Title:
THE USE OF TRANSPORTERS TO MODULATE FLAVOR PRODUCTION BY YEAST
Document Type and Number:
WIPO Patent Application WO/2011/151326
Kind Code:
A3
Abstract:
The present invention relates to the use of transporters to modulate production of flavor and metabolically related compounds by yeast. More specifically, it related to the use of transporters of the ATP binding cassette (ABC) transporter family, the oligopeptide transporter (OPT) superfamily or the Major Facilitator Superfamily (MFS) to increase or decrease secondary metabolites linked to the isoleucine / valine pathway, such as, but not limited to α-acetolactate, diacetyl, pentanedione, iso-butyl alcohol, iso-amyl alcohol and isoamyl acetate.
Inventors:
THEVELEIN JOHAN (BE)
SAERENS SOFIE (BE)
SAERENS SOFIE (BE)
Application Number:
PCT/EP2011/058949
Publication Date:
February 28, 2013
Filing Date:
May 31, 2011
Export Citation:
Assignee:
VIB VZW (BE)
UNIV LEUVEN KATH (BE)
THEVELEIN JOHAN (BE)
SAERENS SOFIE (BE)
UNIV LEUVEN KATH (BE)
THEVELEIN JOHAN (BE)
SAERENS SOFIE (BE)
International Classes:
A23L27/24; C12P7/16; C07K14/395; C12C12/00
Domestic Patent References:
| WO1999051746A1 | 1999-10-14 |
Foreign References:
| US6326184B1 | 2001-12-04 | |||
| EP0574941A2 | 1993-12-22 | |||
| US20090148555A1 | 2009-06-11 |
Other References:
DATABASE WPI Week 200118, Derwent World Patents Index; AN 2001-172215, XP002689125
LUCIE A. HAZELWOOD ET AL: "A new physiological role for Pdr12p in Saccharomyces cerevisiae : export of aromatic and branched-chain organic acids produced in amino acid catabolism", FEMS YEAST RESEARCH, vol. 6, no. 6, 1 September 2006 (2006-09-01), pages 937 - 945, XP055047481, ISSN: 1567-1356, DOI: 10.1111/j.1567-1364.2006.00094.x
DANIEL VAN BELLE ET AL: "A genomic view of yeast membrane transporters", CURRENT OPINION IN CELL BIOLOGY, vol. 13, 1 January 2001 (2001-01-01), pages 389 - 398, XP055047658
S KANAZAWA ET AL: "ATR1, a Saccharomyces cerevisiae gene encoding a transmembrane protein required for aminotriazole resistance.", MOLECULAR AND CELLULAR BIOLOGY, vol. 8, no. 2, 1 January 1988 (1988-01-01), pages 664 - 673, XP055047759, DOI: 10.1128/MCB.8.2.664
See also references of EP 2575499A2
LUCIE A. HAZELWOOD ET AL: "A new physiological role for Pdr12p in Saccharomyces cerevisiae : export of aromatic and branched-chain organic acids produced in amino acid catabolism", FEMS YEAST RESEARCH, vol. 6, no. 6, 1 September 2006 (2006-09-01), pages 937 - 945, XP055047481, ISSN: 1567-1356, DOI: 10.1111/j.1567-1364.2006.00094.x
DANIEL VAN BELLE ET AL: "A genomic view of yeast membrane transporters", CURRENT OPINION IN CELL BIOLOGY, vol. 13, 1 January 2001 (2001-01-01), pages 389 - 398, XP055047658
S KANAZAWA ET AL: "ATR1, a Saccharomyces cerevisiae gene encoding a transmembrane protein required for aminotriazole resistance.", MOLECULAR AND CELLULAR BIOLOGY, vol. 8, no. 2, 1 January 1988 (1988-01-01), pages 664 - 673, XP055047759, DOI: 10.1128/MCB.8.2.664
See also references of EP 2575499A2
Attorney, Agent or Firm:
VIB VZW (Gent, BE)
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