Title:
Use of linalool synthase in genetic engineering ofscent production
Document Type and Number:
WIPO Patent Application WO1997015584
Kind Code:
A3
Abstract:
A purified S-linalool synthase polypeptide from Clarkia breweri is disclosed as is the recombinant polypeptide and nucleic acid sequences encoding the polypeptide. Also disclosed are antibodies immunoreactive with the purified peptide and with recombinant versions of the polypeptide. Methods of using the nucleic acid sequences, as well as methods of enhancing the smell and the flavor of plants expressing the nucleic acid sequences are also disclosed.
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Inventors:
PICHERSKY ERAN (US)
Application Number:
PCT/US1996/016482
Publication Date:
September 25, 1997
Filing Date:
October 15, 1996
Export Citation:
Assignee:
UNIV MICHIGAN (US)
PICHERSKY ERAN (US)
PICHERSKY ERAN (US)
International Classes:
C12N9/00; C12N15/82; (IPC1-7): C12N15/52; A01H5/00; C07K16/40; C12N1/21; C12N15/82
Domestic Patent References:
| WO1995011913A1 | 1995-05-04 | |||
| WO1992016611A1 | 1992-10-01 | |||
| WO1992006206A1 | 1992-04-16 | |||
| WO1993007257A2 | 1993-04-15 |
Other References:
MCGARVEY, D.J., ET AL.: "Terpenoid metabolism", THE PLANT CELL, vol. 7, no. 7, July 1995 (1995-07-01), pages 1015 - 1026, XP002036386
MOL J N M ET AL: "FLORICULTURE: GENETIC ENGINEERING OF COMMERCIAL TRAITS", TRENDS IN BIOTECHNOLOGY, vol. 13, no. 9, September 1995 (1995-09-01), pages 350 - 355, XP002024912
CHEMICAL ABSTRACTS, vol. 122, no. 15, 10 April 1995, Columbus, Ohio, US; abstract no. 181648, PICHERSKY, ERAN ET AL: "Purification and characterization of S-linalool synthase, an enzyme involved in the production of floral scent in Clarkia breweri" XP002036391
DUDAREVA N ET AL: "Evolution of floral scent in Clarkia: Novel patterns of S-linalool synthase gene expression in the C. breweri flower.", PLANT CELL 8 (7). 1996. 1137-1148., July 1996 (1996-07-01), XP002036387
PICHERSKY E ET AL: "Floral Scent Production in Clarkia (Onagraceae): I. Localization and Developmental Modulation of Monoterpene Emission and Linalool Synthase Activity.", PLANT PHYSIOLOGY (ROCKVILLE) 106 (4). 1994. 1533-1540., XP002036388
COLBY, S.M., ET AL.: "4S-limonene synthase from the oil glands of spearmint (Mentha spicata)", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 268, no. 31, 1993, pages 23016 - 23024, XP002036389
CHEMICAL ABSTRACTS, vol. 118, no. 23, 7 June 1993, Columbus, Ohio, US; abstract no. 230249, SPENCER, ANDREW ET AL: "In vitro biosynthesis of monoterpenes by Agrobacterium transformed shoot cultures of two Mentha species" XP002036392
PELLEGRINESCHI, A., ET AL.: "Improvement of ornamental characters and fragrance production in lemon-scented geranium through genetic transformation by Agrobacterium rhizogenes", BIOTECHNOLOGY, vol. 12, no. 1, January 1994 (1994-01-01), pages 64, XP002036390
MOL J N M ET AL: "FLORICULTURE: GENETIC ENGINEERING OF COMMERCIAL TRAITS", TRENDS IN BIOTECHNOLOGY, vol. 13, no. 9, September 1995 (1995-09-01), pages 350 - 355, XP002024912
CHEMICAL ABSTRACTS, vol. 122, no. 15, 10 April 1995, Columbus, Ohio, US; abstract no. 181648, PICHERSKY, ERAN ET AL: "Purification and characterization of S-linalool synthase, an enzyme involved in the production of floral scent in Clarkia breweri" XP002036391
DUDAREVA N ET AL: "Evolution of floral scent in Clarkia: Novel patterns of S-linalool synthase gene expression in the C. breweri flower.", PLANT CELL 8 (7). 1996. 1137-1148., July 1996 (1996-07-01), XP002036387
PICHERSKY E ET AL: "Floral Scent Production in Clarkia (Onagraceae): I. Localization and Developmental Modulation of Monoterpene Emission and Linalool Synthase Activity.", PLANT PHYSIOLOGY (ROCKVILLE) 106 (4). 1994. 1533-1540., XP002036388
COLBY, S.M., ET AL.: "4S-limonene synthase from the oil glands of spearmint (Mentha spicata)", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 268, no. 31, 1993, pages 23016 - 23024, XP002036389
CHEMICAL ABSTRACTS, vol. 118, no. 23, 7 June 1993, Columbus, Ohio, US; abstract no. 230249, SPENCER, ANDREW ET AL: "In vitro biosynthesis of monoterpenes by Agrobacterium transformed shoot cultures of two Mentha species" XP002036392
PELLEGRINESCHI, A., ET AL.: "Improvement of ornamental characters and fragrance production in lemon-scented geranium through genetic transformation by Agrobacterium rhizogenes", BIOTECHNOLOGY, vol. 12, no. 1, January 1994 (1994-01-01), pages 64, XP002036390
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