Title:
USE OF β-AS4S4 IN PREPARATION OF MEDICAMENT FOR TREATMENT OF HEMATOLOGICAL MALIGNANCY
Document Type and Number:
WIPO Patent Application WO/2018/153227
Kind Code:
A1
Abstract:
A use of β-As4S4 in the preparation of a medicament for the treatment of hematological malignancies. The hematologic malignancies are selected from leukemia, lymphoma, multiple myeloma, myelodysplastic syndrome, refractory anemia with excess naive cells, and refractory anemia in transformation to leukemia. Compared with natural realgar, the β-As4S4 has a better dissolution in pure water and human gastrointestinal fluid and has a better effect in inducing apoptosis in hematological malignant cells.
Inventors:
ZHANG ZHIJIE (CN)
HUANG XIANGBIN (CN)
HUANG XIANGBIN (CN)
Application Number:
PCT/CN2018/074666
Publication Date:
August 30, 2018
Filing Date:
January 31, 2018
Export Citation:
Assignee:
SICHUAN SINCO PHARMACEUTICAL CO LTD (CN)
International Classes:
A61P35/00; A61K33/36
Foreign References:
| CN101884648A | 2010-11-17 |
Other References:
TIAN, JIN'GAI ET AL.: "The Powder X-Ray Diffraction Analysis of Mineral Drug Realgar with Its Associated Minerals", CHINESE JOURNAL OF PHARMACEUTICAL ANALYSIS, vol. 18, no. 02, 31 March 1998 (1998-03-31), pages 88
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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