Title:
USE OF PAROXETINE FOR THE TREATMENT OF SENILE DEMENTIA, BULIMIA, MIGRAINE OR ANOREXIA
Document Type and Number:
WIPO Patent Application WO1992009281
Kind Code:
A3
Abstract:
PCT No. PCT/GB91/02062 Sec. 371 Date May 21, 1993 Sec. 102(e) Date May 21, 1993 PCT Filed Nov. 21, 1991 PCT Pub. No. WO92/09281 PCT Pub. Date Jun. 11, 1992.The method of using paroxetine or a pharmaceutically acceptable salt thereof for the treatment of senile dementia.
Inventors:
JOHNSON ANTHONY MICHAEL (GB)
Application Number:
PCT/GB1991/002062
Publication Date:
October 01, 1992
Filing Date:
November 21, 1991
Export Citation:
Assignee:
BEECHAM GROUP PLC (GB)
International Classes:
A61K31/4427; A61K31/445; A61P3/04; A61P25/04; A61P25/06; A61P25/28; C07D401/12; (IPC1-7): A61K31/445
Foreign References:
| US4007196A | 1977-02-08 | |||
| EP0188081A2 | 1986-07-23 | |||
| EP0226574A1 | 1987-07-01 |
Other References:
International Journal of Geriatric Psychiatry, vol. 3, 1988, John Wiley & Sons, Ltd, J. BALLDIN et al.: "Relationship between DST and the serotonergic system. Results from treatments with two 5-HT reuptake blockers in dementia disorders", pages 17-26, see page 18, column 2, lines 15-39; page 19, column 2, lines 25-38
Annals of the New York Academy of Sciences, vol. 600, October 1990, (New York, US), A.J. CROSS: "Serotonin in Alzheimer-type dementia and other dementing illnesses", pages 405-417, see page 406, table 1; pages 412-413
Current Therapeutic Research, vol. 25, no. 2, February 1979, E. SYVÄLAHTI et al.: "Migraine headache and blood serotonin levels after administration of zimelidine, a selective inhibitor of serotonin uptake", pages 299-310, see the whole document
Progress in Drug Research, vol. 35, 1990, (Basel, CH), R.W. FULLER: "Drugs affecting serotonin neurons", pages 85-108, see page 87, paragraph 3 - page 88; page 89, paragraph 9; page 99, paragraph 2
European Journal of Pharmacology, vol. 183, no. 5, July 1990, M.D. COTRIM et al.: "Migraine and serotonin uptake, 3Hdelta-paroxetine and 3H-imipramine binding", page 1917, see the whole document
Acta Psychiatrica Scandinavica, vol. 80, suppl. 350, 1989, S.A. MONTGOMERY: "New antidepressants and 5-HT uptake inhibitors", pages 107-116, see page 108, column 2, paragraph 2; page 114, column 1, last paragraph
International Journal of Obesity, vol. 11, suppl. 3, December 1987, C.P.L. FREEMAN et al.: "Fluoxetine as a treatment for bulimia nervosa", pages 171-177, see the whole document
American Journal of Psychiatry, vol. 146, June 1989, E. HOLLANDER et al.: "Treatment of body-dysmorphic disorder with serotonin reuptake blockers", pages 768-770, see the whole document
Annals of the New York Academy of Sciences, vol. 600, October 1990, (New York, US), A.J. CROSS: "Serotonin in Alzheimer-type dementia and other dementing illnesses", pages 405-417, see page 406, table 1; pages 412-413
Current Therapeutic Research, vol. 25, no. 2, February 1979, E. SYVÄLAHTI et al.: "Migraine headache and blood serotonin levels after administration of zimelidine, a selective inhibitor of serotonin uptake", pages 299-310, see the whole document
Progress in Drug Research, vol. 35, 1990, (Basel, CH), R.W. FULLER: "Drugs affecting serotonin neurons", pages 85-108, see page 87, paragraph 3 - page 88; page 89, paragraph 9; page 99, paragraph 2
European Journal of Pharmacology, vol. 183, no. 5, July 1990, M.D. COTRIM et al.: "Migraine and serotonin uptake, 3Hdelta-paroxetine and 3H-imipramine binding", page 1917, see the whole document
Acta Psychiatrica Scandinavica, vol. 80, suppl. 350, 1989, S.A. MONTGOMERY: "New antidepressants and 5-HT uptake inhibitors", pages 107-116, see page 108, column 2, paragraph 2; page 114, column 1, last paragraph
International Journal of Obesity, vol. 11, suppl. 3, December 1987, C.P.L. FREEMAN et al.: "Fluoxetine as a treatment for bulimia nervosa", pages 171-177, see the whole document
American Journal of Psychiatry, vol. 146, June 1989, E. HOLLANDER et al.: "Treatment of body-dysmorphic disorder with serotonin reuptake blockers", pages 768-770, see the whole document
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