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Title:
USE OF 2,4-DIHYDROXYBENZOIC ACID IN DRUG FOR TREATING IRON OVERLOAD DISEASES
Document Type and Number:
WIPO Patent Application WO/2023/109747
Kind Code:
A1
Abstract:
Disclosed is a use of 2,4-dihydroxybenzoic acid or a salt compound thereof in the preparation of a drug for treating iron overload diseases. Iron overload comprises exogenous iron overload and endogenous iron overload. Exogenous iron overload refers to iron overload caused by long-term dependency on blood transfusion. Related diseases caused by exogenous iron overload are selected from thalassemia, myelodysplastic syndrome, myelodysplastic anemia, or hemochromatosis. Related diseases caused by endogenous iron overload are selected from diabetes, hypertension, hyperlipidemia, hyperuricemia, coronary heart disease, stroke, vascular sclerosis, cirrhosis, pulmonary fibrosis, rheumatic arthritis, osteoporosis, Alzheimer's disease, tumor or aging.

Inventors:
ZHANG JIANGUO (CN)
LI CHENG (CN)
REN WUXIAN (CN)
HAN YINGBING (CN)
YA BANGQIN (CN)
Application Number:
PCT/CN2022/138376
Publication Date:
June 22, 2023
Filing Date:
December 12, 2022
Export Citation:
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Assignee:
HAOLA HAOLE SHANXI TECH CO LTD (CN)
ZHANG JIANGUO (CN)
LI CHENG (CN)
International Classes:
A61P1/16; A61K31/192; A61P3/06; A61P3/10; A61P7/00; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P19/02; A61P19/06; A61P19/10; A61P25/28; A61P35/00
Domestic Patent References:
WO2021057680A12021-04-01
WO1998020905A21998-05-22
Foreign References:
CN114191425A2022-03-18
US20030220230A12003-11-27
US20130056211A12013-03-07
Attorney, Agent or Firm:
PATENTSINO IP FIRM (CN)
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