Title:
USE OF ACTIVE COMPOUND IN PREVENTION OR TREATMENT OF OVARIAN DYSFUNCTION DISEASES
Document Type and Number:
WIPO Patent Application WO/2023/206903
Kind Code:
A1
Abstract:
The present disclosure relates to use of an active compound in the prevention or treatment of ovarian dysfunction diseases. Specifically, the present disclosure relates to use of a compound represented by formula (I) or a pharmaceutically acceptable salt thereof in the treatment or prevention of ovarian dysfunction diseases, wherein R1 and R2 are each independently selected from H, C1-C6 alkyl, C1-C6 alkenyl, and C1-C6 alkynyl. The present disclosure further relates to use of the compound represented by formula (I) or the pharmaceutically acceptable salt thereof in combination with hyodeoxycholic acid or a pharmaceutically acceptable salt thereof in the treatment or prevention of ovarian dysfunction diseases. The present disclosure further relates to a composition comprising represented by formula I or the pharmaceutically acceptable salt thereof and/or hyodeoxycholic acid or the pharmaceutically acceptable salt thereof.
Inventors:
LU CUILING (CN)
JIANG TAO (CN)
YI YANXIAO (CN)
JIANG TAO (CN)
YI YANXIAO (CN)
Application Number:
PCT/CN2022/116863
Publication Date:
November 02, 2023
Filing Date:
September 02, 2022
Export Citation:
Assignee:
INST BIOPHYSICS CAS (CN)
International Classes:
A61K31/575; A61K31/225; A61P15/08
Domestic Patent References:
| WO2010069139A1 | 2010-06-24 |
Foreign References:
| US20170056356A1 | 2017-03-02 | |||
| US20210283089A1 | 2021-09-16 | |||
| CN114917215A | 2022-08-19 |
Other References:
ZHEN XU ET AL: "Protective Effects of Dimethyl Fumarate on Renal Ischemia-reperfusion Injury in Mice and Its Mechanisms", XIANDAI MINIAO WAIKE ZAZHI - JOURNAL OF MODERN UROLOGY, XI'AN JIAOTONG DAXUE YIXUEYUAN, CN, vol. 22, no. 8, 30 August 2017 (2017-08-30), CN , pages 621 - 624, XP009521560, ISSN: 1009-8291
MA, ZHIQIANG; ZUO, YAN; ZHANG, YI: "Relationship between Dimethyl Fumarate and Oxidative Stress in Renal Calci-Um Oxalate Stone Model Rats", JOURNAL OF NORTH SICHUAN MEDICAL COLLEGE, CN, vol. 35, no. 1, 15 February 2020 (2020-02-15), CN, pages 10 - 13, XP009550149, ISSN: 1005-3697, DOI: 10.3969/j.issn.1005-3697.2020.01.03
MA, ZHIQIANG; ZUO, YAN; ZHANG, YI: "Relationship between Dimethyl Fumarate and Oxidative Stress in Renal Calci-Um Oxalate Stone Model Rats", JOURNAL OF NORTH SICHUAN MEDICAL COLLEGE, CN, vol. 35, no. 1, 15 February 2020 (2020-02-15), CN, pages 10 - 13, XP009550149, ISSN: 1005-3697, DOI: 10.3969/j.issn.1005-3697.2020.01.03
Attorney, Agent or Firm:
IPSUNNY (CN)
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