VACCINE AND METHOD FOR TREATMENT OF MOTOR NEURONE DISEASES

Title:

VACCINE AND METHOD FOR TREATMENT OF MOTOR NEURONE DISEASES

Document Type and Number:

WIPO Patent Application WO2003047500

Kind Code:

A3

Abstract:

A vaccine for reducing disease progression, and/or protection of motor nerve degeneration, and/or protection from glutamate toxicity in motor neurone disease (MND), particularly amyotrophic lateral sclerosis (ALS), patients, comprising an active agent selected from the group consisting of Cop 1, a Cop 1-related peptide, a Cop 1-related polypeptide, and poly-Glu,Tyr. The active agent is preferably Cop 1 or poly-Glu,Tyr, and can be administered with or without an adjuvant.

More Like This:

WO/2003/099332	MEDICINAL COMPOSITION FOR INHIBITING THE EXPRESSION OF ATP-CITRATE LYASE AND USE THEREOF
JPS6056143	[Title of the Invention] A friend gin derivative and its manufacturing process
WO/1997/043239	INHIBITION OF MATRIX METALLOPROTEASES BY SUBSTITUTED BIARYL OXOBUTYRIC ACIDS

Inventors:

EISENBACH-SCHWARTZ MICHAL (IL)
YOLES ESTHER (IL)

Application Number:

PCT/IL2002/000979

Publication Date:

March 18, 2004

Filing Date:

December 05, 2002

Export Citation:

Click for automatic bibliography generation Help

Assignee:

YEDA RES & DEV (IL)
EISENBACH-SCHWARTZ MICHAL (IL)
YOLES ESTHER (IL)

International Classes:

A61K31/426; A61K38/16; A61K39/00; A61K39/39; A61P21/00; A61P25/00; A61P25/28; A61P27/06; A61K; (IPC1-7): A61K38/16; C07K14/00

Foreign References:

US5800808A	1998-09-01
US3849550A	1974-11-19

Other References:

KIPNIS ET AL.: "Vaccination with a safe MBP-crossreactive peptide as a possible treatment for CNS injuries", . NEUROTRAUMA, vol. 17, no. 10, 2000, pages 991, XP002964070

Download PDF:

View/Download PDF PDF Help

Previous Patent: AMPHIPHILIC COMPOUNDS AND VESICLES/LIPOSOMES FOR ORGAN-SPECIFIC DRUG TARGETING

Next Patent: NOVEL ANTI-CANCER THERAPEUTIC COMPOUNDS