USE OF TYRPHOSTINS TO STIMULATE NEURITE OUTGROWTH

Title:

USE OF TYRPHOSTINS TO STIMULATE NEURITE OUTGROWTH

Document Type and Number:

WIPO Patent Application WO2006031314

Kind Code:

A3

Abstract:

Disclosed herein are several methods for promoting nerve regeneration. The methods include administering at least one tyrphostin, or a pharmaceutically acceptable salt thereof. In one non-limiting example, the tyrphostin is tyrphostin A9. These methods can be used to promote nerve growth in the central or peripheral nervous system. The methods are of use in treating neurodegenerative diseases, such as Parkinson's disease, or in treating the transaction of a partial or complete transaction of a nerve in the peripheral or central nervous system.

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Inventors:

WANG CHUNHE (US)
GOLD BRUCE G (US)
NEVE KIM A (US)
ZHONG YONG-PING (US)
YU XIAOLIN (US)
JOHNSON ROBERT A (US)

Application Number:

PCT/US2005/028027

Publication Date:

November 02, 2006

Filing Date:

August 04, 2005

Export Citation:

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Assignee:

UNIV OREGON HEALTH & SCIENCE (US)
US GOV VETERANS AFFAIRS (US)
WANG CHUNHE (US)
GOLD BRUCE G (US)
NEVE KIM A (US)
ZHONG YONG-PING (US)
YU XIAOLIN (US)
JOHNSON ROBERT A (US)

International Classes:

A61K31/275; A01N37/34

Foreign References:

US6294346B1	2001-09-25
US6004791A	1999-12-21

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