Title:
VALVES AND PUMPS FOR MICROFLUIDIC SYSTEMS AND METHOD FOR MAKING MICROFLUIDIC SYSTEMS
Document Type and Number:
WIPO Patent Application WO2002053290
Kind Code:
A3
Abstract:
The present invention relates to microfluidic systems, including valves (12) and pumps for microfluidic systems. The valves of the invention include check valves (30) such as diaphragm valves and flap valves. Other valves of the invention include one-use valves (12). The pumps of the present invention include a reservoir (40) and at least two check valves (30, 31). The reservoir (40) may be a variable volume. The present invention also relates to a flexible microfluidic system (10). The present invention additionally relates to a method of making microfluidic systems (10) including those of the present invention. The method includes forming a microfluidic system on a master (100), connecting a support (110) to the microfluidic system (10) and removing the microfluidic system (10) from the master (100). The support (110) may remain connected to the microfluidic system (10) or the microfluidic system (10) may be transferred to another substrate. The present invention further relates to a method of manipulating a flow of a fluid in a microfluidic system. This method includes initiating fluid flow in a first direction (50) and inhibiting fluid flow in a second direction (50) and may be practiced with the valves (12) of the present invention.
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Inventors:
JEON NOO LI
CHIU DANIEL T
WARGO CHRISTOPHER J
CHOI INSUNG S
WU HONGKAI
ANDERSON JANELLE R
WHITESIDES GEORGE M
MCDONALD J COOPER
METALLO STEVEN J
STONE HOWARD A
CHIU DANIEL T
WARGO CHRISTOPHER J
CHOI INSUNG S
WU HONGKAI
ANDERSON JANELLE R
WHITESIDES GEORGE M
MCDONALD J COOPER
METALLO STEVEN J
STONE HOWARD A
Application Number:
PCT/US2002/000293
Publication Date:
February 20, 2003
Filing Date:
January 08, 2002
Export Citation:
Assignee:
HARVARD COLLEGE (US)
International Classes:
B01L3/00; B81B3/00; B81B1/00; B81C99/00; F04B43/04; F04D29/00; F04D33/00; F15C5/00; F16K15/16; F16K99/00; (IPC1-7): F04B39/10
Domestic Patent References:
| WO2000062931A1 | 2000-10-26 |
Foreign References:
| US6136212A | 2000-10-24 | |||
| US5863801A | 1999-01-26 | |||
| US5976336A | 1999-11-02 | |||
| US6210986B1 | 2001-04-03 | |||
| US6306273B1 | 2001-10-23 | |||
| US6227824B1 | 2001-05-08 | |||
| US6261066B1 | 2001-07-17 | |||
| US5962081A | 1999-10-05 |
Other References:
See also references of EP 1350029A4
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