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Title:
USE OF ADENO-ASSOCIATED VIRUSES FOR DECREASING THE RADIOTHERAPY-INDUCED OR CHEMOTHERAPY-INDUCED RESISTANCE IN CANCER PATIENTS
Document Type and Number:
WIPO Patent Application WO1999064024
Kind Code:
A3
Abstract:
The invention relates to the use of adeno-associated viruses for decreasing the radiotherapy-induced or chemotherapy-induced resistance in patients who suffer from a cancer which is to be treated by radiotherapy or chemotherapy.

Inventors:
VON KNEBEL-DOEBERITZ MAGNUS (DE)
KLEIN-BAUERNSCHMITT PETRA (DE)
ZUR HAUSEN HARALD (DE)
SCHLEHOFER JOERG (DE)
Application Number:
PCT/DE1999/001711
Publication Date:
March 09, 2000
Filing Date:
June 08, 1999
Export Citation:
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Assignee:
DEUTSCHES KREBSFORSCH (DE)
VON KNEBEL DOEBERITZ MAGNUS (DE)
KLEIN BAUERNSCHMITT PETRA (DE)
ZUR HAUSEN HARALD (DE)
SCHLEHOFER JOERG (DE)
International Classes:
A61K35/76; A61P35/00; (IPC1-7): A61K35/76
Domestic Patent References:
WO1996018737A21996-06-20
Other References:
KLEIN-BAUERNSCHMITT P ET AL: "Improved efficacy of chemotherapy by parvovirus-mediated sensitisation of human tumour cells.", EUROPEAN JOURNAL OF CANCER, (1996 SEP) 32A (10) 1774-80., XP000867207
HILLGENBERG M ET AL: "Enhanced sensitivity of small cell lung cancer cell lines to cisplatin and etoposide after infection with adeno-associated virus type 2.", EUROPEAN JOURNAL OF CANCER, (1999 JAN) 35 (1) 106-10., XP000867208
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