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Title:
USE OF ENZYME-MODIFIED ISOQUERCITRIN
Document Type and Number:
WIPO Patent Application WO/2017/094910
Kind Code:
A1
Abstract:
The present invention provides a salivation-stimulating agent which has a dosage form that can be used in the oral cavity or a dosage form that can be used through oral administration (a dosage form for use in the oral cavity, a dosage form for oral administration). The salivation-stimulating agent can be prepared using enzyme-modified isoquercitrin or a combination of enzyme-modified isoquercitrin and a thickening polysaccharide. The present invention also provides an additive (an additive for an oral composition) which is effective for the preparation of an oral composition (a food or beverage, a medicine for oral administration) and which can impart at least one activity selected from the group consisting of a salivation-stimulating activity, a swallowing-improving activity (a swallowing-assisting activity) and a mastication-improving activity (a mastication-assisting activity) to an oral composition. The additive can be prepared using a combination of enzyme-modified isoquercitrin and a thickening polysaccharide.

Inventors:
SATO, Hiroyuki (INC. 1-1-11, Sanwa-cho, Toyonaka-sh, Osaka 88, 〒5618588, JP)
NAKAUMA, Makoto (INC. 1-1-11, Sanwa-cho, Toyonaka-sh, Osaka 88, 〒5618588, JP)
IKEGAMI, Akira (INC. 1-1-11, Sanwa-cho, Toyonaka-sh, Osaka 88, 〒5618588, JP)
FUNAMI, Takahiro (INC. 1-1-11, Sanwa-cho, Toyonaka-sh, Osaka 88, 〒5618588, JP)
ORIKOSHI, Hideyuki (INC. 1-1-11, Sanwa-cho, Toyonaka-sh, Osaka 88, 〒5618588, JP)
Application Number:
JP2016/085980
Publication Date:
June 08, 2017
Filing Date:
December 02, 2016
Export Citation:
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Assignee:
SAN-EI GEN F.F.I., INC. (1-1-11, Sanwa-cho Toyonaka-sh, Osaka 88, 〒5618588, JP)
International Classes:
A23L33/10; A61K8/73; A61K31/7048; A61K47/36; A61P1/02; A61Q11/00
Domestic Patent References:
WO2009060915A12009-05-14
Foreign References:
JP2012085568A2012-05-10
JP2010270045A2010-12-02
JPH07101856A1995-04-18
JP2003040752A2003-02-13
JPH1171253A1999-03-16
JPH10182392A1998-07-07
JP2002265375A2002-09-18
JP2005162633A2005-06-23
JP2009531287A2009-09-03
JPH0812575A1996-01-16
JP2001064203A2001-03-13
Other References:
MASAMITSU MORIWAKI ET AL.: "Koketsuatsu Shizen Hassho Rat ni Okeru Koso Shori Isoquercitrin no Koka", PROCEEDINGS OF THE ANNUAL MEETING OF JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY 2007 NENDO(HEISEI 19 NENDO) TAIKAI, 3 May 2007 (2007-05-03), Tokyo, pages 281
TAMURA, S. ET AL.: "Metabolic behavior of enzymatically modified isoquercitrin by alpha- amylase and gastric juices", JAPANESE JOURNAL OF FOOD CHEMISTRY AND SAFETY, vol. 12, no. 3, 2005, pages 152 - 156, XP055496591
ICHIRO SAITO ET AL., PLOS ONE, 28 January 2015 (2015-01-28)
"Enzymatically Modified Isoquercitrin", THE MINISTRY OF HEALTH, LABOUR AND WELFARE, article "The Japanese Standards of Food Additives"
"Japanese Pharmaceutical Excipients Directory", YAKUJI NIPPO, LIMITED
"Specifications and Standards for Food Additives", THE MINISTRY OF HEALTH, LABOUR AND WELFARE, article "Enzymatically Modified Isoquercitrin"
"Enzymatically Modified Isoquercitrin", THE MINISTRY OF HEALTH, LABOUR AND WELFARE, article "Specifications and Standards for Food Additives"
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (Kitahama TNK Building, 1-7-1 Doshomachi, Chuo-ku, Osaka-sh, Osaka 45, 〒5410045, JP)
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