Title:
USE OF INHIBITING ACTIVITY OF CASEIN KINASE 2 FOR ENHANCING EXPRESSION OF TYPE I INTERFERON
Document Type and Number:
WIPO Patent Application WO/2016/050203
Kind Code:
A1
Abstract:
A use of a casein kinase 2 inhibitor in preparing a pharmaceutical composition for enhancing the expression of type I interferon and/or a type I interferon-induced gene or a protein thereof; and/or in preparing a pharmaceutical composition for treating and/or preventing the diseases related to the lack of type I interferon.
Inventors:
XIAO HUI (CN)
DU MIN (CN)
LIU JINGHUA (CN)
XIE YADONG (CN)
ZHONG JING (CN)
XIANG YU (CN)
DU MIN (CN)
LIU JINGHUA (CN)
XIE YADONG (CN)
ZHONG JING (CN)
XIANG YU (CN)
Application Number:
PCT/CN2015/091111
Publication Date:
April 07, 2016
Filing Date:
September 29, 2015
Export Citation:
Assignee:
INST PASTEUR SHANGHAI CAS (CN)
International Classes:
A61K45/00; A61K39/395; A61K48/00; A61P25/28; A61P31/12; A61P35/00; A61P35/02; C12P21/02; G01N33/68
Foreign References:
| CN1857259A | 2006-11-08 |
Other References:
LIU, M. ET AL.: "Discovery of Flavonoid Derivatives as anti-HCV Agents via Pharmacophore Search Combining Molecular Docking Strategy", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 52, 30 June 2012 (2012-06-30), ISSN: 0223-5234
LIU, CHAO ET AL.: "Effect of Tetrabromophthalic Triazole on Cell Apoptosis of Thyroid Gland Squamous Carcinoma SW579", CHINESE JOURNAL OF GERONTOLOGY, vol. 33, no. 1, 31 January 2013 (2013-01-31), ISSN: 1005-9202
YAO, KAI ET AL.: "Tetrabromocinnamic Acid Reduces Cell Proliferation and Causes Cell Cycle Arrest in Prostate Cancer Cells", JOURNAL OF MODERN UROLOGY, vol. 18, no. 6, 30 November 2013 (2013-11-30), ISSN: 1009-8291
SMITH, M.C. ET AL.: "CK2 Inhibitors Increase the Sensitivity of HSV-1 to Interferon-p", ANTIVIRAL RESEARCH, vol. 91, no. 3, 30 September 2011 (2011-09-30), XP028267508, ISSN: 0166-3542, DOI: doi:10.1016/j.antiviral.2011.06.009
LIU, CHAO ET AL.: "Effect of Tetrabromophthalic Triazole on Cell Apoptosis of Thyroid Gland Squamous Carcinoma SW579", CHINESE JOURNAL OF GERONTOLOGY, vol. 33, no. 1, 31 January 2013 (2013-01-31), ISSN: 1005-9202
YAO, KAI ET AL.: "Tetrabromocinnamic Acid Reduces Cell Proliferation and Causes Cell Cycle Arrest in Prostate Cancer Cells", JOURNAL OF MODERN UROLOGY, vol. 18, no. 6, 30 November 2013 (2013-11-30), ISSN: 1009-8291
SMITH, M.C. ET AL.: "CK2 Inhibitors Increase the Sensitivity of HSV-1 to Interferon-p", ANTIVIRAL RESEARCH, vol. 91, no. 3, 30 September 2011 (2011-09-30), XP028267508, ISSN: 0166-3542, DOI: doi:10.1016/j.antiviral.2011.06.009
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
上海一平知识产权代理有限公司 (CN)
上海一平知识产权代理有限公司 (CN)
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