Title:
USE OF SHP2 INHIBITOR FOR TREATING TUMORS CONTAINING RAS PATHWAY GENE MUTATIONS
Document Type and Number:
WIPO Patent Application WO/2023/025290
Kind Code:
A1
Abstract:
A use of an SHP2 inhibitor for treating tumors containing RAS pathway gene mutations. Specifically, the present invention relates to the use of a compound as shown in formula (I) or a pharmaceutically acceptable salt thereof in the preparation of a drug for the treatment of tumors containing RAS pathway gene mutations.
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Inventors:
TIAN YUNAN (CN)
FU QIANG (CN)
LIN KAN (CN)
ZHANG XIAOJING (CN)
ZHANG LEI (CN)
YANG CHANGYONG (CN)
LIAO CHENG (CN)
SHI WEI (CN)
FU QIANG (CN)
LIN KAN (CN)
ZHANG XIAOJING (CN)
ZHANG LEI (CN)
YANG CHANGYONG (CN)
LIAO CHENG (CN)
SHI WEI (CN)
Application Number:
PCT/CN2022/115167
Publication Date:
March 02, 2023
Filing Date:
August 26, 2022
Export Citation:
Assignee:
JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN)
SHANGHAI SHENGDI PHARMACEUTICAL CO LTD (CN)
SHANGHAI SHENGDI PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D487/04; A61K31/519; A61P35/00; C07D519/00
Domestic Patent References:
| WO2020094104A1 | 2020-05-14 | |||
| WO2020072656A1 | 2020-04-09 | |||
| WO2020259679A1 | 2020-12-30 | |||
| WO2020108590A1 | 2020-06-04 |
Foreign References:
| CN113754683A | 2021-12-07 |
Other References:
BIAN YUNYI, YANG XIAO-DONG; ZHAN CHENG; YAO GUANG-YU; BI GUO-SHU; FAN HONG: "Progress in Pharmacological Strategies Targeting KRAS Gene Mutated Cancers", FUDAN XUEBAO (YIXUE BAN) /, FUDAN UNIVERSITY MEDICAL SCIENCES. JOURNAL (MEDICAL SCIENCE), CN, vol. 47, no. 3, 25 May 2020 (2020-05-25), CN , pages 439 - 455, XP093039883, ISSN: 1672-8467, DOI: 10.3969/j.issn.1672-8467.2020.03.021
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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