Title:
USE OF AMINOMETHYLENECYCLOHEXANE-1,3-DIONE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2018/214814
Kind Code:
A1
Abstract:
A use of an aminomethylenecyclohexane-1,3-dione compound. In particular, the present invention relates to a use of a compound shown in the following formula (I) or a pharmaceutically acceptable salt thereof alone or in combination with other drug in preparing a drug for regulating or treating a disease related to autophagy, especially targeting a mammalian ATG8 homologue.
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Inventors:
LUO CHENG (CN)
YUE LIYAN (CN)
WAN WEI (CN)
ZHANG YUANYUAN (CN)
JIANG HUALIANG (CN)
CHEN KAIXIAN (CN)
YUE LIYAN (CN)
WAN WEI (CN)
ZHANG YUANYUAN (CN)
JIANG HUALIANG (CN)
CHEN KAIXIAN (CN)
Application Number:
PCT/CN2018/087452
Publication Date:
November 29, 2018
Filing Date:
May 18, 2018
Export Citation:
Assignee:
SUZHOU AUTOPHARM BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
C07C13/18; A61K31/00; A61P35/00; C07C11/02; C07C50/00
Domestic Patent References:
WO2011033389A2 | 2011-03-24 |
Foreign References:
CN103977002A | 2014-08-13 | |||
US20090163545A1 | 2009-06-25 | |||
US20150166492A1 | 2015-06-18 |
Other References:
CANELA, M. ET AL.: "Targeting the Colchicine Site in Tubulin through Cyclohexanedione Derivatives", RSC ADV., vol. 6, 9 February 2016 (2016-02-09), pages 19492 - 19506, XP055550396
Attorney, Agent or Firm:
KINGSOUND & PARTNERS (CN)
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