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Title:
USES OF DNA TETRAHEDRON FOR INHIBITING ALZHEIMER'S DISEASE
Document Type and Number:
WIPO Patent Application WO/2019/100727
Kind Code:
A1
Abstract:
Disclosed are uses of a DNA tetrahedron for inhibiting Alzheimer's disease. Sequences of the four single-stranded DNA tetrahedron are shown as in SEQ ID NO: 1-4. Such uses can effectively inhibit cell apoptosis, and improve cell activity.

Inventors:
LIN, Yunfeng (No.24 in South Part of First Ring Road, Wuhou DistrictChengdu, Sichuan 4, 610064, CN)
SHAO, Xiaoru (LIN Yunfeng, No.24 in South Part of First Ring Road Wuhou Distric, Chengdu Sichuan 4, 610064, CN)
CAI, Xiaoxiao (LIN Yunfeng, No.24 in South Part of First Ring Road Wuhou Distric, Chengdu Sichuan 4, 610064, CN)
MA, Wenjuan (LIN Yunfeng, No.24 in South Part of First Ring Road Wuhou Distric, Chengdu Sichuan 4, 610064, CN)
XIE, Xueping (LIN Yunfeng, No.24 in South Part of First Ring Road Wuhou Distric, Chengdu Sichuan 4, 610064, CN)
Application Number:
CN2018/094562
Publication Date:
May 31, 2019
Filing Date:
July 04, 2018
Export Citation:
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Assignee:
SICHUAN UNIVERSITY (LIN Yunfeng, No.24 in South Part of First Ring Road Wuhou Distric, Chengdu Sichuan 4, 610064, CN)
International Classes:
A61K31/711; A61P25/28
Domestic Patent References:
WO2007122405A12007-11-01
Foreign References:
CN107669697A2018-02-09
CN106497919A2017-03-15
CN106540268A2017-03-29
US20140255307A12014-09-11
Other References:
SHAO, XIAORU ET AL.: "Tetrahedral DNA Nanostructure: A Potential Promoter for Cartilage Tissue Regeneration via Regulating Chondrocyte Phenotype and Proliferation", SMALL, vol. 13, 23 January 2017 (2017-01-23), pages 1 - 12, XP055613706
DONG, SHIBIAO ET AL.: "The DNA Tetrahedron Nanostructure Materials and Their Applications", PROGRESS IN CHEMISTRY, vol. 27, no. 9, 25 August 2015 (2015-08-25), pages 1191 - 1197, XP055502327
Attorney, Agent or Firm:
CHENGDU ZHENGHUA PATENT AGENCY (LI Rui, No.2412 Building 1, Third Period of Longxinjiuxi Square,No.37 In Jiancai Road, Chenghua Distric, Chengdu Sichuan 0, 610000, CN)
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