Title:
VANCOMYCIN SULFONIUM DERIVATIVE AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USES
Document Type and Number:
WIPO Patent Application WO/2020/057422
Kind Code:
A1
Abstract:
A vancomycin derivative represented by general formula (I) and a pharmaceutically acceptable salt thereof, a preparation method for the vancomycin derivative, and uses of these compounds in preparation of medicaments for treating and/or preventing bacterial infectious diseases, in particular for treating infectious diseases caused by Gram-positive bacteria.
Inventors:
HUANG WEI (CN)
LAN LEFU (CN)
GUAN DONGLIANG (CN)
CHEN FEIFEI (CN)
TANG FENG (CN)
JIANG BOFENG (CN)
ZHOU MANG (CN)
LAN LEFU (CN)
GUAN DONGLIANG (CN)
CHEN FEIFEI (CN)
TANG FENG (CN)
JIANG BOFENG (CN)
ZHOU MANG (CN)
Application Number:
PCT/CN2019/105489
Publication Date:
March 26, 2020
Filing Date:
September 12, 2019
Export Citation:
Assignee:
SHANGHAI INST MATERIA MEDICA CAS (CN)
International Classes:
A61K38/14; A61P31/00; C07K9/00
Foreign References:
| CN108409837A | 2018-08-17 | |||
| CN101222933A | 2008-07-16 |
Other References:
GUAN, DONGLIANG ET AL.: "Sulfonium, an Underestimated Moiety for Structural Modification, Alters the Antibacterial Profile of Vancomycin Against Multi- drug-Resistant Bacteria", ANGEWANDTE CHEMIE (INTERNATIONAL ED. IN ENGLISH, vol. 130, 13 May 2019 (2019-05-13), pages 6678 - 6682, XP055696008, DOI: 10.1002/ange.201902210
Attorney, Agent or Firm:
KINGSOUND & PARTNERS (CN)
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