Title:
USE OF DIAMINOGUANIDINE DERIVATIVE AND FEED COMPOSITION THEREOF IN PREPARATION OF VETERINARY DRUG
Document Type and Number:
WIPO Patent Application WO/2021/012138
Kind Code:
A1
Abstract:
Disclosed is a use of a diaminoguanidine derivative and a feed composition thereof in the preparation of a veterinary drug. Particularly, disclosed is a use of a diaminoguanidine derivative having a structure of formula (I), or a stereoisomer, geometric isomer, tautomer, solvate, pharmaceutically acceptable salt thereof, or a prodrug thereof, in the preparation of an animal drug for preventing, managing, treating, or alleviating a disease resulting from bacterial infection, wherein R is NO 2, or a group represented by formula (II) or formula (III); R 1 is a linear or branched C 1-C 20 alkyl group; A is O, N or S; R 2 is a linear or branched C 3-C 14 alkyl, C 5-C 6 cycloalkyl, C 5-C 6 aryl or CH 2(C 5-C 6 aryl) group. The diaminoguanidine derivative is a non-toxic and safe compound for animals, and is markedly effective in the treatment of infectious diseases in the reproductive system, skin, etc., of farmed animals.
Inventors:
PENG XIANFENG (CN)
Application Number:
PCT/CN2019/096997
Publication Date:
January 28, 2021
Filing Date:
July 22, 2019
Export Citation:
Assignee:
GUANGZHOU INSIGHTER BIOTECHNOLOGY CO LTD (CN)
International Classes:
A61K31/155; C07C281/18
Foreign References:
| CN105579432A | 2016-05-11 | |||
| CN103880712A | 2014-06-25 | |||
| CN104744312A | 2015-07-01 | |||
| CN105030744A | 2015-11-11 |
Other References:
ABRAHAM, REBECCA J. ET AL.: "Robenidine Analogues as Gram-Positive Antibacterial Agents", JOURNAL OF MEDICINAL CHEMISTRY, vol. 59, no. 5, 14 January 2016 (2016-01-14), XP055739566, ISSN: 1520-4804, DOI: 20200306122533X
Attorney, Agent or Firm:
GUANGZHOU KEYUE I.P. LAW OFFICE (CN)
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