Title:
USE OF PYRIDOXIN DERIVATIVES FOR THE TREATMENT OF DIABETES AND RELATED COMPLICATIONS
Document Type and Number:
WIPO Patent Application WO2001003682
Kind Code:
B1
Abstract:
Methods for treating diabetes mellitus and related conditions and symptoms are described. The methods are directed to administering a therapeutically effective amount of a compound. Compounds suitable for the invention include pyridoxal-5'-phosphate, pyridoxal, pyridoxamine, pyridoxine, a 3-acylated pyridoxal analogue, a pharmaceutically acceptable acid addition salt thereof, or a mixture thereof. Also disclosed are methods directed to concurrently administering a therapeutically effective amount of a compound with other compounds known in the treatment of diabetes mellitus. In one embodiment, a therapeutically effective amount of a compound is administered concurrently with a therapeutically effective amount of insulin. In another embodiment, a therapeutically effective amount of a compound is administered concurrently with a therapeutically effective amount of a hypoglycemic compound.
Inventors:
SETHI RAJAT
HAQUE WASIMUL
HAQUE WASIMUL
Application Number:
PCT/IB2000/001041
Publication Date:
January 24, 2002
Filing Date:
July 13, 2000
Export Citation:
Assignee:
MEDICURE INC (CA)
International Classes:
A61K31/435; A61K31/4355; A61K31/44; A61K31/4415; A61K31/5375; A61K31/64; A61K31/675; A61K31/715; A61K45/06; (IPC1-7): A61K31/4415; A61K31/675; A61P3/10
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