Title:
USE OF FORMULA OF PROBIOTICS AND METABOLITES (POSTBIOTICS) THEREOF IN PREPARATION OF PRODUCT FOR ALLEVIATING COLORECTAL INFLAMMATION
Document Type and Number:
WIPO Patent Application WO/2023/040422
Kind Code:
A1
Abstract:
The use of one or more strains of Lactobacillus reuteri PLBK®1, Lactobacillus reuteri PLBK®2, Lactobacillus gasseri PLBK®3, Lactobacillus acidophilus PLBK®4 and Bifidobacterium lactis PLBK®5 and fermentation cultures or metabolites thereof in the preparation of a product for alleviating colorectal inflammation. The use can reduce macrophage infiltration, reduce intestinal inflammation, regulate the microenvironment of intestinal flora and accelerate the repair of intestinal mucosa, and the formula is expected to be used in the clinical prevention and treatment of inflammatory bowel disease associated with colorectal inflammation.
Inventors:
XIE LIWEI (CN)
Application Number:
PCT/CN2022/103560
Publication Date:
March 23, 2023
Filing Date:
July 04, 2022
Export Citation:
Assignee:
INST OF MICROBIOLOGY GUANGDONG ACADEMY OF SCIENCES GUANGDONG DETECTION CENTER OF MICROBIOLOGY (CN)
International Classes:
C12N1/20; A23L33/135; A61K35/747; A61P1/16; A61P3/04; A61P5/50; C12R1/01; C12R1/225; C12R1/23
Domestic Patent References:
| WO2012089783A1 | 2012-07-05 |
Foreign References:
| CN114480228A | 2022-05-13 | |||
| CN113151056A | 2021-07-23 | |||
| CN109628358A | 2019-04-16 | |||
| CN110448577A | 2019-11-15 |
Other References:
ANONYMOUS: "Baiyunshan has launched three high-companion probiotics, and its five domestic strains have attracted attention", GLOBAL FORTUNE NETWORK, 24 September 2021 (2021-09-24), pages 1 - 2, XP093048307, Retrieved from the Internet [retrieved on 20230522]
Attorney, Agent or Firm:
GUANGZHOU KEYUE I.P. LAW OFFICE (CN)
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