Title:
VACCINE COMPOSITION AGAINST MYCOBACTERIAL INFECTION COMPRISING NEW TEMPERATURE SENSITIVE MYCOBACTERIA STRAIN
Document Type and Number:
WIPO Patent Application WO/2016/028028
Kind Code:
A1
Abstract:
Disclosed are an M. paragordonae (strain 49061) strain, which is a temperature sensitive mycobacteria, and a vaccine composition comprising the same. Upon vaccination, the vaccine according to the present invention proliferates in the skin and hypodermis, thereby stimulating immunity, and is inhibited in proliferation due to the characteristic of being able to grow only at temperatures lower than body temperature in the center of the body, and thus the possibility of infection is low. The vaccine of the present invention can be used safely and usefully as a vaccine for prevention of diseases caused by mycobacteria, and for immunotherapy.
Inventors:
KIM BUM JOON (KR)
KIM BYOUNG JUN (KR)
KIM BYOUNG JUN (KR)
Application Number:
PCT/KR2015/008472
Publication Date:
February 25, 2016
Filing Date:
August 13, 2015
Export Citation:
Assignee:
SNU R&DB FOUNDATION (KR)
International Classes:
C12N1/20; A61K35/74; A61P31/04
Foreign References:
| JP2013539014A | 2013-10-17 | |||
| KR20040081423A | 2004-09-21 | |||
| US7867502B1 | 2011-01-11 | |||
| JP2001515870A | 2001-09-25 | |||
| JP2002504106A | 2002-02-05 |
Other References:
KIM, BYOUNG-JUN ET AL.: "Mycobacterium paragordonae sp. nov., a slowly growing, scotochromogenic species closely related to Mycobacterium gordonae", INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, vol. 64, January 2014 (2014-01-01), pages 39 - 45
Attorney, Agent or Firm:
PARK, Weonmee (KR)
박원미 (KR)
박원미 (KR)
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