Title:
USE AS SELECTIVE AGONIST OF MALANOCORTIN-4 RECEPTOR
Document Type and Number:
WIPO Patent Application WO/2022/139406
Kind Code:
A1
Abstract:
The present invention relates to use of a compound of chemical formula 1 or a pharmaceutically acceptable salt thereof as a selective agonist of the melanocortin-4-receptor (MC4R).
Inventors:
PARK HEE DONG (KR)
YEO SU JIN (KR)
PARK HYUN SEO (KR)
PARK JIN SOOK (KR)
AHN HYE WON (KR)
YEO SU JIN (KR)
PARK HYUN SEO (KR)
PARK JIN SOOK (KR)
AHN HYE WON (KR)
Application Number:
PCT/KR2021/019500
Publication Date:
June 30, 2022
Filing Date:
December 21, 2021
Export Citation:
Assignee:
LG CHEMICAL LTD (KR)
International Classes:
A61K31/5377; A61K9/00; A61P3/04; A61P3/10; A61P15/10; A61P29/00
Domestic Patent References:
| WO2000074679A1 | 2000-12-14 | |||
| WO2021091283A1 | 2021-05-14 |
Foreign References:
| KR20100053458A | 2010-05-20 | |||
| US20070129346A1 | 2007-06-07 | |||
| US20040058936A1 | 2004-03-25 |
Other References:
SPENCER J. D., SCHALLREUTER K. U.: "Regulation of Pigmentation in Human Epidermal Melanocytes by Functional High-Affinity β-Melanocyte-Stimulating Hormone/Melanocortin-4 Receptor Signaling", ENDOCRINOLOGY, vol. 150, no. 3, 1 March 2009 (2009-03-01), US , pages 1250 - 1258, XP055946169, ISSN: 0013-7227, DOI: 10.1210/en.2008-1212
MACNEIL DJ ET AL., EUR J PHARMACOL, vol. 450, 2002, pages 93
LU DWILLARD D ET AL., NATURE, vol. 371, no. 6500, 1994, pages 799
HUSZAR D ET AL., CELL, vol. 88, no. 1, 1997, pages 131
HINNEY A ET AL., J CLIN ENDOCRINOL METAB, vol. 84, no. 4, 1990, pages 1483
WIKBERG ET AL., EUR. J. PHARMACOL, vol. 375, 1999, pages 295 - 310
WIKBERG ET AL., PHARM RES, vol. 42, no. 5, 2000, pages 393 - 420
DOUGLAS ET AL., EUR J PHARM, vol. 450, 2002, pages 93 - 109
O'RAHILLY ET AL., NATURE MED, vol. 10, 2004, pages 351 - 352
CLEMENT ET AL., NATURE MEDICINE, 2018
MACNEIL DJ ET AL., EUR J PHARMACOL, vol. 450, 2002, pages 93
LU DWILLARD D ET AL., NATURE, vol. 371, no. 6500, 1994, pages 799
HUSZAR D ET AL., CELL, vol. 88, no. 1, 1997, pages 131
HINNEY A ET AL., J CLIN ENDOCRINOL METAB, vol. 84, no. 4, 1990, pages 1483
WIKBERG ET AL., EUR. J. PHARMACOL, vol. 375, 1999, pages 295 - 310
WIKBERG ET AL., PHARM RES, vol. 42, no. 5, 2000, pages 393 - 420
DOUGLAS ET AL., EUR J PHARM, vol. 450, 2002, pages 93 - 109
O'RAHILLY ET AL., NATURE MED, vol. 10, 2004, pages 351 - 352
CLEMENT ET AL., NATURE MEDICINE, 2018
Attorney, Agent or Firm:
HANSUNG INTELLECTUAL PROPERTY (KR)
Download PDF: