USE OF VCAM-1+ MONOCYTE AND DERIVED CELL THEREOF IN PROMOTING HEMATOPOIETIC STEM CELLS HOMING

Title:

USE OF VCAM-1+ MONOCYTE AND DERIVED CELL THEREOF IN PROMOTING HEMATOPOIETIC STEM CELLS HOMING

Document Type and Number:

WIPO Patent Application WO/2018/196566

Kind Code:

A1

Abstract:

Provided in the present invention is the use of VCAM-1+ monocytes and derived cells thereof in promoting hematopoietic stem cells homing. In particular, provided in the present invention is a composition or a preparation promoting hematopoietic stem cells homing. Also provided in the present invention is a method for determining a potential therapeutic agent promoting hematopoietic stem cells homing.

Inventors:

PAN WEIJUN (CN)
LI DANTONG (CN)
XUE WENZHI (CN)
LI MEI (CN)

Application Number:

PCT/CN2018/081682

Publication Date:

November 01, 2018

Filing Date:

April 03, 2018

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Assignee:

SHANGHAI INST BIOLOGICAL SCIENCES CAS (CN)

International Classes:

C12N5/00; A61K35/14; A61P35/02; C12N5/071; C12N5/0786

Foreign References:

US20110091429A1	2011-04-21
CN105431521A	2016-03-23
CN103784940A	2014-05-14

Attorney, Agent or Firm:

XU AND PARTNERS, LLC. (CN)

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