Title:
USE OF TRADITIONAL CHINESE MEDICINE COMPOSITION IN PREPARATION OF DRUG FOR TREATING COUGH VARIANT ASTHMA
Document Type and Number:
WIPO Patent Application WO/2023/274150
Kind Code:
A1
Abstract:
A traditional Chinese medicine composition, prepared from Herba Schizonepetae, Root of Divaricate Saposhnikovia, Radix Et Rhizoma Notopterygii, Radix Angelicae Pubescentis, Root of Chinese Thorowax, Root of Grand Hogfennel, Rhizoma Chuanxiong, Fruit of Seville Orange, Poria, Platycodon Root, and Root of Ural Licorice. The traditional Chinese medicine composition can reduce the number of coughs of a guinea pig model of cough variant asthma, reduce an eosinophil percentage in bronchoalveolar lavage fluid, reduce a serum eosinophil cationic protein level, and has a prevention and treatment effect on cough variant asthma.
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Inventors:
ZHANG GUIMIN (CN)
LI XIN (CN)
LIU DONGGAUNG (CN)
LI XIN (CN)
LIU DONGGAUNG (CN)
Application Number:
PCT/CN2022/101536
Publication Date:
January 05, 2023
Filing Date:
June 27, 2022
Export Citation:
Assignee:
SHANDONG NEW TIME PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K36/75; A61K36/076; A61K36/23; A61K36/232; A61K36/233; A61K36/236; A61K36/237; A61K36/238; A61K36/34; A61K36/484; A61K36/538; A61P11/06
Foreign References:
| CN112386635A | 2021-02-23 | |||
| CN104784655A | 2015-07-22 | |||
| CN106728196A | 2017-05-31 | |||
| CN105396114A | 2016-03-16 | |||
| CN105816555A | 2016-08-03 | |||
| CN109010501A | 2018-12-18 | |||
| CN104288295A | 2015-01-21 |
Other References:
YANG DEYI: "Treating 57 Cases of Cough Variant Asthma with Herba ephedrae and Radix Ephedrae Combined Herba Schizonepetae and Radix Saposhnikoviae Toxin-Vanquishing Powder, [J", JIANGXI JOURNAL OF TRADITIONAL CHINESE MEDICINE, no. 7, 2006, pages 32
WANG XINXIAO NONGZHOU JIANGBAO: "Side Effects of Ephedrine and Related Research Status, [J", FOREIGN MEDICINE: FASCICULE OF TRADITIONAL CHINESE MEDICINE, vol. 27, no. 3, 2005, pages 155 - 156
LIU XIAOSHUAIZENG NANLIANG KEZHAO LUQU LIPINGSONG MEIFANGZHANG CHONGYAN: "Experiment Research on Anti-Inflammatory Mechanism of Nitric Oxide Synthase-Nitric Oxide Pathway Intervened by Herba Schizonepetae and Radix Saposhnikoviae Powder, [J", LISHIZHEN MEDICINE AND MATERIA MEDICA RESEARCH, vol. 19, no. 12, 2008, pages 3014 - 3015
YANG DEYI, JIANGXI JOURNAL OF TRADITIONAL CHINESE MEDICINE, vol. Treating 57 Cases of Cough Variant Asthma with Her, no. 7, 2006, pages 32 - 32
WANG XINXIAO NONGZHOU JIANGBAO: "Side Effects of Ephedrine and Related Research Status, [J", FOREIGN MEDICINE: FASCICULE OF TRADITIONAL CHINESE MEDICINE, vol. 27, no. 3, 2005, pages 155 - 156
LIU XIAOSHUAIZENG NANLIANG KEZHAO LUQU LIPINGSONG MEIFANGZHANG CHONGYAN: "Experiment Research on Anti-Inflammatory Mechanism of Nitric Oxide Synthase-Nitric Oxide Pathway Intervened by Herba Schizonepetae and Radix Saposhnikoviae Powder, [J", LISHIZHEN MEDICINE AND MATERIA MEDICA RESEARCH, vol. 19, no. 12, 2008, pages 3014 - 3015
YANG DEYI, JIANGXI JOURNAL OF TRADITIONAL CHINESE MEDICINE, vol. Treating 57 Cases of Cough Variant Asthma with Her, no. 7, 2006, pages 32 - 32
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