USE OF PTERIDINONE DERIVATIVE SERVING AS EGFR INHIBITOR

Title:

USE OF PTERIDINONE DERIVATIVE SERVING AS EGFR INHIBITOR

Document Type and Number:

WIPO Patent Application WO/2016/192609

Kind Code:

A1

Abstract:

The present invention relates to a pteridinone derivative serving as an EGFR inhibitor and use thereof. Specifically, the present invention relates to a compound represented by the following formula I, pharmaceutical composition comprising the compound of the following formula I, and use of the compound in preparation of drugs for treating EGFR-mediated diseases or inhibiting EGFR.

More Like This:

WO/2020/033823	SMALL-MOLECULE PI5P4K ALPHA/BETA INHIBITORS AND METHODS OF TREATMENT USING SAME
JP3599287	SULFONAMIDE DERIVATIVE
JP2013505927	Method for preparing pyrimidine derivative useful as a protein kinase inhibitor

Inventors:

LI HONGLIN (CN)
XU YUFANG (CN)
ZHAO ZHENJIANG (CN)
ZHOU WEI (CN)
XU YUQIONG (CN)
SUN DEHENG (CN)
WANG XIA (CN)
CHEN ZHUO (CN)

Application Number:

PCT/CN2016/083945

Publication Date:

December 08, 2016

Filing Date:

May 30, 2016

Export Citation:

Click for automatic bibliography generation Help

Assignee:

UNIV EAST CHINA SCIENCE & TECH (CN)

International Classes:

C07D475/00; A61K31/519; A61P35/00; A61P35/02

Domestic Patent References:

WO2006002367A1	2006-01-05
WO2013170671A1	2013-11-21

Foreign References:

CN1373763A

2002-10-09

Other References: