Title:
USE OF ALLICIN AS PRESERVATIVE, AS DISINFECTANT, AS ANTIMICROBIAL OR AS BIOCIDAL AGENT
Document Type and Number:
WIPO Patent Application WO2004084645
Kind Code:
A3
Abstract:
The present invention provides the use of allicin in (i) the treatment of leishmaniasis; (ii) as a disinfectant or biocidal treatment of aquatic species; (iii) as an antimicrobial agent for animal feed; (iv) as a preservative agent in foodstuffs; (v) as a water disinfectant or biocide; (vi) as an antiparasitic treatment or antibacterial treatment for bees (apis); or (vii) in the preparation of a medicament for the treatment of Glycopeptide Intermediate Resistant Stapohylococcus Aureus.
Inventors:
BENNETT NORMAN JOHN (GB)
JOSLING PETER DAVID (GB)
JOSLING PETER DAVID (GB)
Application Number:
PCT/GB2004/001408
Publication Date:
March 24, 2005
Filing Date:
March 29, 2004
Export Citation:
Assignee:
STONE ISLAND HOLDINGS LTD (GB)
BENNETT NORMAN JOHN (GB)
JOSLING PETER DAVID (GB)
BENNETT NORMAN JOHN (GB)
JOSLING PETER DAVID (GB)
International Classes:
A01N41/02; A23K1/16; A23K1/18; A23L3/3535; A61K31/255; A61L2/00; A61L2/16; A61P31/04; A61P31/10; A61P33/00; A61P33/02; C02F1/50; (IPC1-7): A23K1/17; A23L3/3535; A61P31/10; C02F1/50; A61K31/255; A01N59/02; A61P33/00; A61P31/04; A61P33/02
Domestic Patent References:
| WO1999027940A1 | 1999-06-10 | |||
| WO1997039115A1 | 1997-10-23 | |||
| WO1990014012A1 | 1990-11-29 | |||
| WO2003024437A1 | 2003-03-27 |
Foreign References:
| US5906825A | 1999-05-25 | |||
| US5705152A | 1998-01-06 |
Other References:
ANKRI SERGE ET AL: "Antimicrobial properties of allicin from garlic", MICROBES AND INFECTION, vol. 1, no. 2, February 1999 (1999-02-01), pages 125 - 129, XP002289130, ISSN: 1286-4579
MCCLURE C ET AL: "Effect of medicinal plant extracts on the growth of Leishmania sp. and mammalian cell lines", ABSTRACTS OF THE GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY, vol. 94, no. 0, 1994, & 94TH GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY; LAS VEGAS, NEVADA, USA; MAY 23-27, 1994, pages 18, XP009033991, ISSN: 1060-2011
MCCLURE, CHRISTOPHER D. ET AL: "Antileishmanial properties of Allium sativum extracts and derivatives", ACTA HORTICULTURAE , 426(INTERNATIONAL SYMPOSIUM ON MEDICINAL AND AROMATIC PLANTS, 1995), 183-191 CODEN: AHORA2; ISSN: 0567-7572, 1996, XP009034093
GHAZANFARI T ET AL: "Garlic induces a shift in cytokine pattern in Leishmania major-infected BALB/c mice", SCANDINAVIAN JOURNAL OF IMMUNOLOGY, vol. 52, no. 5, November 2000 (2000-11-01), pages 491 - 495, XP002289131, ISSN: 0300-9475
LEDEZMA ELIADES ET AL: "Antiproliferative and leishmanicidal effect of ajoene on various Leishmania species: Ultrastructural study", PARASITOLOGY RESEARCH, vol. 88, no. 8, August 2002 (2002-08-01), pages 748 - 753, XP002289132, ISSN: 0932-0113
AHMADI-RENANI K ET AL: "Effect of garlic extract on cutaneous leishmaniasis and the role of nitric oxide", IRANIAN JOURNAL OF MEDICAL SCIENCES 2002 IRAN, vol. 27, no. 3, 2002, pages 97 - 100, XP009034067, ISSN: 0253-0716
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 11 September 1997 (1997-09-11), TIAN, XUEJUN: "Chemical inhibition of Ascophaera apis Olive & Spiltoir", XP002299152, retrieved from STN Database accession no. 1997:577673
SANDHU D K ET AL: "SENSITIVITY OF YEASTS ISOLATED FROM CASES OF VAGINITIS TO AQUEOUS EXTRACTS OF GARLIC", MYKOSEN, vol. 23, no. 12, 1980, pages 691 - 698, XP009037478, ISSN: 0027-5557
FARBMAN K S: "ANTIBACTERIAL ACTIVITY OF GARLIC AND ONIONS: A HISTORICAL PERSPECTIVE", PEDIATRIC INFECTIOUS DISEASE JOURNAL, WILLIAMS & WILKINS, BALTIMORE, MD, US, vol. 12, no. 7, 1 July 1993 (1993-07-01), pages 613 - 614, XP002051069, ISSN: 0891-3668
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 2001, CUTLER R R ET AL: "Activity of a novel, stable, Allicin extract, in liquid and cream formulations, against methicillin resistant Staphylococcus aureus (MRSA) including mupirocin resistant MRSAs", XP002299153, Database accession no. PREV200200555330
MCCLURE C ET AL: "Effect of medicinal plant extracts on the growth of Leishmania sp. and mammalian cell lines", ABSTRACTS OF THE GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY, vol. 94, no. 0, 1994, & 94TH GENERAL MEETING OF THE AMERICAN SOCIETY FOR MICROBIOLOGY; LAS VEGAS, NEVADA, USA; MAY 23-27, 1994, pages 18, XP009033991, ISSN: 1060-2011
MCCLURE, CHRISTOPHER D. ET AL: "Antileishmanial properties of Allium sativum extracts and derivatives", ACTA HORTICULTURAE , 426(INTERNATIONAL SYMPOSIUM ON MEDICINAL AND AROMATIC PLANTS, 1995), 183-191 CODEN: AHORA2; ISSN: 0567-7572, 1996, XP009034093
GHAZANFARI T ET AL: "Garlic induces a shift in cytokine pattern in Leishmania major-infected BALB/c mice", SCANDINAVIAN JOURNAL OF IMMUNOLOGY, vol. 52, no. 5, November 2000 (2000-11-01), pages 491 - 495, XP002289131, ISSN: 0300-9475
LEDEZMA ELIADES ET AL: "Antiproliferative and leishmanicidal effect of ajoene on various Leishmania species: Ultrastructural study", PARASITOLOGY RESEARCH, vol. 88, no. 8, August 2002 (2002-08-01), pages 748 - 753, XP002289132, ISSN: 0932-0113
AHMADI-RENANI K ET AL: "Effect of garlic extract on cutaneous leishmaniasis and the role of nitric oxide", IRANIAN JOURNAL OF MEDICAL SCIENCES 2002 IRAN, vol. 27, no. 3, 2002, pages 97 - 100, XP009034067, ISSN: 0253-0716
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 11 September 1997 (1997-09-11), TIAN, XUEJUN: "Chemical inhibition of Ascophaera apis Olive & Spiltoir", XP002299152, retrieved from STN Database accession no. 1997:577673
SANDHU D K ET AL: "SENSITIVITY OF YEASTS ISOLATED FROM CASES OF VAGINITIS TO AQUEOUS EXTRACTS OF GARLIC", MYKOSEN, vol. 23, no. 12, 1980, pages 691 - 698, XP009037478, ISSN: 0027-5557
FARBMAN K S: "ANTIBACTERIAL ACTIVITY OF GARLIC AND ONIONS: A HISTORICAL PERSPECTIVE", PEDIATRIC INFECTIOUS DISEASE JOURNAL, WILLIAMS & WILKINS, BALTIMORE, MD, US, vol. 12, no. 7, 1 July 1993 (1993-07-01), pages 613 - 614, XP002051069, ISSN: 0891-3668
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 2001, CUTLER R R ET AL: "Activity of a novel, stable, Allicin extract, in liquid and cream formulations, against methicillin resistant Staphylococcus aureus (MRSA) including mupirocin resistant MRSAs", XP002299153, Database accession no. PREV200200555330
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