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Title:
USING ALKYLMETAL REAGENTS FOR DIRECTED METALATION OF AZAAROMATICS
Document Type and Number:
WIPO Patent Application WO2004092125
Kind Code:
A3
Abstract:
Substituted alkylmetal reagents such as (trimethylsilylmethyl)lithium are reacted with azaaromatic compounds and/or nitrogen heterocycle compounds to produce functionalized azaaromatic compounds and functionalized nitrogen heterocycle compounds.

Inventors:
WOLTERMANN CHRISTOPHER J (US)
SUTTON DOUGLAS E (US)
Application Number:
US2004011661W
Publication Date:
April 28, 2005
Filing Date:
April 07, 2004
Export Citation:
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Assignee:
FMC CORPORATION
WOLTERMANN, CHRISTOPHER, J.
SUTTON, DOUGLAS, E.
International Classes:
C07D213/84; C07D217/02; C07D219/00; C07D253/00; C07F1/02; C07D; (IPC1-7): C07D213/84; C07D217/02; C07D219/00; C07D253/00
Foreign References:
US6657093B22003-12-02
Other References:
COMINS D.L.: "Lithiation of methoxypyridines directed by alpha-amino alkoxides", J. ORG. CHEM., vol. 55, no. 1, 1990, pages 69 - 73, XP000983657
See also references of EP 1611102A4
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