Title:
USE OF BIGLYCAN IN THE ASSESSMENT OF HEART FAILURE
Document Type and Number:
WIPO Patent Application WO/2010/043393
Kind Code:
A8
Abstract:
The invention relates to a method for assessing heart failure in vitro comprising the steps of measuring in a sample the concentration of the marker biglycan, of optionally measuring in the sample the concentration of one or more other marker(s) of heart failure, and of assessing heart failure by comparing the concentration determined in for biglycan and the concentration(s) determined for the optionally one or more other marker to the concentration of this marker or these markers as established in a reference population. Also disclosed are the use of biglycan as a marker protein in the assessment of heart failure, a marker combination comprising biglycan and a kit for measuring biglycan.
Inventors:
WIENHUES-THELEN URSULA-HENRIKE (DE)
ARAB SARA (CA)
BLOCK DIRK (DE)
EMILI ANDREW (CA)
GRAMOLINI ANTHONY (CA)
HESS GEORG (DE)
HUEDIG HENDRIK (DE)
LIU PETER (CA)
MACLENNAN DAVID (CA)
ARAB SARA (CA)
BLOCK DIRK (DE)
EMILI ANDREW (CA)
GRAMOLINI ANTHONY (CA)
HESS GEORG (DE)
HUEDIG HENDRIK (DE)
LIU PETER (CA)
MACLENNAN DAVID (CA)
Application Number:
PCT/EP2009/007399
Publication Date:
February 24, 2011
Filing Date:
October 15, 2009
Export Citation:
Assignee:
ROCHE DIAGNOSTICS GMBH (DE)
HOFFMANN LA ROCHE (CH)
UNIV TORONTO (CA)
WIENHUES-THELEN URSULA-HENRIKE (DE)
ARAB SARA (CA)
BLOCK DIRK (DE)
EMILI ANDREW (CA)
GRAMOLINI ANTHONY (CA)
HESS GEORG (DE)
HUEDIG HENDRIK (DE)
LIU PETER (CA)
MACLENNAN DAVID (CA)
HOFFMANN LA ROCHE (CH)
UNIV TORONTO (CA)
WIENHUES-THELEN URSULA-HENRIKE (DE)
ARAB SARA (CA)
BLOCK DIRK (DE)
EMILI ANDREW (CA)
GRAMOLINI ANTHONY (CA)
HESS GEORG (DE)
HUEDIG HENDRIK (DE)
LIU PETER (CA)
MACLENNAN DAVID (CA)
International Classes:
G01N33/68
Attorney, Agent or Firm:
ROCHE DIAGNOSTICS GMBH (WernerPatent Department, Postfach 11 52 Penzberg, DE)
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