Title:
USE OF BAIJIU IN PREPARING DRUG FOR IMPROVING INTESTINAL BARRIER FUNCTION AND INTESTINAL FLORA
Document Type and Number:
WIPO Patent Application WO/2023/240935
Kind Code:
A1
Abstract:
The present invention provides use of Baijiu in preparing a drug for improving an intestinal barrier function and intestinal flora, belonging to the technical field of medicine and health care. According to the present invention, by evaluating the effects of 52% vol Shede wine on the intestinal barrier function and intestinal flora of rats, it is found that drinking a proper amount of 52% vol Shede wine has a certain degree of protection effect on an intestinal barrier, and can relieve inflammation and regulate the intestinal flora, providing references for the benefits of drinking a proper amount of 52% vol Shede wine on a human body.
Inventors:
PU JIZHOU (CN)
RAO JIAQUAN (CN)
YUAN JIELI (CN)
LI MING (CN)
WANG XIAOPING (CN)
ZOU YONGFANG (CN)
WEN JING (CN)
RAO JIAQUAN (CN)
YUAN JIELI (CN)
LI MING (CN)
WANG XIAOPING (CN)
ZOU YONGFANG (CN)
WEN JING (CN)
Application Number:
PCT/CN2022/135288
Publication Date:
December 21, 2023
Filing Date:
November 30, 2022
Export Citation:
Assignee:
SHEDE SPIRITS CO LTD (CN)
UNIV DALIAN MEDICAL (CN)
UNIV DALIAN MEDICAL (CN)
International Classes:
A61K31/045; A61P1/00
Foreign References:
| CN114917208A | 2022-08-19 |
Other References:
FANG CHENG, ZHOU QINGWU, LIU QINGYANG, JIA WEI, XU YAN: "Crosstalk between gut microbiota and host lipid metabolism in a mouse model of alcoholic liver injury by chronic baijiu or ethanol feeding", FOOD & FUNCTION, R S C PUBLICATIONS, GB, vol. 13, no. 2, 24 January 2022 (2022-01-24), GB , pages 596 - 608, XP093118370, ISSN: 2042-6496, DOI: 10.1039/D1FO02892H
FANG CHENG, DU HAI, ZHENG XIAOJIAO, ZHAO AIHUA, JIA WEI, XU YAN: "Solid‐state fermented Chinese alcoholic beverage (baijiu) and ethanol resulted in distinct metabolic and microbiome responses", THE FASEB JOURNAL, FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY, US, vol. 33, no. 6, 1 June 2019 (2019-06-01), US, pages 7274 - 7288, XP093118373, ISSN: 0892-6638, DOI: 10.1096/fj.201802306R
JI MEI, FANG CHENG, JIA WEI, DU HAI, XU YAN: "Regulatory effect of volatile compounds in fermented alcoholic beverages on gut microbiota and serum metabolism in a mouse model", FOOD & FUNCTION, R S C PUBLICATIONS, GB, vol. 12, no. 12, 21 June 2021 (2021-06-21), GB , pages 5576 - 5590, XP093118375, ISSN: 2042-6496, DOI: 10.1039/D0FO03028G
WANG SHIXIN,, KAI LANG, YANG JINGY , JI XINGMING, QIAN HANQI , XU YAN, DU HAI.: "Ｒesearch progress on health effects of short-chain fatty acids and its ethyl esters in strong aroma-type Baijiu", FOOD AND FERMENTATION INDUSTRIES., vol. 46, no. 16, 1 April 2020 (2020-04-01), pages 257 - 263, XP093118384, DOI: 10.13995/j.cnki.11-1802/ts.023723
ZOU YONGFANG, YU DONG, WEN JING, YUAN JIELI, YUE PEI, JIANG ANHUA: "Effects Of Traditional Solid Liquor On Intestinal Microecology In Rats", LIQUOR MAKING., vol. 47, no. 2, 1 March 2020 (2020-03-01), pages 51 - 55, XP093118394, DOI: 1002-8110(2020)02-0051-05
FANG CHENG, DU HAI, ZHENG XIAOJIAO, ZHAO AIHUA, JIA WEI, XU YAN: "Solid‐state fermented Chinese alcoholic beverage (baijiu) and ethanol resulted in distinct metabolic and microbiome responses", THE FASEB JOURNAL, FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY, US, vol. 33, no. 6, 1 June 2019 (2019-06-01), US, pages 7274 - 7288, XP093118373, ISSN: 0892-6638, DOI: 10.1096/fj.201802306R
JI MEI, FANG CHENG, JIA WEI, DU HAI, XU YAN: "Regulatory effect of volatile compounds in fermented alcoholic beverages on gut microbiota and serum metabolism in a mouse model", FOOD & FUNCTION, R S C PUBLICATIONS, GB, vol. 12, no. 12, 21 June 2021 (2021-06-21), GB , pages 5576 - 5590, XP093118375, ISSN: 2042-6496, DOI: 10.1039/D0FO03028G
WANG SHIXIN,, KAI LANG, YANG JINGY , JI XINGMING, QIAN HANQI , XU YAN, DU HAI.: "Ｒesearch progress on health effects of short-chain fatty acids and its ethyl esters in strong aroma-type Baijiu", FOOD AND FERMENTATION INDUSTRIES., vol. 46, no. 16, 1 April 2020 (2020-04-01), pages 257 - 263, XP093118384, DOI: 10.13995/j.cnki.11-1802/ts.023723
ZOU YONGFANG, YU DONG, WEN JING, YUAN JIELI, YUE PEI, JIANG ANHUA: "Effects Of Traditional Solid Liquor On Intestinal Microecology In Rats", LIQUOR MAKING., vol. 47, no. 2, 1 March 2020 (2020-03-01), pages 51 - 55, XP093118394, DOI: 1002-8110(2020)02-0051-05
Attorney, Agent or Firm:
BEIJING GAOWO LAW FIRM (CN)
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