Title:
USES OF SPECIFIC ANTIBODY, IMPLANTABLE MEDICAL INSTRUMENT, AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2020/020089
Kind Code:
A1
Abstract:
Provided are the uses of a specific antibody, an implantable medical instrument, and a preparation method therefor. The uses are those of a specific antibody of an ATP-binding cassette transporter in preparing a drug for promoting endothelial repair. The presenthe surface of the implantable medical instrument is loaded with the specific antibody of the ATP-binding cassette transporter. The preparation method comprises loading the specific antibody of the ATP-binding cassette transporter on at least a part of the surface of the implantable medical instrument; and/or binding the specific loaded antibody of the ATP-binding cassette transporter into the hole or the groove of the implantable medical instrument.
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Inventors:
WANG XUAN (CN)
CHEN LU (CN)
LI JUNFEI (CN)
CHEN LU (CN)
LI JUNFEI (CN)
Application Number:
PCT/CN2019/096999
Publication Date:
January 30, 2020
Filing Date:
July 22, 2019
Export Citation:
Assignee:
SHANGHAI MICROPORT MEDICAL GROUP CO LTD (CN)
International Classes:
A61K39/395; A61F2/00; A61F2/06; A61L31/08
Domestic Patent References:
| WO2006014157A1 | 2006-02-09 |
Foreign References:
| CN101172168A | 2008-05-07 | |||
| CN102399741A | 2012-04-04 |
Other References:
"Medical Application of Hemopoietic Stem Cell Gains New Breakthrough", JOURNAL OF FRONTIERS OF MEDICINE, vol. 5, no. 23, 31 August 2015 (2015-08-31)
ZHAO, YACHAO ET AL: "Research Advance of Breast Cancer Resistance Protein", PROGRESS IN MODERN BIOMEDICINE, vol. 10, no. 2, 31 January 2010 (2010-01-31), pages 369 - 371
M. H. G. P. RAAIJMAKERS: "ATP-binding-cassette transporters in hematopoietic stem cells and their utility as therapeutical targets in acute and chronic mye- loid leukemia", LEUKEMIA, vol. 27, no. 10, 1 October 2007 (2007-10-01), pages 2094 - 2102, XP055681648
WU, XUAN ET AL.: "Comparative Study of Different Monoclonal Antibodies for P-glycoprotein in ColonCarcinoma", JOURNAL OF SHANTOU UNIVERSITY MEDICAL COLLEGE, vol. 20, no. 4, 31 December 2007 (2007-12-31), pages 226 - 227
ZHAO, YACHAO ET AL: "Research Advance of Breast Cancer Resistance Protein", PROGRESS IN MODERN BIOMEDICINE, vol. 10, no. 2, 31 January 2010 (2010-01-31), pages 369 - 371
M. H. G. P. RAAIJMAKERS: "ATP-binding-cassette transporters in hematopoietic stem cells and their utility as therapeutical targets in acute and chronic mye- loid leukemia", LEUKEMIA, vol. 27, no. 10, 1 October 2007 (2007-10-01), pages 2094 - 2102, XP055681648
WU, XUAN ET AL.: "Comparative Study of Different Monoclonal Antibodies for P-glycoprotein in ColonCarcinoma", JOURNAL OF SHANTOU UNIVERSITY MEDICAL COLLEGE, vol. 20, no. 4, 31 December 2007 (2007-12-31), pages 226 - 227
Attorney, Agent or Firm:
SHANGHAI SAVVY IP AGENCY CO., LTD. (CN)
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