USE OF ADENO-ASSOCIATED VIRUSES FOR DECREASING THE RADIOTHERAPY-INDUCED OR CHEMOTHERAPY-INDUCED RESISTANCE IN CANCER PATIENTS

Title:

USE OF ADENO-ASSOCIATED VIRUSES FOR DECREASING THE RADIOTHERAPY-INDUCED OR CHEMOTHERAPY-INDUCED RESISTANCE IN CANCER PATIENTS

Document Type and Number:

WIPO Patent Application WO1999064024

Kind Code:

A3

Abstract:

The invention relates to the use of adeno-associated viruses for decreasing the radiotherapy-induced or chemotherapy-induced resistance in patients who suffer from a cancer which is to be treated by radiotherapy or chemotherapy.

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Inventors:

VON KNEBEL-DOEBERITZ MAGNUS (DE)
KLEIN-BAUERNSCHMITT PETRA (DE)
ZUR HAUSEN HARALD (DE)
SCHLEHOFER JOERG (DE)

Application Number:

PCT/DE1999/001711

Publication Date:

March 09, 2000

Filing Date:

June 08, 1999

Export Citation:

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Assignee:

DEUTSCHES KREBSFORSCH (DE)
VON KNEBEL DOEBERITZ MAGNUS (DE)
KLEIN BAUERNSCHMITT PETRA (DE)
ZUR HAUSEN HARALD (DE)
SCHLEHOFER JOERG (DE)

International Classes:

A61K35/76; A61P35/00; (IPC1-7): A61K35/76

Domestic Patent References:

WO1996018737A2

1996-06-20

Other References:

KLEIN-BAUERNSCHMITT P ET AL: "Improved efficacy of chemotherapy by parvovirus-mediated sensitisation of human tumour cells.", EUROPEAN JOURNAL OF CANCER, (1996 SEP) 32A (10) 1774-80., XP000867207
HILLGENBERG M ET AL: "Enhanced sensitivity of small cell lung cancer cell lines to cisplatin and etoposide after infection with adeno-associated virus type 2.", EUROPEAN JOURNAL OF CANCER, (1999 JAN) 35 (1) 106-10., XP000867208

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