Title:
USES OF AN ENDOTHELIAL CELL RECEPTOR
Document Type and Number:
WIPO Patent Application WO2003054550
Kind Code:
A8
Abstract:
The subject invention relates to uses of a receptor referred to as GRP78 and to other endothelial cell receptors which bind to the kringle 5 region of mammalian plasminogen. More specifically, identification of the functional properties of this receptor and other such receptors allows for the development and screening of agents which, for example, mimic K5 (i.e, mimetics) and therefore inhibit angiogenesis.
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Inventors:
DAVIDSON DONALD J
Application Number:
PCT/US2002/040966
Publication Date:
August 05, 2004
Filing Date:
December 19, 2002
Export Citation:
Assignee:
ABBOTT LAB (US)
International Classes:
C07K16/18; C07K16/28; G01N33/53; C12N15/09; C12Q1/02; G01N33/15; G01N33/50; G01N33/543; G01N33/566; G01N33/577; A61K38/00; C12R1/91; (IPC1-7): G01N33/566; C07K16/28; A61K38/48
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