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Patent Searching and Data


Title:
USE OF AMINOMETHYLENECYCLOHEXANE-1,3-DIONE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2018/214814
Kind Code:
A1
Abstract:
A use of an aminomethylenecyclohexane-1,3-dione compound. In particular, the present invention relates to a use of a compound shown in the following formula (I) or a pharmaceutically acceptable salt thereof alone or in combination with other drug in preparing a drug for regulating or treating a disease related to autophagy, especially targeting a mammalian ATG8 homologue.

Inventors:
LUO CHENG (CN)
YUE LIYAN (CN)
WAN WEI (CN)
ZHANG YUANYUAN (CN)
JIANG HUALIANG (CN)
CHEN KAIXIAN (CN)
Application Number:
PCT/CN2018/087452
Publication Date:
November 29, 2018
Filing Date:
May 18, 2018
Export Citation:
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Assignee:
SUZHOU AUTOPHARM BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
C07C13/18; A61K31/00; A61P35/00; C07C11/02; C07C50/00
Domestic Patent References:
WO2011033389A22011-03-24
Foreign References:
CN103977002A2014-08-13
US20090163545A12009-06-25
US20150166492A12015-06-18
Other References:
CANELA, M. ET AL.: "Targeting the Colchicine Site in Tubulin through Cyclohexanedione Derivatives", RSC ADV., vol. 6, 9 February 2016 (2016-02-09), pages 19492 - 19506, XP055550396
Attorney, Agent or Firm:
KINGSOUND & PARTNERS (CN)
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