Title:
USE OF RESVERATROL IN CELL ELECTROTRANSFECTION AND ELECTROTRANSFECTION SOLUTION
Document Type and Number:
WIPO Patent Application WO/2022/135584
Kind Code:
A1
Abstract:
The present invention belongs to the technical field of biology. Specifically disclosed is the use of resveratrol in cell electrotransfection, and further disclosed are an electrotransfection solution containing resveratrol and a method for cell electrotransfection. By means of the present invention, resveratrol is added to electrotransfected cells, and tests prove that the electrotransfection efficiency of fibroblasts can be improved, and the objective of improving the electrotransfection efficiency without influencing cell growth can be achieved. Resveratrol is naturally harmless, is safe to cells, and provides a safeguard for the use thereof in the birth of transgenic animals.
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Inventors:
LIU GUOSHI (CN)
YAO YUJUN (CN)
LI GUANGDONG (CN)
WU HAO (CN)
ZHANG LU (CN)
LIAN ZHENGXING (CN)
LV DONGYING (CN)
YAO YUJUN (CN)
LI GUANGDONG (CN)
WU HAO (CN)
ZHANG LU (CN)
LIAN ZHENGXING (CN)
LV DONGYING (CN)
Application Number:
PCT/CN2021/141333
Publication Date:
June 30, 2022
Filing Date:
December 24, 2021
Export Citation:
Assignee:
UNIV CHINA AGRICULTURAL (CN)
International Classes:
C12N15/85
Foreign References:
| CN112725377A | 2021-04-30 | |||
| EP2192174A1 | 2010-06-02 |
Other References:
KON EDO, HAZAN-HALEVY INBAL, ROSENBLUM DANIEL, COHEN NIV, CHATTERJEE SUSHMITA, VEIGA NUPHAR, RAANANI PIA, BAIREY OSNAT, BENJAMINI : "Resveratrol Enhances mRNA and siRNA Lipid Nanoparticles Primary CLL Cell Transfection", PHARMACEUTICS, vol. 12, no. 6, pages 520, XP055945190, DOI: 10.3390/pharmaceutics12060520
Attorney, Agent or Firm:
IPSUNNY (CN)
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