Title:
USE OF COMPOUND IN DRUG FOR PREVENTING, TREATING, OR ALLEVIATING PAIN
Document Type and Number:
WIPO Patent Application WO/2020/010900
Kind Code:
A1
Abstract:
The present invention provides a use of a compound shown in Formula I/II in a drug for preventing, treating, or alleviating pain.
More Like This:
Inventors:
DUAN JIANXIN (CN)
LI ANRONG (US)
MENG FANYING (US)
DONALD JUNG (US)
LI ANRONG (US)
MENG FANYING (US)
DONALD JUNG (US)
Application Number:
PCT/CN2019/084604
Publication Date:
January 16, 2020
Filing Date:
April 26, 2019
Export Citation:
Assignee:
SHENZHEN ASCENTAWITS PHARMACEUTICAL TECH CO LTD (CN)
International Classes:
A61K31/04; A61K31/06; A61K31/664; A61P29/00; C07B55/00; C07C205/38; C07F9/22; C07F9/564
Domestic Patent References:
| WO2017087428A1 | 2017-05-26 | |||
| WO2016145092A1 | 2016-09-15 | |||
| WO2016161342A2 | 2016-10-06 | |||
| WO2017087428A1 | 2017-05-26 |
Foreign References:
| CN107530556A | 2018-01-02 | |||
| CN108136214A | 2018-06-08 | |||
| CN103827133A | 2014-05-28 | |||
| US5424424A | 1995-06-13 | |||
| US20160021581W | 2016-03-09 | |||
| US20160025665W | 2016-04-01 | |||
| US20160062114W | 2016-11-15 | |||
| CN201680015078A | 2016-03-09 | |||
| CN107530556A | 2018-01-02 | |||
| CN201680020013A | 2016-04-01 | |||
| CN108136214A | 2018-06-08 |
Other References:
SAMAD T AMOORE K ASAPIRSTEIN A ET AL.: "Interleukin-l[beta]-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity[J", NATURE, vol. 410, no. 6827, 2001, pages 471 - 5, XP002950813, DOI: 10.1038/35068566
BAOJIAN ZYANBING YGELE A ET AL.: "Tanshinone IIA Attenuates Diabetic Peripheral Neuropathic Pain in Experimental Rats via Inhibiting Inflammation[J", EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, vol. 2018, 2018, pages 1 - 8
LOVERING ARIDE JBUNCE C ET AL.: "Crystal Structures of Prostaglandin D 11-Ketoreductase (AKR1C3) in Complex with the Nonsteroidal Anti-Inflammatory Drugs Flufenamic Acid and Indomethacin[J", CANCER RESEARCH, vol. 64, no. 5, 2004, pages 1802 - 1810
MATSUURA KSHIRAISHI HHARA A ET AL.: "Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D 11-ketoreductase activity.[J", JOURNAL OF BIOCHEMISTRY, vol. 124, no. 5, 1998, pages 940 - 6
NOGRADY: "Medicinal Chemistry A Biochemical Approach", 1985, OXFORD UNIVERSITY PRESS, pages: 388 - 392
See also references of EP 3821884A4
BAOJIAN ZYANBING YGELE A ET AL.: "Tanshinone IIA Attenuates Diabetic Peripheral Neuropathic Pain in Experimental Rats via Inhibiting Inflammation[J", EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, vol. 2018, 2018, pages 1 - 8
LOVERING ARIDE JBUNCE C ET AL.: "Crystal Structures of Prostaglandin D 11-Ketoreductase (AKR1C3) in Complex with the Nonsteroidal Anti-Inflammatory Drugs Flufenamic Acid and Indomethacin[J", CANCER RESEARCH, vol. 64, no. 5, 2004, pages 1802 - 1810
MATSUURA KSHIRAISHI HHARA A ET AL.: "Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D 11-ketoreductase activity.[J", JOURNAL OF BIOCHEMISTRY, vol. 124, no. 5, 1998, pages 940 - 6
NOGRADY: "Medicinal Chemistry A Biochemical Approach", 1985, OXFORD UNIVERSITY PRESS, pages: 388 - 392
See also references of EP 3821884A4
Attorney, Agent or Firm:
SHANGHAI DANRONG & ZONGDE INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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