VACCINE COMPOSITION FOR INDUCING ANTI-IL-23 ANTIBODY

Title:

VACCINE COMPOSITION FOR INDUCING ANTI-IL-23 ANTIBODY

Document Type and Number:

WIPO Patent Application WO/2023/106319

Kind Code:

A1

Abstract:

The present invention provides a vaccine composition which contains a complex of a T-cell receptor antigen peptide and a B-cell receptor antigen peptide and which can induce the production of an antibody against IL-23, wherein the B-cell receptor antigen peptide is represented by formula (I): X1-X2-X3-X4-X5-X6-X7-X8 (in the formula: X1 is S, A, G, T, K or R; X2 is P, A, G, S, T, K or R; X3 is S, A, G, T, K or R; X4 is Q, A, G, T or N; X5 is P, A, G, S, T, Q or N; X6 is W, A, Y or F; X7 is Q, A, G, T or N; and X8 is R, A, G or K).

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Inventors:

NAKAGAMI HIRONORI (JP)
HAYASHI HIROKI (JP)
MORISHITA RYUICHI (JP)
SAKAGUCHI MAKOTO (JP)
KAWABATA SOTARO (JP)

Application Number:

PCT/JP2022/045045

Publication Date:

June 15, 2023

Filing Date:

December 07, 2022

Export Citation:

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Assignee:

UNIV OSAKA (JP)
FUNPEP CO LTD (JP)

International Classes:

A61K39/00; A61K47/55; A61P1/04; A61P3/10; A61P9/00; A61P9/10; A61P17/00; A61P17/06; A61P19/00; A61P19/02; A61P25/00; A61P25/28; A61P27/02; A61P29/00; A61P35/00; A61P37/00; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07K7/06; C07K7/08; C07K14/00; C07K14/54

Domestic Patent References:

WO2017164409A1

2017-09-28

Foreign References:

JP2010518858A

2010-06-03

Other References:

HIROSHI KATAYAMA: "Development of psoriasis by continuous neutrophil infiltration into the epidermis", EXPERIMENTAL DERMATOLOGY, BLACKWELL MUNSGAARD, COPENHAGEN; DK, vol. 27, no. 10, 14 August 2018 (2018-08-14), COPENHAGEN; DK , pages 1084 - 1091, XP071778688, ISSN: 0906-6705, DOI: 10.1111/exd.13746
TENMA AKIKO, NAKAGAMI HIRONORI, TOMIOKA HIDEKI, SAKAGUCHI MAKOTO, IDE RYOKO, KORIYAMA HIROSHI, HAYASHI HIROKI, SHIMAMURA MUNEHISA,: "AJP001, a novel helper T‐cell epitope, induces a humoral immune response with activation of innate immunity when included in a peptide vaccine", FASEB BIOADVANCES, vol. 1, no. 12, 1 December 2019 (2019-12-01), pages 760 - 772, XP093070488, ISSN: 2573-9832, DOI: 10.1096/fba.2019-00056
ANONYMOUS: " Fiscal Year Ending December 2020 Financial Results", FUNPEP CO., LTD. STOCK CODE: 4881, 18 February 2021 (2021-02-18), XP093070489, Retrieved from the Internet [retrieved on 20230804]

Attorney, Agent or Firm:

KAMADA, Mitsunori et al. (JP)

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