Title:
USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER
Document Type and Number:
WIPO Patent Application WO/2024/026458
Kind Code:
A3
Abstract:
Disclosed herein is a method of treating cancer in a subject that includes administering to a subject having a cancer an inhibitor of glycogen metabolism under conditions effective to treat the cancer, wherein the cancer is characterized by cells having an increased glycogen expression or activity relative to corresponding non-cancer cells of similar origin. Further disclosed herein is a method of inhibiting tumor growth in a subject that includes administering to a subject having a tumor an inhibitor of glycogen metabolism under conditions effective to treat the tumor, wherein the tumor is characterized by cells having an increased glycogen expression or activity relative to corresponding non-tumor cells of similar origin. The present disclosure further relates to a combination therapy that includes an inhibitor of glycogen metabolism and a cancer therapeutic.
Inventors:
CARR FRANCES (US)
DAVIDSON COLE (US)
DAVIDSON COLE (US)
Application Number:
PCT/US2023/071213
Publication Date:
April 04, 2024
Filing Date:
July 28, 2023
Export Citation:
Assignee:
THE UNIV OF VERMONT (US)
International Classes:
A61P35/00; A61K31/519; A61K33/24
Attorney, Agent or Firm:
KEYS, Amanda, L. et al. (US)
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