Title:
USE OF CHIAURANIB IN COMBINATION WITH IMMUNE CHECKPOINT INHIBITOR IN ANTITUMOR THERAPY
Document Type and Number:
WIPO Patent Application WO/2022/052874
Kind Code:
A1
Abstract:
The present invention relates to the field of medicines, and in particular relates to a use of chiauranib in combination with an immune checkpoint inhibitor in antitumor therapy. A use of a combination of chiauranib or a derivative thereof and the immune checkpoint inhibitor in the preparation of a medicine for treating a tumor, a pharmaceutical composition and a kit comprising the combination, and a method for treating a tumor by administering a therapeutically effective amount of the pharmaceutical composition or the kit to a tumor patient in need thereof. The combination has a synergistic effect and is suitable for treating a cancer.
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Inventors:
LU XIANPING (CN)
PAN DESI (CN)
ZHOU YOU (CN)
PAN DESI (CN)
ZHOU YOU (CN)
Application Number:
PCT/CN2021/116498
Publication Date:
March 17, 2022
Filing Date:
September 03, 2021
Export Citation:
Assignee:
SHENZHEN CHIPSCREEN BIOSCIENCES CO LTD (CN)
CHENGDU CHIPSCREEN PHARMACEUTICAL LTD (CN)
CHENGDU CHIPSCREEN PHARMACEUTICAL LTD (CN)
International Classes:
A61K39/395; A61K31/47; A61P35/00
Domestic Patent References:
| WO2019096194A1 | 2019-05-23 | |||
| WO2018223923A1 | 2018-12-13 | |||
| WO2020034916A1 | 2020-02-20 | |||
| WO2019201195A1 | 2019-10-24 | |||
| WO2018059429A1 | 2018-04-05 | |||
| WO2015088847A1 | 2015-06-18 | |||
| WO2016141218A1 | 2016-09-09 | |||
| WO2019096194A1 | 2019-05-23 |
Foreign References:
| CN109893654A | 2019-06-18 | |||
| CN112741905A | 2021-05-04 | |||
| CN109908143A | 2019-06-21 | |||
| CN200910223861A | 2009-11-24 | |||
| CN201610856945A | 2016-09-27 | |||
| CN201811550290A | 2018-12-18 | |||
| CN105960415A | 2016-09-21 | |||
| CN108601831A | 2018-09-28 | |||
| CN106963948A | 2017-07-21 | |||
| CN109893654A | 2019-06-18 |
Other References:
ZHOU YOU, FU CHAO, KONG YIDI, PAN DESI, WANG YANAN, HUANG SHENGJIAN, LI ZHIBIN, NING ZHIQIANG, LU XIANPING, SHAN SONG, XIN LIJUN: "Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models", ANTI-CANCER DRUGS, vol. 30, no. 9, 1 October 2019 (2019-10-01), US , pages 909 - 916, XP055911393, ISSN: 0959-4973, DOI: 10.1097/CAD.0000000000000791
YOU ZHOU, SONG SHAN, ZHI-BIN LI, LI-JUN XIN, DE-SI PAN, QIAN-JIAO YANG, YING-PING LIU, XU-PENG YUE, XIAO-RONG LIU, JI-ZHOU GAO, JI: "CS2164, a novel multi-target inhibitor against tumor angiogenesis, mitosis and chronic inflammation with anti-tumor potency", CANCER SCIENCE, vol. 108, no. 3, 1 March 2017 (2017-03-01), JP , pages 469 - 477, XP055737667, ISSN: 1347-9032, DOI: 10.1111/cas.13141
YOU ZHOU, SONG SHAN, ZHI-BIN LI, LI-JUN XIN, DE-SI PAN, QIAN-JIAO YANG, YING-PING LIU, XU-PENG YUE, XIAO-RONG LIU, JI-ZHOU GAO, JI: "CS2164, a novel multi-target inhibitor against tumor angiogenesis, mitosis and chronic inflammation with anti-tumor potency", CANCER SCIENCE, vol. 108, no. 3, 1 March 2017 (2017-03-01), JP , pages 469 - 477, XP055737667, ISSN: 1347-9032, DOI: 10.1111/cas.13141
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