Title:
VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS
Document Type and Number:
WIPO Patent Application WO2004014871
Kind Code:
A8
Abstract:
Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
Inventors:
CHKRABARTI PARTHA P (IN)
CHEN NING (US)
DOHERTY ELIZABETH M (US)
DOMINGUEZ CELIA (US)
FALSEY JAMES RICHARD (US)
FOTSH CHRISTOPHER H (US)
HULME CHRISTOPHER (US)
KATON JODIE (US)
NIXEY THOMAS (US)
NORMAN MARK H (US)
OGNYANOV VASSIL I (US)
PETTUS LIPING H (US)
RZASA ROBERT MICHAEL (US)
STEC MARKIAN (US)
WANG HUI-LING (US)
ZHU JIAWANG (US)
CHEN NING (US)
DOHERTY ELIZABETH M (US)
DOMINGUEZ CELIA (US)
FALSEY JAMES RICHARD (US)
FOTSH CHRISTOPHER H (US)
HULME CHRISTOPHER (US)
KATON JODIE (US)
NIXEY THOMAS (US)
NORMAN MARK H (US)
OGNYANOV VASSIL I (US)
PETTUS LIPING H (US)
RZASA ROBERT MICHAEL (US)
STEC MARKIAN (US)
WANG HUI-LING (US)
ZHU JIAWANG (US)
Application Number:
PCT/US2003/025191
Publication Date:
April 07, 2005
Filing Date:
August 08, 2003
Export Citation:
Assignee:
AMGEN INC (US)
CHAKRABARTI PARTHA P (US)
CHEN NING (US)
DOHERTY ELIZABETH M (US)
DOMINGUEZ CELIA (US)
FALSEY JAMES RICHARD (US)
FOTSH CHRISTOPHER H (US)
HULME CHRISTOPHER (US)
KATON JODIE (US)
NIXEY THOMAS (US)
NORMAN MARK H (US)
OGNYANOV VASSIL I (US)
PETTUS LIPING H (US)
RZASA ROBERT MICHAEL (US)
STEC MARKIAN (US)
WANG HUI-LING (US)
ZHU JIAWANG (US)
CHAKRABARTI PARTHA P (US)
CHEN NING (US)
DOHERTY ELIZABETH M (US)
DOMINGUEZ CELIA (US)
FALSEY JAMES RICHARD (US)
FOTSH CHRISTOPHER H (US)
HULME CHRISTOPHER (US)
KATON JODIE (US)
NIXEY THOMAS (US)
NORMAN MARK H (US)
OGNYANOV VASSIL I (US)
PETTUS LIPING H (US)
RZASA ROBERT MICHAEL (US)
STEC MARKIAN (US)
WANG HUI-LING (US)
ZHU JIAWANG (US)
International Classes:
A61P29/00; C07D209/08; C07D209/12; C07D209/42; C07D209/48; C07D213/26; C07D213/643; C07D213/74; C07D213/75; C07D215/227; C07D215/38; C07D217/04; C07D231/40; C07D231/56; C07D233/38; C07D239/42; C07D239/90; C07D241/42; C07D263/56; C07D265/36; C07D277/62; C07D277/82; C07D307/79; C07D319/20; C07D401/12; C07D403/12; C07D405/12; C07D407/12; C07D409/14; C07D413/12; C07D417/12; C07D213/64; C07D215/22; (IPC1-7): C07D239/34; C07D239/38; C07D417/12; C07D401/14; C07D401/12; C07D403/12; C07D405/12; C07D409/12; C07D413/12; C07D413/14; C07D405/14; C07D417/14; C07D471/04; A61K31/501; A61K31/506; A61K31/505; A61K31/4427; A61K31/5377; A61K31/551; A61P29/00
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