USE OF IL-9 AS DRUG FOR TREATING THROMBOCYTOPENIA

WIPO Patent Application WO/2017/185434

A1

Provided is use of IL-9 in preparing drugs for treating thrombocytopenia and decreases in bone marrow megakaryocyte proliferation, and in particular, use of IL-9 in preparing drugs for treating drug-induced thrombocytopenia and decreases in bone marrow megakaryocyte proliferation, wherein the drugs are preferably anti-tumor chemotherapeutic drugs.

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BAI XIAOCHUN (CN)
XIAO MIN (CN)
WANG YONGKUI (CN)
TAO CHEN (CN)
CHEN ZHENGUO (CN)

PCT/CN2016/082728

November 02, 2017

May 20, 2016

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UNIV SOUTHERN MEDICAL (CN)

A61K38/20; A61P7/04

WO2008151386A1

2008-12-18

US20130136722A1

2013-05-30

LEI, HUIFEN ET AL.: "Research progress of Stem Cells Expansion in vitro into Megakaryocyte and Production of Blood Platelet", CHINESE JOURNAL OF BLOOD TRANSFUSION, vol. 24, no. 6, 30 June 2011 (2011-06-30), pages 534 - 538
PANUGANTI, SWAPNA: "Three-Stage Ex Vivo Expansion of High-Ploidy Megakaryocytic Cell :Toward Large-Scale Platelet Production", TISSUE ENGINEERING:PART A, vol. 19, no. 7-8, 9 January 2013 (2013-01-09), pages 998 - 1014, XP055601859, DOI: 10.1089/ten.TEA.2011.0111
FUJIKI, HIROSHI ET AL.: "Role of human interleukin-9 as a megakaryocyte potentiator in culture", EXPERIMENTAL HEMATOLOGY, vol. 30, no. 12, 31 December 2002 (2002-12-31), pages 1373 - 1380, XP055601863, DOI: 10.1016/S0301-472X(02)00966-9

BEIJING CHENGHUI LAW FIRM (CN)

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