USE OF STABLE GLUTAMINE DERIVATIVES TO IMPROVE DRUG ABSORPTION

Title:

USE OF STABLE GLUTAMINE DERIVATIVES TO IMPROVE DRUG ABSORPTION

Document Type and Number:

WIPO Patent Application WO2004033484

Kind Code:

A3

Abstract:

The present invention relates to compositions and their use to enhance the uptake of pharmaceutical agents administered to mammalian species, including humans. More particularly, the present invention is directed to the administration of glutamine and stabilized glutamine derivatives to enhance the uptake of orally administered therapeutic agents.

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Inventors:

GUERRANT RICHARD L (US)
THIELMAN NATHAN M (US)
BRITO GERLY ANNE DE CASTRO (BR)
LIMA ALDO A M (BR)

Application Number:

PCT/US2003/032379

Publication Date:

June 10, 2004

Filing Date:

October 10, 2003

Export Citation:

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Assignee:

UNIV VIRGINIA (US)
GUERRANT RICHARD L (US)
THIELMAN NATHAN M (US)
BRITO GERLY ANNE DE CASTRO (BR)
LIMA ALDO A M (BR)

International Classes:

A61K9/00; A61K31/198; A61K38/02; A61K45/06; A61K47/18; (IPC1-7): A61K38/00

Domestic Patent References:

WO1999043708A1	1999-09-02
WO1996041181A1	1996-12-19

Foreign References:

US6262019B1

2001-07-17

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