Title:
VACCINE CONTAINING IMMOBILIZED VIRUS PARTICLES
Document Type and Number:
WIPO Patent Application WO/2017/122635
Kind Code:
A1
Abstract:
The present invention relates to a vaccine containing immobilized virus particles, wherein the sum total of exothermic reactions in three rabbits in an exothermic test on the immobilized virus particles is less than 80% relative to the sum total of exothermic reactions in three rabbits in the exothermic test on virus particles from which the immobilized virus particles are originated or inactivated virus particles which correspond to the immobilized virus particles.
Inventors:
ONUMA HIROTO (JP)
TSURUDOME YUKARI (JP)
IKEDA KAZUYUKI (JP)
YAMAUE RYO (JP)
KIMACHI KAZUHIKO (JP)
ABE MOTOHARU (JP)
WATANABE AKIHIRO (JP)
OHARA YUKI (JP)
TSURUDOME YUKARI (JP)
IKEDA KAZUYUKI (JP)
YAMAUE RYO (JP)
KIMACHI KAZUHIKO (JP)
ABE MOTOHARU (JP)
WATANABE AKIHIRO (JP)
OHARA YUKI (JP)
Application Number:
PCT/JP2017/000485
Publication Date:
July 20, 2017
Filing Date:
January 10, 2017
Export Citation:
Assignee:
THE CHEMO-SERO-THERAPEUTIC RES INST (JP)
International Classes:
A61K39/12; A61K31/12; A61K31/16; A61K39/145; A61P1/16; A61P31/14
Domestic Patent References:
| WO2001076624A1 | 2001-10-18 |
Foreign References:
| JP2003517834A | 2003-06-03 | |||
| CN104498446A | 2015-04-08 | |||
| JP2002528422A | 2002-09-03 | |||
| JP2010514817A | 2010-05-06 |
Other References:
DELRUE, I. ET AL.: "Inactivated virus vaccines from chemistry to prophylaxis: Merits, risks and challenges", EXPERT REVIEW OF VACCINES, vol. 11, no. 6, 2012, pages 695 - 719, XP055399927
See also references of EP 3403671A4
See also references of EP 3403671A4
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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