Title:
USE OF BACTEROIDES FRAGILIS IN PREVENTION AND TREATMENT OF CANCER-RELATED DIARRHEA
Document Type and Number:
WIPO Patent Application WO/2023/061154
Kind Code:
A1
Abstract:
Provided in the present invention is the use of Bacteroides fragilis in the prevention and treatment of cancer treatment-induced diarrhea. Specifically, provided is the use of Bacteroides fragilis in cancer treatment-induced diarrhea. In addition, further provided in the present invention is the use of Bacteroides fragilis in the preparation of a composition for preventing and/or treating side effects of chemotherapy or targeted drugs, such as food intake change, body weight change, diarrhea, inflammatory factor increase, intestinal mucosa injury, mucosa congestion, inflammatory cell infiltration and/or gland damage.
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Inventors:
LIU YANGYANG (CN)
ZHENG LIJUN (CN)
CHANG XIUJUAN (CN)
LIANG DEBAO (CN)
WANG YE (CN)
ZHI FACHAO (CN)
ZHENG LIJUN (CN)
CHANG XIUJUAN (CN)
LIANG DEBAO (CN)
WANG YE (CN)
ZHI FACHAO (CN)
Application Number:
PCT/CN2022/119521
Publication Date:
April 20, 2023
Filing Date:
September 19, 2022
Export Citation:
Assignee:
GUANGZHOU ZHIYI BIOTECHNOLOGY CO LTD (CN)
International Classes:
A61K35/74; A61P1/12; C12N1/20; C12R1/01
Domestic Patent References:
| WO2018014833A1 | 2018-01-25 | |||
| WO2017020784A1 | 2017-02-09 | |||
| WO2019047439A1 | 2019-03-14 |
Foreign References:
| CN114558036A | 2022-05-31 | |||
| CN107625791A | 2018-01-26 | |||
| CN106399141A | 2017-02-15 | |||
| CN109481475A | 2019-03-19 | |||
| CN105434476A | 2016-03-30 | |||
| CN103082294A | 2013-05-08 | |||
| CN109481472A | 2019-03-19 | |||
| CN109481473A | 2019-03-19 |
Other References:
TUTENG059: "Bacteroides fragilis BF839 alleviates diarrhea and abdominal pain in patients with cancer", ZHIHU, XP009546650, Retrieved from the Internet
FAN, HONGYING: "Efficacy and Mechanism of Bacteroides Fragilis on the Prevention and Treatment of Cronobacter Sakazakii-induced Necrotizing Enterocolitis", MEDICAL AND HEALTH SCIENCES, CHINA DOCTORAL DISSERTATIONS FULL-TEXT DATABASE, no. 2, 1 September 2019 (2019-09-01), CN, pages 1 - 106, XP009545064, DOI: 10.27003/d.cnki.gojyu
SONG XIAOLIAN, BAI CHONG : "Treatment-Induced Digestive System Toxicity in Patients with Cancer", PHARMACEUTICAL CARE AND RESEARCH (YAOXUE FUWU YU YANJIU), DI-ER JUNYI DAXUE CHANGHAI YIYUAN, CN, vol. 5, no. 4, 31 December 2005 (2005-12-31), CN , pages 385 - 387, XP093058410, ISSN: 1671-2838
FAN, HONGYING: "Efficacy and Mechanism of Bacteroides Fragilis on the Prevention and Treatment of Cronobacter Sakazakii-induced Necrotizing Enterocolitis", MEDICAL AND HEALTH SCIENCES, CHINA DOCTORAL DISSERTATIONS FULL-TEXT DATABASE, no. 2, 1 September 2019 (2019-09-01), CN, pages 1 - 106, XP009545064, DOI: 10.27003/d.cnki.gojyu
SONG XIAOLIAN, BAI CHONG : "Treatment-Induced Digestive System Toxicity in Patients with Cancer", PHARMACEUTICAL CARE AND RESEARCH (YAOXUE FUWU YU YANJIU), DI-ER JUNYI DAXUE CHANGHAI YIYUAN, CN, vol. 5, no. 4, 31 December 2005 (2005-12-31), CN , pages 385 - 387, XP093058410, ISSN: 1671-2838
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
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