. BULL., vol. 29, 1981, pages 2899 - 2909
SHIOZAKI, M.; ISHIDA, N.; MARUYAMA, H.; HIRAOKA, T., TETRAHEDRON, vol. 39, 1983, pages 2399 - 2407
D1 BERKS A. H.: "Preparations of two pivotal intermediates for the synthesis of 1-b-methyl carbapenem antibiotics", TETRAHEDRON, vol. 52, no. 2, 1996, pages 331 - 375
Attorney, Agent or Firm:
INTELLECPRO CHINA LIMITED (Patent Division 11/F, Tower C, Five Buildings, 9 Chegongzhuang Daji, Xicheng District Beijing 4, CN)
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