USE OF TYROSINE KINASE INHIBITORS FOR TREATING SUBSTANCE USE DISORDERS

Title:

USE OF TYROSINE KINASE INHIBITORS FOR TREATING SUBSTANCE USE DISORDERS

Document Type and Number:

WIPO Patent Application WO2003072106

Kind Code:

A8

Abstract:

The present invention relates to a method for treating substance use disorders, more particularly drug addiction, drug habituation, drug dependence, withdrawal syndrome and overdose, comprising administering a compound capable of depleting mast cells to a human in need of such treatment. Such compounds can be chosen from tyrosine kinase inhibitors and more particularly non-toxic, selective and potent c-kit inhibitors. Preferably, said inhibitor is unable to promote death of IL-3 dependent cells cultured in presence of IL-3.

Inventors:

MOUSSY ALAIN (FR)
KINET JEAN-PIERRE (US)

Application Number:

PCT/IB2003/001071

Publication Date:

October 07, 2004

Filing Date:

February 26, 2003

Export Citation:

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Assignee:

AB SCIENCE (FR)
MOUSSY ALAIN (FR)
KINET JEAN-PIERRE (US)

International Classes:

A61K31/404; A61K31/505; A61K31/506; A61K31/517; A61K45/00; A61P25/30; C07D401/04; G01N33/15; G01N33/50; G01N33/53; (IPC1-7): A61K31/505; A61K31/404; A61K31/517; A61P25/30

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