VAPORIZATION DEVICE

FIELD OF THE INVENTION

[001] The present invention relates to the field of vaporization devices. Specifically, the present invention relates to a vaporization device having a fluid control mechanism which enables to provide specific doses of various types of chemicals or liquids for evaporation and inhalation, and optionally provide customized blends thereof, such as for example of different types of cannabinoids.

BACKGROUND OF THE INVENTION

[002] Standard vaporization devices have common components including a heating element, a vaporization or mixing chamber, a power source, a mouthpiece, and a liquid reservoir or tank. The liquid reservoir is typically filled with a liquid (sometimes termed "electronic liquid" or "e-liquid") which may include essential oils and/or various chemicals such as nicotine, tobacco and/or Cannabis-based compositions (typically containing a single strain of cannabinoid or several strains). A wicking element transfers portions of the liquid from the reservoir to the vaporization chamber. The heating element is typically connected to the wicking element and/or to the reservoir to enable the heating thereof, to produce vapors.

[003] In order to activate a typical vaporization device, a user (e.g., a human) inhales directly through the mouthpiece of the device. When sensors inside the device sense the inhalation via a change in pressure or otherwise, they activate the heating element which heats up the liquid in the reservoir. The heating element is required to provide an appropriate amount of heat for a particular type or types of liquid(s), wherein low heat cannot reach the desired point of boiling or vaporization thereof, and excessive heat could potentially produce toxins or burn desired potential chemicals, such as different strains/types of cannabinoids having different boiling or vaporization temperatures.

[004] Today, different types of vaporization devices for liquids containing one or more materials such as nicotine, tobacco, and cannabis are known. For example, US Pat. No. 8,897,628 discloses an electronic vaporizer having a cartridge that facilitates provision of a vaporized solution to an individual, wherein the cartridge includes a housing that includes an interior, wherein the housing is one of a polymer housing or a ceramic housing. The cartridge also includes a heating element located in the interior of the housing, wherein the heating element is configured to vaporize a solution for oral provision to the individual.

[005] US Pat. No. 8,794,231 discloses an electrically heated smoking system including a shell and a replaceable mouthpiece, wherein the shell includes an electric power supply and electric circuitry. The mouthpiece includes a liquid storage portion and a capillary wick having a first end and a second end. The first end of the wick extends into the liquid storage portion for contact with liquid therein. The mouthpiece also includes a heating element for heating the second end of the capillary wick, an air outlet, and an aerosol forming chamber between the second end of the capillary wick and the air outlet.

[006] US Pat. No. 10,034,495 discloses an electronic smoking device, having an outer tube mounted around at least a portion of an inner tube. The outer tube can have an outer surface and an inner surface. The inner tube can have an inner surface defining an air path and an outer surface. An annular liquid storage tank is defined between the outer surface of the inner tube and the inner surface of the outer tube. A heater enclosure can define a heater coil chamber. A heater coil can be mounted at least partially within the heater enclosure. A wick can include a first end portion. The wick can extend through a center of the heater coil and the first end portion can extend into a first wick bore in a first wall of the heater enclosure.

[007] US Pat. No. 10,925,319 discloses a vaporization device having a plurality of pens each having a battery, a mouthpiece, a ventilated end, a vaporization chamber containing a coil, a battery, a PCB, a sensor, and a tank containing e-liquid, in order to create a mixed vaporization product in a single vaporization event.

[008] US App. No. 20200022416 discloses a vaporizing article, comprises a vaporizer drive circuit; one or more memories configured to store a percentage of at least one constituent in an inhalation media, one or more compensation values for at least one compensation category for the at least one constituent, and instructions; and a control circuit comprising a processor coupled with the one or more memories configured to run the instructions, the instructions configured to cause the processor to: receive a dose target for a constituent; determine whether to perform compensation for an inhalation media dose in order to ensure the dose target is met; when compensation is to be performed, determine the properly compensated inhalation media dose based on an associated compensation value for the constituent; and control the vaporizer drive circuit so as to dispense a compensated dose of the inhalation media.

[009] In recent years, the use of medical cannabis (termed ‘MC’) for the treatment of chronic pain has emerged, along with an increase in demand and use by migraine patients. The cannabis plant contains hundreds of different active components including phytocannabinoids, terpenes and flavonoids. While Tetrahydrocannabinol (THC) and cannabidiol (CBD) are among the most well-known phytocannabinoids, others are likely to have biological activity as well. It is known that single cannabinoids have been shown to exert biological activity, Cannabis synergy, also known as the “entourage effect”, in which the combination of a variety of “minor cannabinoids” and Cannabis terpenoids markedly increase the activity of the primary endogenous cannabinoids. The multi-compound entourage effect suggests that studies examining the role of single-molecule cannabinoids in disease may not necessarily capture the synergies in multi-compound MC treatment. To add to the complexity of MC treatment with multiple compounds, there are hundreds of different cannabis chemovars, each having its own unique chemical composition. Thus, Cannabis-bas d compositions and/or mixtures containing combinations of different cannabinoids can be used in a variety of pharmaceutical applications in order to obtain high medical efficacy, relative to the use of a single strain of cannabinoid, for example as disclosed in detail at International Pub. No. WO 2020161715.

[010] In order to create a personalized blend or mixture of liquid flavor(s) and ingredients, such as for example different types or doses of cannabinoids having various therapeutic effects, it is required to heat different ingredients separately to different boiling/vaping temperatures, which may not overlap. In a typical vaporization device the heating element heats up the liquid in the reservoir or at a close proximity thereto. A possible drawback of the existing devices may result in the overheating of the liquid due to its different inner boiling points, which can result in the burning thereof such that the beneficial effects of the liquid are not obtained, and the burned chemicals can be toxic, harmful and have an unpleasant taste. Moreover, the existing devices cannot enable to create a personalized blend or mixture of liquid flavor(s) and ingredients, such as including different types or doses of cannabinoids. Furthermore, it can be challenging to mix different types of liquids for vaporization in a single chamber, since they can have different properties (e.g., viscosities), and therefore not easily form a homogeneous mixture. Thus, a single reservoir chamber cannot contain different chemicals, each having different properties and therapeutic effects.

[Oil] Thus, there is an ongoing need to provide a vaporization device which can produce specific doses of various types of chemicals or liquids for evaporation and inhalation, and optionally provide customized blends of liquid flavors and vapors, while preventing producing toxins or burning liquid ingredients.

SUMMARY OF THE INVENTION

[012] The present disclosure is directed toward a vaporization device having a novel fluid control mechanism which enables to provide specific doses of various types of liquid compositions for inhalation, and optionally provide customized blends or mixtures of liquid compositions flavors and vapors consisting of different types of materials (e.g., cannabinoids).

[013] Thus, according to a certain aspect, there is provided a vaporization device comprising: a liquid cartridge chamber configured to accommodate a liquid cartridge comprising a plurality of liquid chambers therein, wherein each liquid chamber is configured to contain a liquid composition therein; a mixing chamber; a fluid control mechanism comprising a plurality of transferring elements and a plurality of flow inducing elements, wherein a first end or surface of each transferring element is in fluid communication with a corresponding liquid chamber, wherein a second end or surface of each transferring element is in fluid communication with the mixing chamber, and wherein at least a portion of each transferring element is directly or indirectly coupled to at least one corresponding flow inducing element; a mouthpiece comprising at least one fluid path extending from a ventilation end of the mouthpiece and the mixing chamber, wherein said at least one fluid path is configured to enable fluid communication therethrough; a controller configured to control production of energy by each flow inducing element applied to a corresponding transferring element, wherein the amount of energy is configured to facilitate flow of a predetermined dose of liquid drawn from each liquid chamber or to transform said liquid into vapor, and a power source chamber configured to accommodate a power source therein for providing power at least to the controller and the plurality of flow inducing elements.

[014] Advantageously, according to some embodiments, the vaporization device of the present invention comprises a plurality (i.e., two or more) of liquid chambers, wherein each chamber comprises a c comprising one or more strand(s) of cannabinoid(s), optionally having different properties (e.g., various boiling points, viscosities, types, etc.), in order to enable to form customized blends thereof for a single combined inhalation by a user, while preventing producing toxins or burning liquid ingredients, unlike typical vaporization devices having a single reservoir chamber which cannot contain different liquid compositions and therefore cannot enable to form customized blends having various therapeutic effects.

[015] According to another aspect, there is provided a method for providing customized mixtures of aerosols for inhalation by a user, the method comprising: (a) providing the vaporization device as disclosed herein; (b) selecting a liquid mixture formula via the user interaction portion; (c) actuating the fluid control mechanism, thereby producing energy by each flow inducing element and applying it to a corresponding transferring element, according to the predetermined liquid mixture formula of step (b); and (d) forming a vapor mixture within the mixing chamber, wherein said vapor condenses to form an inhalable aerosol mixture therein.

[016] According to another aspect, there is provided a method for treating or suppressing a disease or a disorder selected from the group consisting of cancer, chronic pain, migraine, and a combination thereof, wherein the method comprises providing customized mixtures of aerosols for inhalation by a user in need thereof according to the method as disclosed herein. [017] According to another aspect, there is provided a liquid cartridge configured to be detachably attached to a vaporization device, the liquid cartridge comprising: a cartridge housing accommodating therein a plurality of liquid chambers, wherein each liquid chamber comprises: a liquid chamber outlet configured to be fluidly coupled to a mixing chamber, a liquid chamber housing coupled to the cartridge housing, wherein said liquid chamber housing is defining an inner surface, at least one transferring element coupled to at least one corresponding flow inducing element, wherein the transferring element and corresponding flow inducing element are disposed within the liquid chamber, such that the liquid chamber defines a chamber inner space between the inner surface and the transferring element, wherein the chamber inner space is configured to contain a liquid composition disposed therein, wherein the chamber inner space is in fluid communication with the transferring element, and wherein the transferring element is configured to allow liquid flow from the chamber inner space therethrough and toward the liquid chamber outlet, a mixing chamber, wherein the mixing chamber is fluidly coupled to each liquid chamber, and wherein the mixing chamber comprises a mixing chamber exit configured to enable fluid flow therefrom and into a portion of the vaporization device when attached thereto; and wherein the cartridge housing comprises a plurality of fluid intake apertures configured to facilitate fluid communication between an external environment of the device and each liquid chamber and/or the mixing chamber.

[018] Certain embodiments of the present invention may include some, all, or none of the above advantages. Further advantages may be readily apparent to those skilled in the art from the figures, descriptions, and claims included herein. Aspects and embodiments of the invention are further described in the specification herein below and in the appended claims. [019] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In case of conflict, the patent specification, including definitions, governs. As used herein, the indefinite articles "a" and "an" mean "at least one" or "one or more" unless the context clearly dictates otherwise.

[020] The following embodiments and aspects thereof are described and illustrated in conjunction with systems, tools and methods which are meant to be exemplary and illustrative, but not limiting in scope. In various embodiments, one or more of the above-described problems have been reduced or eliminated, while other embodiments are directed to other advantages or improvements.

BRIEF DESCRIPTION OF THE FIGURES

[021] Some embodiments of the invention are described herein with reference to the accompanying figures. The description, together with the figures, makes apparent to a person having ordinary skill in the art how some embodiments may be practiced. The figures are for the purpose of illustrative description and no attempt is made to show structural details of an embodiment in more detail than is necessary for a fundamental understanding of the invention. For the sake of clarity, some objects depicted in the figures are not to scale.

[022] In the Figures:

[023] Figure 1 illustrates a cross sectional side view of a vaporization device 100, according to some embodiments.

[024] Figures 2 and 3 illustrates cross sectional views of portions of the liquid cartridge 110 and fluid control mechanism 160, according to different embodiments.

[025] Figure 4 illustrates a cross sectional view of a portion of the liquid cartridge 110 and a portion of a fluid control mechanism 260, according to some embodiments.

[026] Figure 5A illustrates a bottom view of a portion of the liquid cartridge 110 and a portion of the fluid control mechanism 260 of Figure 4, according to some embodiments. [027] Figure 5B illustrates a cross sectional view in perspective of a portion of the liquid cartridge 110 and the fluid control mechanism 260 taken from line 5B-5B of Figure 5A, according to some embodiments.

[028] Figure 5C illustrates a bottom view of a portion of the liquid cartridge 110 and a portion of the fluid control mechanism 260, according to some embodiments.

[029] Figures 6A-B illustrates a cross sectional view and a cross sectional view in perspective, respectively, of a portion of the liquid cartridge 110 and a portion of a fluid control mechanism 360, according to different embodiments.

[030] Figures 7A-B illustrates a cross sectional view and a cross sectional view in perspective, respectively, of a portion of the liquid cartridge 110 and a portion of a fluid control mechanism 460, according to some embodiments.

[031] Figures 8A-B illustrates a cross sectional view and a cross sectional view in perspective, respectively, of a portion of the liquid cartridge 110 and a portion of a fluid control mechanism 560, according to some embodiments.

[032] Figures 9A-B illustrates different views in perspective of a liquid cartridge 610 and a portion thereof, respectively, according to some embodiments.

[033] Figures 9C-D illustrates cross sections of a liquid chamber 612, according to some embodiments.

[034] Figure 10 illustrates a cross sectional side view of a vaporization device 600 comprising the fluid control mechanism 660, according to some embodiments.

[035] Figures 11A-B illustrates cross sectional views of a liquid chamber 712 and a device 600 comprising a fluid control mechanism 760, respectively, according to some embodiments.

[036] Figure 12 illustrates a cross sectional side view of a liquid chamber 712 comprising a fluid control mechanism 860, according to some embodiments. [037] Figure 13 illustrates a cross sectional side view of a liquid chamber 712 comprising a fluid control mechanism 960, and an enlargement of a portion thereof, according to some embodiments.

[038] Figure 14 illustrates a method 1000 for providing customized mixtures of aerosols for inhalation, according to some embodiments

DETAILED DESCRIPTION OF SOME EMBODIMENTS

[039] The present disclosure is directed toward a vaporization device having a novel fluid control mechanism which enables to provide specific and/or customized doses of various types of liquid compositions for inhalation, and optionally provide customized blends or mixtures of liquid compositions flavors and vapors consisting of different types of materials having various different properties (e.g., viscosities, boiling points, etc.), while preventing producing toxins or burning liquid composition ingredients. Specifically, said liquid compositions may contain different strands of cannabinoids, wherein the inhalation of the vapors thereof can result in various therapeutic effects.

[040] In the following description, various aspects of the disclosure will be described. For the purpose of explanation, specific configurations and details are set forth in order to provide a thorough understanding of the different aspects of the disclosure. However, it will also be apparent to one skilled in the art that the disclosure may be practiced without specific details being presented herein. Furthermore, well-known features may be omitted or simplified in order not to obscure the disclosure.

[041] Throughout the figures of the drawings, different superscripts for the same reference numerals are used to denote different embodiments of the same elements. Embodiments of the disclosed devices and systems may include any combination of different embodiments of the same elements. Specifically, any reference to an element without a superscript may refer to any alternative embodiment of the same element denoted with a superscript. In order to avoid undue clutter from having too many reference numbers and lead lines on a particular drawing, some components will be introduced via one or more drawings and not explicitly identified in every subsequent drawing that contains that component.

[042] As was disclosed herein above, it can be beneficial to provide a liquid composition or a liquid mixture for vaporization and subsequent inhalation in a vaporization device, wherein the liquid composition or mixture comprises customized doses of organic compounds including a plurality of various types of cannabinoids which are present in the composition in relative amounts that are substantially identical to their relative amounts in the Cannabis extract, and thus can provide a variety of therapeutic beneficial effects.

[043] Furthermore, as was disclosed above, it can be challenging to mix different types of liquid compositions for vaporization and subsequent inhalation in a single reservoir chamber of a vaporization device, since different types of liquids can have different properties (e.g., viscosities), and therefore not easily form a homogeneous mixture. Moreover, different ingredients of liquid compositions or mixtures, such as essential oils, nicotine, tobacco, and various strains of cannabinoids or other Cannabis extracts, each have different boiling or vaporization temperatures.

[044] For example, Tetrahydrocannabinol (THC) is a principal psychoactive type of cannabinoid, which has various therapeutic effects and may assist in alleviating symptoms of pain and other physical discomfort. THC is often vaped at a temperature of about 155-160 °C. Cannabidiol (CBD) is another type of cannabinoid, which is non-psychoactive and has various therapeutic effects, including anti-convulsant (suppresses epileptic seizures), anti-cancer (hampers the growth of tumor cells), anti-inflammatory and anti-oxidant properties (fights against neurodegenerative disorders such as Alzheimer's disease). Studies also show that CBD alleviates anxiety and depression. CBD is often vaped at a temperature of about 160-180 °C. Cannabidol (CBN) is a byproduct which is formed during THC degradation. CBN has various therapeutic effects and was found useful in inducing sleep, thus making it a good drug for users suffering from insomnia. CBN is often vaped at a temperature of about 185 °C.

[045] Liquid compositions for vaporization and subsequent inhalation can also include various types of essential oils, which consists of different components such as terpenoid hydrocarbons, oxygenated terpenes and sesquiterpenes, which are responsible for the characteristic aroma/smell of the induced vapors. Different types of essential oils vary in their boiling points and each contain a variety of different terpenes (which are the fragrance molecules).

[046] Therefore, it is problematic to heat and vaporize liquid compositions or mixtures as disclosed above in a single chamber at a specific temperature, which may result in the burning thereof, such that the beneficial effects of the liquids are not obtained, and the burned ingredients can be toxic, harmful and have an unpleasant taste. Furthermore, a single chamber does not enable to form customized doses of different cannabinoids mixtures.

[047] Accordingly, in some embodiments, in order to maintain the synergy between different Cannabis constituents, known as the entourage effect, the present invention provides a vaporization device comprising a plurality (i.e., two or more) of liquid chambers, wherein each chamber comprises a liquid composition comprising one or more strand(s) of different cannabinoid(s) having different properties (e.g., various boiling points and viscosities), in order to enable to form customized blends thereof for a single combined inhalation by a user, while preventing producing toxins or burning liquid ingredients.

[048] Thus, according to an aspect of the present invention, there is provided a vaporization device comprising a plurality of liquid chambers and a fluid control mechanism configured to deliver or draw or wick a predetermined volume (e.g., a dose) of a liquid composition from each one of the plurality of liquid chambers via a corresponding plurality of transferring elements, respectively. Each transferring element is directly or indirectly connected to a flow inducing element configured to provide a specific amount of energy (e.g., thermal, vibration, etc.) to the wicked dose disposed therein, and thus to enable the liquid to be easy flow therethrough (and optionally be preheated) or to be transferred into vapors, according to the liquid's properties or the device's mode of operation. According to some embodiments, the fluid control mechanism can enable to deliver or transfer or wick customized liquid volumes (e.g., doses) from a plurality of liquid chambers, each preferably containing a different liquid composition, such that each liquid composition has different properties and ingredients (e.g., various cannabinoids mixtures). In some embodiments, the fluid control mechanism is configured to provide direct energy to each transferring element, preferably without affecting the liquid chambers, which may affect or harm the materials disposed therein. For example, in some embodiments, the fluid control mechanism is configured to provide direct heat to each transferring element, preferably without transferring heat to the liquid chamber.

[049] According to some embodiments, the fluid control mechanism enables to directly heat the delivered or wicked dose disposed within or transferring or flowing through each transferring element, such that the viscosity and/or capillary forces within the liquid are reduced, which enable the dose to flow easily into a mixing chamber in liquid form. The mixing chamber may contain an additional heating element, configured to enable the evaporation of the liquids disposed therewithin and the formation of aerosols, for subsequent inhalation by a user. Thus, the fluid control mechanism can enable to heat different liquid doses residing within different transferring elements to different customized temperatures, such that each liquid dose will easily flow into the mixing chamber. Advantageously, in some embodiments, this configuration can be beneficial to maintain the entourage effect, in cases where each one of the plurality of liquid chambers contains a different liquid composition comprising one or more type(s) of cannabinoids having different properties (e.g., viscosities, boiling points, etc.), and therefore the liquid within each chamber flows in a different range of temperatures and cannot be contained and mixed beforehand in a single liquid chamber. Furthermore, by providing a plurality of liquid chambers, wherein each chamber comprises a different liquid composition comprising one or more types or strands of cannabinoids, the fluid control mechanism enables to provide customized mixtures of the cannabinoids from each liquid chamber, and thus to maintain the entourage effect and to provide a variety of therapeutic beneficial effects upon user demand.

[050] According to some alternative embodiments, the fluid control mechanism enables to directly heat the wicked dose disposed within each transferring element, such that the liquid composition evaporates into the mixing chamber. Thus, the fluid control mechanism can enable to heat different liquid doses residing within different transferring elements to different customized temperatures, such that each liquid dose will easily evaporates into the mixing chamber, while preventing producing toxins or burning liquid ingredients. Advantageously, in some embodiments, this configuration can be beneficial to maintain the entourage effect in cases where each one of the plurality of liquid chambers contains a liquid composition having a cannabinoids mixture with a different boiling point, relative to the mixture disposed within a different chamber. Thus, the fluid control mechanism of the present invention enables to provide customized doses of liquid flavors and vapors, optionally consisting of different types of chemicals or liquids having various boiling points (e.g., different types of cannabinoids), while preventing producing toxins or burning liquid ingredients, in order to provide customized mixtures of the cannabinoids from each liquid chamber, and thus to maintain the entourage effect and to provide a variety of therapeutic beneficial effects upon user demand.

[051] Reference is now made to Figures 1-3. Figure 1 illustrates a cross sectional side view of a vaporization device 100, according to some embodiments. Figures 2 and 3 illustrates cross sectional views of portions of a liquid cartridge 110 and a fluid control mechanism 160, according to different embodiments.

[052] According to some embodiments, there is provided a vaporization device 100 comprising a housing 104 comprising: a liquid cartridge chamber 116 optionally comprising a liquid cartridge 110 comprising one or more liquid chamber(s) 112 disposed therein, a mixing chamber 120, a power source chamber 138 optionally comprising a power source 130 disposed therein, a mouthpiece 140, a controller 150, and a fluid control mechanism.

[053] According to some embodiments, the liquid cartridge 110 is disposed within the liquid cartridge chamber 116 (see Figure 1), and is optionally configured to be detachably attached therefrom. According to some embodiments, the liquid cartridge 110 is disposed within the mouthpiece 140. According to some embodiments, the liquid cartridge 110 is detachably attached from the mouthpiece 140, the housing 104, or both.

[054] According to some embodiments, the liquid cartridge 110 is detachably attached from the housing 104, or specifically from the liquid cartridge chamber 116, via various attachment means, such as at least one locking mechanism 117 (see Figure 1). In further embodiments, said locking mechanism 117 comprises a movable protrusion 118 and a corresponding recess 119 disposed within the liquid cartridge chamber 116 configured to receive the protrusion 118. The protrusion 118 can transition between a 'locked state' in which it is disposed within the recess 119, thereby locking the cartridge 110 in the liquid cartridge chamber 116; and a 'free state' in which the protrusion 118 is disposed within a portion of the housing 104 and/or the mouthpiece 140, thereby enabling the cartridge 110 to be detached from the liquid cartridge chamber 116. The protrusion 118 can transition between the locked state to the free state via the application of an external force by the user, enabling to move or slide the protrusion 118 between the two states.

[055] According to some embodiments, the liquid cartridge 110 comprises a plurality of liquid chambers 112. In further embodiments, the liquid chambers 112 are spaced one from the other within the cartridge 110. In some embodiments, the liquid chambers 112 are at least partially encased or enveloped by the cartridge 110. In some embodiments, each liquid chamber 112 comprises a different liquid composition disposed therein, wherein liquid compositions in adjacent chambers are preferably different from each other.

[056] According to some embodiments, the liquid cartridge 110 comprises the mixing chamber 120 and the fluid control mechanism 160 disposed therein.

[057] According to some embodiments, the liquid cartridge 110 is sized so as to contain a sufficient amount of a liquid composition or mixtures thereof for a pre-determined number of inhalations or puffs by a user. After that pre-determined number of inhalations, the liquid cartridge 110 could be refilled or replaced. In some embodiments, each liquid chamber 112 can be individually refilled and optionally replaced. Furthermore, in some embodiments, the entire mouthpiece 140 can be replaced. In some embodiments, the pre-determined number of inhalations is dependent upon the desired size of the liquid cartridge 110 and the sizes of the liquid chambers 112, the sizes of the mouthpiece 140 and entire device 100, and the properties and types of the liquid compositions or mixtures to be used.

[058] According to some embodiments, the mouthpiece 140 further comprises at least one fluid path 142 configured to direct fluid flow therethrough (e.g., air, aerosols, etc.). According to some embodiments, the mouthpiece 140 comprises a plurality of fluid paths 142. In some embodiments, the fluid path 142 extends from a ventilation end 144 of the mouthpiece 140 towards the mixing chamber 120 and allows or directs fluid (e.g., air, vapors, aerosols, etc.) flow therethrough. In further embodiments, the fluid path 142 is configured to enable fluid communication between the mouthpiece 140 and the mixing chamber 120. According to some embodiments, the liquid cartridge 110 comprises at least a portion of the at least one fluid path 142.

[059] As used herein, the term "fluid communication" refers to a path which allows fluid to flow between two components, wherein said two components can be directly or indirectly joined to each other. Similarly, as used herein, the terms "fluidly coupled" or "fluidly connected" are interchangeable, and refers to a connection between two components that allows fluid to flow from one component to the other, wherein said connection may be direct or indirect via an intermediate components enabling fluid flow therethrough.

[060] According to some embodiments, housing 104 is a unitary component (see Figure 1).

[061] According to other embodiments, the housing 104 is made from at least two separate components configured to be detachably attached to each other (i.e., a main body housing 106 and a controller housing 134). According to some embodiments, the housing 104 of the device 100 comprises a main body housing 106 comprising: the liquid cartridge chamber 116 and optionally the liquid cartridge 110 disposed therein, and the mouthpiece 140 comprising at least a portion of the at least one fluid path 142. According to some embodiments, the main body housing 106 further comprises the fluid control mechanism disposed therein. According to some embodiments, the main body housing 106 further comprises the mixing chamber 120. According to some embodiments, the main body housing 106 further comprises at least one sensor 132. According to some embodiments, the housing 104 of the device 100 comprises a controller housing 134 comprising: the power source chamber 138 and optionally the power source 130 disposed therein, and the controller 150. According to some embodiments, the controller housing 134 further comprises the fluid control mechanism. According to some embodiments, the controller housing 134 further comprises the at least one sensor 132. According to some embodiments, the controller housing 134 further comprises the mixing chamber 120. [062] According to some embodiments, the controller housing 134 and the main body housing 106 are configured to be detachably attached to each other, utilizing attachment means selected from a hinge, pin, latches, snap-fit fastener, screw fittings, a hook and loop, a locking mechanism, combinations thereof, or any other attaching mechanism in the art. According to some embodiments, controller housing 134 and the main body housing 106 are electrically and/or functionally coupled to one another.

[063] According to some embodiments, the liquid cartridge 110 comprises a plurality of liquid chambers 112, wherein each liquid chamber 112 comprises a liquid composition 113 disposed therein. According to some embodiments, the liquid composition 113 disposed within each liquid chamber 112 can be identical or different from a liquid composition disposed within a following or a subsequent liquid chamber 112. Preferably, in some embodiments, each liquid chamber 112 comprises a unique liquid composition 113.

[064] According to some embodiments, the liquid composition 113 disposed within the liquid cartridge 110 comprises a plurality of cannabinoids (i.e. two or more cannabinoids) which are present in the Cannabis extract, said plurality of cannabinoids are in relative amounts which are substantially identical to their relative amounts in the Cannabis extract, thus enabling to maintain the entourage effect. In some embodiments, the plurality of cannabinoids is selected from the group consisting of cannabidivarinic acid (CBDVA), cannabidiolic acid (CBDA), cannabigerolic acid (CBGA), cannabidiol (CBD), cannabinol (CBN), cannabinolic acid (CBNA), tetrahydrocannabinol (THC), cannabichromene (CBC), cannabichromenic acid (CBCA), tetrahydrocannabinolic acid (THCA), cannabicitran, and a mixture or combination thereof. Each possibility represents a separate embodiment. In one embodiment, the plurality of cannabinoids comprises at least two of the aforementioned cannabinoids, for example 2, 3, 4, 5, 6, 7, 8, 9, 10, or all 11 cannabinoids. Each possibility represents a separate embodiment. In some embodiments, the plurality of cannabinoids further comprises at least one of tetrahydrocannabivarin (THCV), cannabigerol (CBG), sesquicannabigerol (sesqui-CBG), sesquicannabigerolic acid (sesqui-CBGA), CBGA-C4, CBG-C4, cannabigerovarinic acid (CBGVA), cannabigerivarin (CBGV), cannabigerorcinic acid (CBGOA), cannabigerorcin (CBGO), cannabigerolic acid monomethyl ether (CBGMA), cannabigerol monomethyl ether (CBGM), cannabicyclol (CBL), cannabicyclolic acid (CBLA), THCA-C4, THC-C4, tetrahydrocannabivarin carboxylic acid (THCVA), tetrahydrocannabivarin (THCV), tetrahydrocannabiorcolic acid (THCOA), tetrahydrocannabiorcol (THCO), THCMA, THCM, CBDA-C4 , CBD-C4, cannabidiorcolic acid (CBDOA), cannabidiorcol (CBDO), cannabidiolic acid monomethyl ether (CBDMA), cannabidiol monomethylether (CBDM), cannabichromenic acid (CBCA), cannabichromene (CBC), cannabichromevarinic acid (CBCVA), cannabichromevarin (CBCV), cannabiorchromenic acid (CBCOA), cannabiorchromene (CBCO), cannabinolic acid (CBNA), cannabinol (CBN), cannabinol-C4 (CBN-C4), cannabivarinic acid (CBNVA), cannabivarin (CBNV), cannabiorcolic acid (CBNOA), cannabiorcol (CBNO), CBNA-8-OH, CBN-8-OH, cannabinol methylether (CBNM), cannabielsoin acid (CBEA), cannabielsoin (CBE), cannabielsoic acid (CBEVA), cannabielsoin (CBEV), cannabinodiolic acid (CBNDA), cannabinodiol (CBND), cannabinodivarinic acid (CBNDVA), (-)-A ⁸ -trans-tetrahydrocannabinol (A ⁸ -THC), cannabitriol-1 (CBT-1), CBT-2, CBT-3, CBTA-1, CBTA-3, cannabitriolvarin (CBTV), CBTV-3, and a mixture or combination thereof. Each possibility represents a separate embodiment.

[065] According to some embodiments, the liquid composition 113 within each liquid chamber 112 comprises at least one type or strand of cannabinoid, or a plurality of strands of cannabinoids, as disclosed above. According to some embodiments, the liquid composition 113 within each liquid chamber 112 comprises different strands or types of cannabinoids, relative to other liquid chambers 112 disposed within the liquid cartridge 110. According to some embodiments, the liquid composition within each liquid chamber 112 comprises different combinations or mixtures of cannabinoids. According to some embodiments, the liquid composition within each liquid chamber 112 comprises different pluralities of cannabinoids.

[066] According to some embodiments, the liquid composition 113 within each liquid chamber 112 further comprises other components extracted from a plant in the genus Cannabis, for example at least one of terpenes, terpenoids, flavonoids, nitrogenous compounds, amino acids, proteins, glycoproteins, sugars, hydrocarbons, fatty acids, esters, lactones, steroids, noncannabinoid phenols, and a mixture or combination thereof. Each possibility represents a separate embodiment. [067] According to some embodiments, the liquid composition 113 within each liquid chamber 112 comprises one or more materials selected from the group consisting of: tobacco, nicotine, caffeine, at least one type of essential oil, at least one type of cannabinoid, water, flavoring material, an aerosol former substance, and combinations thereof. Each possibility represents a separate embodiment. According to some embodiments, the aerosol former substance comprises propylene glycol (PG), vegetable glycol (VG), other suitable substances known in the art, and combination thereof.

[068] According to some embodiments, the fluid control mechanism disposed within the vaporization device 100 is a fluid control mechanism 160. According to some embodiments, fluid control mechanism 160 is configured to transfer or draw or wick a predetermined volume (e.g., a dose) of a liquid composition from the liquid cartridge 110, via one or more transferring elements 165, and to deliver or transfer it to the mixing chamber 120, in a liquid (optionally heated) or vapor state.

[069] According to some embodiments, the fluid control mechanism 160 comprises one or more transferring elements 165, wherein the liquid cartridge 110 comprises one or more liquid chambers 112, and wherein each transferring element 165 is connected to each liquid chamber 112 at one end and to the mixing chamber 120 in the other end, as illustrated for example in Figures 2 and 3. According to some embodiments, the fluid control mechanism 160 comprises a plurality of transferring elements 165, wherein the liquid cartridge 110 comprises a plurality of liquid chambers 112, and wherein each transferring element 165 is connected or coupled to a corresponding liquid chamber 112 at one end thereof and to the mixing chamber 120 in the other end thereof.

[070] According to some embodiments, each transferring element 165 extends from a first end 161 towards a second end 162, and defines a lumen 164 extending therebetween. In some embodiments, the first end 161 of transferring element 165 is in fluid communication or is connected to its corresponding liquid chamber 112. In some embodiments, the second end 162 of transferring element 165 is in fluid communication or is connected to the mixing chamber 120, or to an entrance thereof. In some embodiments, the first end 161 of transferring element 165 is extending into the liquid chamber 112, the second end 162 thereof is extending into the mixing chamber 120, and a portion of lumen 164 is directly or indirectly connected to at least one flow inducing element 163.

[071] According to some embodiments, each liquid chamber 112 is connected to a corresponding transferring element 165, wherein at least a portion of the corresponding transferring element 165 (e.g., lumen 164) is disposed within the liquid chamber 112 (see Figures 9C, 11A, and 12 below). In other embodiments, each liquid chamber 112 is connected to a corresponding transferring element 165, wherein at least a portion of the corresponding transferring element 165 (e.g., lumen 164) is located externally to each liquid chamber 112 (not shown).

[072] According to some embodiments, at least a portion of lumen 164 is directly or indirectly connected to at least one flow inducing element 163, as illustrated in Figure 2. According to some embodiments, the flow inducing element 163 is at least one heating element 166. According to some embodiments, a first portion 164A of lumen 164 is directly or indirectly connected to a first heating element 167, and a second portion 164B of lumen 164 is directly or indirectly connected to a second heating element 168, as illustrated in Figure 3.

[073] According to some embodiments, the liquid cartridge 110 comprises a plurality of liquid chambers 112, and the fluid control mechanism 160 comprises a plurality of transferring elements 165 and a plurality of heating elements 166, such that each transferring element 165 is fluidly coupled/connected to each corresponding liquid chamber 112 at the first end 161 thereof, and fluidly coupled/connected to the mixing chamber 120 at the second end 162 thereof. In further such embodiments, at least a portion of each lumen 164 of each transferring element 165 is directly or indirectly connected to at least one corresponding heating element 166.

[074] According to some embodiments, the liquid cartridge 110 or portions thereof (e.g., each liquid chamber 112) comprises at least one insulating layer 114, optionally located at a bottom portion thereof (or at other portions), configured to prevent or reduce the amount of heat emitted by heating element 166 that might be transferred therefrom towards the liquid cartridge 110 or portions thereof, in order to protect the liquid composition(s) disposed therein. In some embodiments, the insulating layer 114 comprises an insulating material or layer configured to maintain a stable temperature range of the liquid composition(s) disposed within the liquid cartridge 110, and to prevent or reduce external thermal affects (e.g., heat emitted by heating element 166). The insulating material or layer comprises one or more materials selected from but not limited to, plastics, ceramics, or a combination of materials with heat dissipating and heat isolation properties. Each possibility represents a different embodiment.

[075] According to some embodiments, a portion of the liquid composition 113 is transferred from each liquid chamber 112 to the first end 161 of each corresponding transferring element 165, then to the second end 162 thereof and into the mixing chamber 120 by capillary action, which can be expedited by the actuation of each heating element 166 which enable to provide thermal energy (e.g., heat) to each corresponding transferring element 165.

[076] According to some embodiments, each heating element 166 is configured to produce thermal energy, and to apply or transfer at least a portion of said thermal energy (e.g., heat) to the liquid composition disposed within or transferring through each corresponding transferring element 165 or portions thereof (e.g., lumen 164), in order to enable the heating or evaporation thereof.

[077] According to some embodiments, the operating temperature of each heating element 166 is optionally selected from the range of about 80-350 °C. According to further embodiments, the operating temperature of each heating element 166 can be below 80 °C and/or above 350 °C.

[078] According to some embodiments, each heating element 166 is surrounding or enveloping the transferring element 165 or portions thereof (e.g., lumen 164). According to some embodiments, heating element 166 is in the form of a coil surrounding the transferring element 165 or portions thereof (e.g., lumen 164) (not shown). In some embodiments, heating element 166 is in the form of a box directly contacting the transferring element 165 or portions thereof (e.g., lumen 164), as illustrated at Figure 2. It is to be understood, however, that heating element 166 can be in any other suitable form, such as a sphere, cylinder, tube, coil, or any other polyhedron in the art. [079] According to some embodiments, each transferring element 165 is made from a material which enables to transfer thermal energy (i.e., heat) therethrough, such as for example a metal or metal alloy, a polymer or polymer blend, and combinations thereof. According to some embodiments, transferring element 165 is configured to enable to transfer heat therethrough from the heating element to the liquid composition disposed therein. In some embodiments, transferring element 165 can be made from stainless steel, aluminum, other suitable metals, and combinations thereof.

[080] According to some embodiments, each transferring element 165 is rigid. According to some embodiments, each transferring element 165 is in a form of an elongated rigid tube or channel, and has a diameter DI. In some embodiments, transferring element 165 is a microchannel. In some embodiments, transferring element 165 is a rigid microchannel. In some embodiments, transferring element 165 is a tubular microchannel. In some embodiments, the cross-sectional shape of transferring element 165 is circular. It is to be understood however that the cross-sectional shape of transferring element 165 may be different and still have the same properties and utilities, such as for a non-limiting example: a square, triangle, elliptical, or any other polygon shape in the art.

[081] As used herein, the term "elongated" refers to a member that the long dimension thereof (e.g., length) is greater than the short dimension (e.g., width or diameter) thereof. For example, the length of said microchannel may be at least three times, at least five times, at least ten times, or more, greater than of the width or diameter thereof.

[082] According to some embodiments, the diameter DI of each transferring element 165 is selected from the range of about 1 pm - 1000 pm. According to further embodiments, the diameter DI of each transferring element 165 is selected from the range of about 1 pm - 10 pm, 10 pm - 100 pm, 100 pm - 200 pm, 200 pm - 300 pm, 300 pm - 400 pm, 400 pm - 500 pm, 500 pm - 600 pm, 700 pm - 800 pm, 800 pm - 900 pm, or 900 pm - 1000 pm. Each possibility represents a different embodiment. According to some embodiments, the diameter DI of each transferring element 165 is selected from the range of about 10 pm - 1000 pm. [083] According to some embodiments, each transferring element 165 has a length LI defined between the first end 161 and the second end 162 thereof (see Figure 2). In further embodiments, the length LI is selected from the range of about 50 |am - 25 mm. In still further embodiments, the length LI is selected from the range of about 0.1 mm - 15 mm. In yet still further embodiments, the length LI is selected from the range of about 1 mm - 10 mm.

[084] According to some embodiments, each transferring element 165 has an inner volume selected from the range of about 1 nanoliter - 100 microliters. In further embodiments, the inner volume of each transferring element 165 is selected from the range of about 1 - 1000 nanoliters. In still further embodiments, the inner volume of each transferring element 165 is selected from the range of about 10 - 500 nanoliters. In yet still further embodiments, the inner volume of each transferring element 165 is selected from the range of about 20 - 200 nanoliters.

[085] It is contemplated, in some embodiments, that the volume of each transferring element 165, which is dependent upon the length LI and diameter DI thereof, enables to control the amount of the liquid composition which is being wicked or transferred therethrough, from each corresponding liquid chamber 112 towards the mixing chamber 120. In some embodiments, the volume of the liquid composition which is being wicked or transferred or delivered through each transferring element 165 and into the mixing chamber 120 (e.g., a predetermined dose) corresponds to the volume of each corresponding transferring element 165 and is dependent upon the flow rate of the liquid composition flowing therethrough.

[086] As used herein, the term "predetermined dose" refers to the total volume of the liquid composition which flows from each liquid chamber 112 through each corresponding transferring element 165 and into the mixing chamber 120 for one inhalation event by the user. In such cases, the predetermined dose is dependent upon the flow rate of the liquid through each transferring element 165 and the volume of the transferring element 165, wherein the flow rate is dependent upon the amount of thermal energy applied by the heating element 166 thereto (e.g., the temperature thereof). Alternatively, if the liquid composition within or passing through each transferring element 165 is heated to the point of evaporation into the mixing chamber, the term "dose" refers to the total volume of the liquid composition which was evaporated for one inhalation event by the user. In such cases, the predetermined dose is dependent upon the number of times the liquid composition within each transferring element 165 was evaporated, wherein the evaporation is dependent upon the amount of thermal heating energy applied by the heating element 166 thereto.

[087] As used herein, the term "inhalation event" refers to a single inhalation by a user, wherein the user inhales the vapor and/or aerosol content from within the mixing chamber 120.

[088] According to some embodiments, it is contemplated that the amount of thermal heating energy which is applied by each heating element 166 to the liquid composition disposed within (or transferring through) each corresponding transferring element 165, enables to control the amount of the material which is being wicked or transferred into the mixing chamber 120 and the flow rate thereof, and further defines the liquid or vapor state thereof. For example, a relative medium amount of heating energy will reduce the viscosity and/or capillary forces residing within the liquid disposed within each transferring element 165, thus advantageously enabling to the liquid to easily flow into the mixing chamber in liquid form. A higher amount of heating energy will result in the evaporation of the liquid disposed within each transferring element 165, thus enabling to transfer vapors into the mixing chamber therefrom. The amount of thermal heating energy can be predetermined or customized according to input from the user, and are dependent upon the types of liquid compositions disposed within each liquid chamber 112, and their different properties (viscosities, boiling points, etc.).

[089] According to some embodiments, each transferring element 165 is configured to enable fluid flow therethrough, and thus to enable fluid communication between each liquid chamber 112 and the mixing chamber 120. According to some embodiments, it is suggested that the combination between the volume of each transferring element 165 and the amount of thermal energy applied from each corresponding at least one heating element 166 thereto, can define the amount of liquid or vapor (i.e., “dose”) which is being transferred therethrough, from each corresponding liquid chamber 112 into the mixing chamber 120. Advantageously, said combination enables to control the dosage from each liquid chamber 112 which is transferred into the mixing chamber 120 and to form various liquids or vapors mixtures therein, and thus to maintain the entourage effect of various cannabinoids mixtures as disclosed herein above. [090] According to some embodiments, the mixing chamber 120 comprises at least one heating element 169 (Figure 1), which can be identical or different to each heating element 166. Said heating element 169 can be used to enable the heating and evaporation of a liquid mixture disposed within the mixing chamber 120, thereby enabling the formation of aerosols therein. In some embodiments, the at least one heating element 169 is configured to enable the transformation of the liquid mixture disposed within the mixing chamber 120 into a vapor mixture. In some embodiments, the at least one heating element 169 is configured to receive power from the at least one power source 130 and is operatively connected to the controller 150.

[091] According to some embodiments, the fluid control mechanisms of the present invention (e.g., fluid control mechanism 160) can be activated by an input from a user (e.g., pressing a button, inhalation by the user, or a combination of both). The vaporization device 100 can be activated by the user drawing/puffing air into the device via the at least one fluid path 142 of the mouthpiece 140, and the inhalation being detected by a sensor 132 (e.g., one or more pressure sensors or other types of sensors) which transmit information to the controller 150. Alternatively or additionally, vaporization device 100 can be activated by the user pressing or activating a user interaction portion of the device.

[092] According to some embodiments, activation of the fluid control mechanism 160 comprises the controller 150 sensing the inhalation by the user (via a sensor 132) and/or receives the user’s input and as a result activates the plurality of heating element 166. The power source 130 supplies a pulse of energy to each heating elements 166 to heat each lumen 164 of each corresponding transferring element 165. The liquid disposed within each transferring element 165 is heated or vaporized by the heating element 166, to create a heated liquid or vapor therein, respectively. The heated liquid or vapor flows or evaporates into the mixing chamber 120, to from a liquid mixture or vapor mixture therein, respectively. At the same time, the liquid being vaporized or heated is replaced by further liquid moving towards the second end 162 of transferring element 165 by capillary action.

[093] According to some embodiments, the heated vapor of each transferring element 165 is transferred into the mixing chamber 120, to from a mixture of vapors, and then optionally mixed with air flowing thereto from the at least one fluid path 142 and/or from at least one air intake path of the device 100. In the mixing chamber 120, the vapor condenses to form an inhalable aerosol, which is carried towards the mouthpiece 140 and into the mouth of a user via the at least one fluid path 142.

[094] According to alternative embodiments, the heated liquid at each transferring element 165 is transferred into the mixing chamber 120, to from a mixture of liquids therein. The least one heating element 169 disposed within the mixing chamber 120 can generate the evaporation thereof to create heated vapors therein, which are then mixed with air flowing thereto, and condenses to form inhalable aerosols, which is then carried towards the mouthpiece 140 and into the mouth of a user via the at least one fluid path 142. The air flows into the mixing chamber 120 from the at least one fluid path 142 and/or from at least one air intake path of the device 100.

[095] Thus, in some embodiments, the vaporization devices of the present invention (e.g., vaporization device 100) can be used for providing customized mixtures of aerosols for inhalation by a user, wherein said customized mixtures can have various therapeutic effects used for various forms of medical applications. In some embodiments, the customized mixtures can be used for treating or suppressing a disease or a disorder selected from cancer, chronic pain, migraine, other relevant conditions, and a combination thereof. In further embodiments, the customized mixtures can be used for the treatment of chronic pain. In further embodiments, the customized mixtures can be used for the treatment of migraines. In further embodiments, the customized mixtures can be used for treating or suppressing a disease or a disorder, such as various forms of cancer.

[096] As used herein, the terms “treating” and “treatment” refer to a method of alleviating or abrogating a disease and/or its attendant symptoms.

[097] Typical wicking materials of known vaporization devices include porous or capillary materials including ceramics, cotton, and graphite-based materials in the form of fibers or sintered powders. In some embodiments, the fluid control mechanism 160 of the present invention comprises a plurality of elongated rigid transferring elements 165 (corresponding to the number of liquid chambers 112) in the form of microchannels or tubes having known predetermined volumes, having a corresponding plurality of heating elements 166 being in direct or indirect contact with each lumens thereof. Advantageously, this configuration of the fluid control mechanism 160 as disclosed herein above, allows to control and create various liquid or vapor mixtures suitable for various inhalable applications, according to the types and properties of the desired materials for consumption (e.g., various cannabinoids mixtures), which cannot be achieved with the previously known wicking materials and vaporization devices in the art.

[098] According to some embodiments, the power source 130 comprises at least one battery. According to some embodiments, the power source 130 comprises a plurality of batteries. According to some embodiments, power source 130 is selected from: nickel cadmium (NiCd) battery, lithium-ion (Li-ion) battery, lithium-ion polymer (Li-ion polymer) battery, lead-acid battery, nickel-metal hydride (NiMH) battery, combination thereof, and other known batteries in the art. Each possibility represents a separate embodiment. According to some embodiments, power source 130 is configured to be electronically connected, directly or indirectly, to the other electrical elements accommodated within device 100 (e.g., the controller and the plurality of flow inducing elements), and to provide electric power thereto. According to some embodiments, power source 130 is rechargeable and can be recharged/charged via one or more of: induction charging, a wall electrical outlet, a USB to a computer charging outlet, and the like. According to some embodiments, power source 130 is replaceable and can be extracted from the power source chamber 138 and replaced with a new fully charged power source.

[099] According to some embodiments, the power source 130 is in electrical and/or operative communication with the controller 150 and the plurality of flow inducing elements 163 (e.g., heating elements 166).

[0100] According to some embodiments, controller 150 is in electrical and/or operative communication with at least one of the other electrical elements accommodated within the device 100. According to some embodiments, controller 150 comprises at least one processor configured to send and receive data (such as, but not limited to, digitized signals, data, etc.) to and from the various electronic components of device 100. The at least one processor of controller 150 can be selected from, but not limited to, a microprocessor, a microcontroller, a Digital Signal Processor (DSP), an Application Specific Integrated Circuit (ASIC), a Field Programmable Gate Array (FPGA), a Programmable Logic Device (PLD), a controller, a state machine, gated logic, discrete hardware components, or any other suitable device or a combination of devices that can perform calculations or other manipulations of information. Each possibility represents a separate embodiment. According to some embodiments, controller 150 is mounted on at least one printed circuit board (PCB).

[0101] The term “processor”, as used herein, refers to a single chip device which includes a plurality of modules which may be collected onto a single chip in order to perform various computer-related functions. According to some embodiments, controller 150 is programmable.

[0102] According to some embodiments, controller 150 and/or the PCB its mounted on may further include one or more of a memory unit, a timer, and other suitable electrical components. In some embodiments, the electronics of the PCB and/or controller 150 is composed of a synthetic material that is thin and flexible, which enables to conform to the shape of the device 100.

[0103] According to some embodiments, controller 150 comprises a power source controller 152 embedded therein or embedded within the same PCB (not shown), or as a separate component (see Figure 1), wherein said controller 152 is configured to transfer and/or regulate/balance electric power from the power source 130 to the plurality of flow inducing element 163, or optionally to each flow inducing element 163 separately. According to some embodiments, the power source controller 152 comprise a battery management system (BMS) which is configured to protect the power source 130 during charging and discharging thereof. The power source controller 152 can perform at least one function, such as to prevent or balance over charge/discharge of the power source 130; to regulate the electric current transferring from the power source 130 to the plurality of flow inducing element 163 or to each flow inducing element 163; to regulate/control the temperature of the power source 130 during charging and discharging thereof; to cool the power source 130 during the utilization thereof, or a combination thereof. Advantageously, the utilization of the power source controller 152 can provide a prolonged life cycle for the power source 130, and/or to enhance electric power transfer therefrom. According to some embodiments, the power source controller 152 is in electrical and/or operative communication with the controller 150 and/or the power source 130.

[0104] According to some embodiments, the controller 150 is configured to control the production of energy by each flow inducing element 163 (e.g., heating element 166) applied to each corresponding transferring element 165, wherein the amount of energy is configured to facilitate the flow of the predetermined dose of liquid drawn from each liquid chamber 112 or to transform said liquid into vapor. According to some embodiments, controller 150 is in electrical and/or operative communication with the one or more heating elements 166, wherein the controller 150 controls the activation of the fluid control mechanism 160 by adjusting/controlling the amount of heating energy that is being transferred therefrom to each corresponding transferring element 165 as disclosed above.

[0105] According to some embodiments, device 100 comprises a plurality of controllers 150, wherein each controller 150 is in electrical and/or functional communication with each heating element 166, and wherein each controller 150 controls and/or adjusts the amount of heating energy that is being transferred from its corresponding heating element 166 to each corresponding transferring element 165.

[0106] According to some embodiments, device 100 further comprises at least one sensor 132 (see Figure 1) selected from but not limited to, a pressure sensor, an air-flow sensor, other suitable sensors, and combinations thereof. The sensor 132 can be disposed within the mouthpiece 140 and/or the controller housing 134, and is in electrical and/or operative communication with the controller 150.

[0107] The controller 150 can be used to manage the operation of device 100. In some embodiments, when the controller 150 senses the user inhaling (optionally via sensor 132), it can adjust the amount of energy applied by each heating element 166 to each corresponding transferring element 165, by controlling the activation of the power source 130 and/or the power transfer therefrom to each heating element 166. In further such embodiments, the power source 130 supplies a current pulse of a pre-determined time to each heating element 166, and optionally to the heating element 169 disposed within the mixing chamber 120. The pre- determined time for the current pulse will determine the amount of heating energy which is being applied by each heating element 166 to each corresponding transferring element 165, and is depended on the amount of liquid composition required for a single inhalation (e.g., the dose), and the time taken for that amount of liquid to be heated or vaporized. That will, in turn, depend on: the type(s) of the liquid composition(s) disposed within each liquid chamber 112 and their properties (boiling point, viscosity, etc.), and the volume of each transferring element 165. The pre-determined time may be between about 0.1 and about 60 seconds, or preferably between about 0.1 and about 10 seconds. The pre-determined time may be in a time range suitable for the user to comfortably draw air into the device.

[0108] According to some embodiments, the controller 150 and the power source 130, and optionally sensor 132, together control the amount of thermal energy (e.g., by controlling the temperature and timing of heating) which is being applied by each heating element 166 to each corresponding transferring element 165. In this way, for each liquid chamber 112, a corresponding transferring element 165 may enable to heat or vaporize a different liquid composition 113, which can be vaporized or heated at a specific temperature suitable to the materials disposed therein. Advantageously, the amount of the liquid or vapor (i.e., the dose) which is being wicked or transferred, accordingly, into the mixing chamber 120 from each liquid chamber 112 can be controlled, in order to achieve an ideal mixture within the mixing chamber 120 and to maintain the entourage effect of various cannabinoids mixtures as disclosed herein above. Furthermore, the activation of the fluid control mechanism 160 as disclosed above prevents over-heating, creating toxins and bad tastes, and allows to form personalized or specific cannabinoids mixture in order to achieve desired therapeutic effects.

[0109] According to some embodiments, the housing 104 of the device 100 (or optionally the controller housing 134) further comprises a user interaction portion 136 (see Figure 1) comprising one or more of a button, a touch screen, a display screen, LED lights, and combinations thereof. Each possibility represents a different embodiment. In some embodiments, the user can use the interaction portion 136 to initiate the activation of the device 100 and/or to control the activation thereof. The user interaction portion 136 may further comprise at least one control switch in the form of an on/off push button switch. As used herein, the terms “on/off push button switch” or “push button switch” are interchangeable, and refers to a two-position, ‘on/off’ switch mechanism, wherein a first press of the push button switch actuates the switch from ‘off’ to ‘on’ and activates the various components of device 100, while a second press of the push button switch turns the switch back ‘off’ and deactivates the various components thereof.

[0110] According to some embodiments, the user interaction portion 136 is in operative communication with the controller 150, wherein the user interaction portion 136 is configured to provide to the controller 150 signals indicative of the amount of energy for each transferring element 165, based on input received by the user. In further embodiments, the controller 150 is configured to adjust the amount of energy applied to each transferring element 165 by each corresponding heating element 166, according to one or more predetermined liquid mixture formulas stored therein and/or according to input received by the user via the user interaction portion 136.

[0111] According to some embodiments, the controller 150 can be configured to store data programmed by the user and/or preprogrammed by a manufacturer. According to some embodiments, the controller 150 can be configured to store: temperature information for the liquid composition(s) 113 of each liquid chamber 112, cannabinoids mixtures formulas corresponding to different therapeutic effects, user preferences and information, and the like. In some embodiments, the user can directly control or adjust a specific cannabinoids mixture in order to achieve a desired therapeutic effect, by controlling the activation of the fluid control mechanism 160 as disclosed herein above, via the interaction portion 136. Furthermore, in some embodiments, the user can choose between different preprogrammed cannabinoids mixtures options stored within the controller 150, via the user interaction portion 136, corresponding to the liquid compositions 113 disposed within the liquid cartridge 110.

[0112] In some embodiments, the device 100 may include at least one communication device 155 (e.g. a USB port, Bluetooth, Wi-Fi, etc.) capable of connecting to an external computing device (e.g., a PC, smartphone, or any other computing device) through a wired or wireless connection. In some embodiments, the communication device 155 comprises a wireless communication module, which is optionally embedded within the controller 150, wherein said module is configured to enable wireless communication via known wireless protocols, such as but not limited to, Bluetooth, Wi-Fi, and the like. In some embodiments, the communication device 155 comprises a USB port configured to enable a wired connection between the controller 150 and an external computing device (e.g., a PC, smartphone, etc.). According to some embodiments, the controller 150 can be configured to communicate with a remote storage (e.g., cloud storage), through the communication device 155, in order to transfer and/or receive various forms of information and updates. In this way, the temperature of each heating element 166 could be more closely monitored and adjusted for more accurate vaporization or heating.

[0113] Reference is now made to Figures 4-5C. Figure 4 illustrates a cross sectional view of a portion of the liquid cartridge 110 and a portion of a fluid control mechanism 260, according to some embodiments. Figure 5A illustrates a bottom view of a portion of the liquid cartridge 110 and a portion of the fluid control mechanism 260 of Figure 4, according to some embodiments. Figure 5B illustrates a cross sectional view in perspective of a portion of the liquid cartridge 110 and the fluid control mechanism 260 taken from line 5B-5B of Figure 5A, according to some embodiments. Figure 5C illustrates a bottom view of a portion of the liquid cartridge 110 and a portion of the fluid control mechanism 260, according to some embodiments.

[0114] Fluid control mechanism 260 of Figures 4-5C is similar to fluid control mechanism 160 of Figures 1-3, and therefore share many common features as can be appreciated by the skilled in the art. Specific features or components are described below.

[0115] Thus, Figures 4-5C shows exemplary alternative implementations of some components of the fluid control mechanism. Specifically, fluid control mechanism 260 shows a circumferential heating element 266.

[0116] According to some embodiments, the fluid control mechanism disposed within the vaporization device 100 is a fluid control mechanism 260.

[0117] According to some embodiments, fluid control mechanism 260 comprises a plurality of circumferential heating elements 266, wherein each one is at least partially surrounding or encompassing at least a portion of each corresponding transferring element 165 or portions thereof (e.g., lumen 164). In some embodiments, each lumen 164 (or a portion thereof) of each transferring element 165 is disposed within the circumferential heating element 266. In some embodiments, each circumferential heating element 266 is in direct or indirect contact with each corresponding transferring element 165. In some embodiments, the circumferential heating element 266 is a cylindric or a ring-shaped heating element, as illustrated at Figure 5B. In some embodiments, the circumferential heating element 266 is U-shaped, as illustrated at Figure 5C. It is to be understood, however, that circumferential heating element 266 can be in any other suitable form, such as a sphere, ellipsoid, box, or any other polyhedron in the art. Advantageously, the circumferential heating element 266 can provide an effective and uniform heat transfer therefrom to the transferring element 165 or portions thereof and to the liquid disposed therein.

[0118] According to some embodiments, the circumferential heating element 266 comprises an insulating portion 268 configured to enable electric current transfer through the heating element 266, in order to enable the heating thereof. The insulating portion 268 can be shaped as a sector configured to correspond to or fit in the cylindric-shaped circumferential heating element 266, as illustrated at Figure 5B. The insulating portion 268 can be shaped as a segment of the cylindric-shaped circumferential heating element 266 (not shown). The insulating portion 268 can be shaped as a box or rectangle configured to correspond to or fit in the U- shaped circumferential heating element 266, as illustrated at Figure 5C. It is to be understood, however, that the insulating portion 268 can be in any other suitable form, such as a sphere, ellipsoid, box, or any other polyhedron in the art.

[0119] Reference is now made to Figures 6A-B, illustrating a cross sectional view and a cross sectional view in perspective, respectively, of a portion of the liquid cartridge 110 and a portion of a fluid control mechanism 360, according to different embodiments.

[0120] Fluid control mechanism 360 of Figures 6A-B is similar to fluid control mechanism 260 of Figures 4-5B or fluid control mechanism 160 of Figures 1-3, and therefore share many common features as can be appreciated by the skilled in the art. Specific features or components are described below. [0121] Thus, Figures 6A-B shows exemplary alternative implementations of some components of the fluid control mechanism. Specifically, fluid control mechanism 360 shows a porous transferring element 365.

[0122] According to some embodiments, the fluid control mechanism disposed within the vaporization device 100 is a fluid control mechanism 360.

[0123] According to some embodiments, fluid control mechanism 360 comprises a plurality of porous transferring elements 365 wherein each one extends from a first end 361 towards a second end 362, and defines a middle portion 364 extending therebetween. In some embodiments, the first end 361 of porous transferring element 365 is fluidly coupled/connected to the liquid chamber 112, the second end 362 thereof is fluidly coupled/connected to the mixing chamber 120, and the middle portion 364 thereof is directly or indirectly connected to at least one heating element 366. According to some embodiments, at least one heating element 366 is directly or indirectly connected to porous transferring element 365 and is configured to transfer heat thereto. The heating element 366 can be identical to heating element 166.

[0124] According to some embodiments, the liquid cartridge 110 comprises a plurality of liquid chambers 112 and fluid control mechanism 360 comprises a plurality of porous transferring elements 365, wherein each porous transferring element 365 is fluidly coupled/connected to each corresponding liquid chambers 112 at the first end 361 thereof, and fluidly coupled/connected to the mixing chamber 120 at the second end 362 thereof. In further such embodiments, at least a portion of each porous transferring element 365 is directly or indirectly connected to each corresponding at least one heating element 366.

[0125] According to some embodiments, a first portion of porous transferring element 365 is directly or indirectly connected to a first heating element 367, and a second portion thereof is directly or indirectly connected to a second heating element 368, as illustrated in Figure 6A.

[0126] According to alternative embodiments, the heating element 366 is a circumferential heating element 369 which at least partially surrounds or encompasses the porous transferring element 365 or portions thereof (e.g., middle portion 364). In some embodiments, the circumferential heating element 369 is a cylindric or ring-shaped heating element, as illustrated at Figure 6B. It is to be understood, however, that circumferential heating element 369 can be in any other suitable form, such as a sphere, ellipsoid, box, or any other polyhedron in the art. Advantageously, the circumferential heating element 369 can enable to provide an effective and uniform heat transfer therefrom to the porous transferring element 365 or portions thereof, and to the liquid disposed therein. The circumferential heating element 369 can be identical to the circumferential heating element 266.

[0127] According to some embodiments, each porous transferring element 365 is made from a porous material comprising interconnected pores. According to some embodiments, each porous transferring element 365 has an interconnected porous structure characterized by an inner volume, wherein the inner volume selected from the range of about 1 nanoliter - 100 microliters. In further embodiments, the volume is selected from the range of about 1 - 1000 nanoliters. In still further embodiments, the volume is selected from the range of about 10 - 500 nanoliters. In yet still further embodiments, the volume is selected from the range of about 20 - 200 nanoliters. According to preferred embodiments, the interconnected porous inner volume of porous transferring element 365 is identical to the volume of the microchannel transferring element 165, and therefore can similarly enable to control the amount of the liquid composition which is being wicked or transferred or delivered therethrough, from each liquid chamber 112 towards the mixing chamber 120.

[0128] As used herein, the term "interconnected pores" refers to a three dimensional (3D) porous structure of the transferring element 365, in which all of its pores are connected to each other to form an inner volume or void space within the material, thus enabling access for liquids from the exterior of the transferring element 365 to the bulk volume thereof, resulting in fluid communication therethrough.

[0129] According to some embodiments, the porous transferring element 365 is made from a material which enables to transfer heat therethrough, such as for example a metal or metal alloy, a polymer or polymer blend, ceramics, and combinations thereof.

[0130] According to some embodiments, porous transferring element 365 is rigid. [0131] According to some embodiments, it is suggested that the combination between the interconnected porous inner volume of each porous rigid transferring element 365 and the amount of heating energy which is being transferred from each corresponding heating element 366 thereto, can define the amount of liquid or vapor (i.e., the dose) which is being transferred therethrough, from each corresponding liquid chamber 112 into the mixing chamber 120. Advantageously, said combination enables to control the dosage from each liquid chamber 112 to be transferred into the mixing chamber 120 and to form various liquids or vapors mixtures therein, and thus to maintain the entourage effect of various cannabinoids mixtures as disclosed herein above, similarly to the utilization of fluid control mechanism 160 featuring transferring element 165. Therefore, it should be understood that the utilization and purpose of porous transferring element 365 are identical or similar to those of transferring element 165, as disclosed herein above.

[0132] Reference is now made to Figures 7A-B, illustrating a cross sectional view and a cross sectional view in perspective, respectively, of a portion of the liquid cartridge 110 and a portion of a fluid control mechanism 460, according to some embodiments.

[0133] Fluid control mechanism 460 of Figures 7A-B is similar to fluid control mechanism 160 of Figures 1-3, and therefore share many common features as can be appreciated by the skilled in the art. Specific features or components are described below.

[0134] Thus, Figures 7A-B shows exemplary alternative implementations of some components of the fluid control mechanism. Specifically, fluid control mechanism 460 shows a piezo electric element 466.

[0135] According to some embodiments, the fluid control mechanism disposed within the vaporization device 100 is a fluid control mechanism 460.

[0136] According to some embodiments, fluid control mechanism 460 comprises a plurality of transferring elements 465, wherein each one extends from a first end 461 towards a second end 462 along a perpendicular axis 401, and defines a lumen 464 extending therebetween. In some embodiments, the first end 461 of each transferring element 465 is fluidly coupled/connected to each corresponding liquid chamber 112, each second end 462 thereof is fluidly coupled/connected to the mixing chamber 120, and each lumen 464 thereof is in direct or indirect contact with at least one corresponding flow inducing element 467. In some embodiments, each flow inducing element 467 is a piezoelectric element 466.

[0137] According to some embodiments, each at least one piezoelectric element 466 is configured to produce vibration energy (e.g., an acoustic shockwave). According to some embodiments, each at least one piezoelectric element 466 is in direct or indirect contact with each corresponding transferring element 465 and is configured to repeatedly displace at least a portion of an external wall 463 of each transferring element 465 along a longitudinal direction (i.e., vertically to the perpendicular axis 401).

[0138] According to some embodiments, a portion of the liquid composition 113 is transferred from each liquid chamber 112 to the first end 461 of each corresponding transferring element 465, then to the second end 462 thereof by capillary action, wherein the actuation of each corresponding piezoelectric element 466 is configured to generate (or expedite) the formation of droplets being transferred or flowing into the mixing chamber 120 therefrom.

[0139] According to some embodiments, each at least one piezoelectric element 466 is in direct contact with each corresponding transferring element 465 or portions thereof, e.g., wall 463 of lumen 464 (see Figures 7A-B). According to alternative embodiments, each at least one piezoelectric element 466 is in indirect contact with each corresponding transferring element 465, wherein each piezoelectric element 466 comprises an elongated member (e.g., a rod or a bar) configured to contact the wall 463 of each corresponding transferring element 465 and to generate the displacement thereof during actuation of the piezoelectric element 466 (not shown).

[0140] The term "longitudinal" refers to a direction, orientation, or measurement that is perpendicular to the perpendicular axis 401 (see Figure 7A).

[0141] According to some embodiments, the liquid cartridge 110 comprises a plurality of liquid chambers 112 and fluid control mechanism 460 comprises a plurality of transferring elements 465, wherein each transferring element 465 is fluidly coupled/connected to each corresponding liquid chamber 112 at the first end 461 thereof, and fluidly coupled/connected to the mixing chamber 120 at the second end 462 thereof. In further such embodiments, at least a portion of each transferring element 465 is in direct contact with each corresponding at least one piezoelectric element 466.

[0142] According to some embodiments, transferring element 465 is an elongated fluid conduit or a tube. In some embodiments, the cross-sectional shape of transferring element 465 is circular, as illustrated at Figure 7B. It is to be understood however that the cross-sectional shape of transferring element 465 may be different and still have the same properties and utilities, such as for a non-limiting example: a square, triangle, elliptical, or any other polygon shape in the art.

[0143] According to some embodiments, each transferring element 465 is made from a resilient flexible material configured to enable the displacement thereof along the longitudinal direction towards the liquid composition disposed therein (i.e., “inwards”), when a pressure or stress gradient is applied thereto by an actuation of each corresponding piezoelectric element 466, and thus define a “displaced state” of transferring element 465. In further embodiments, each transferring element 465 is made from a resilient flexible material configured to be displaced in the opposite direction (i.e., “outwards”) and to restore its original shape when said pressure or stress gradient is no longer applied thereto, and thus to define a “relaxed state” of each transferring element 465. According to some embodiments, transferring element 465 is made from a resilient flexible material so as to be displaced inwards toward the liquid composition disposed therein upon transition from the relaxed state to the displaced state. According to some embodiments, transferring element 465 is configured to displaced outward to restore its original shape upon transition from the displaced state to the relaxed state.

[0144] The terms “inwards” or “outwards”, refer to a direction or position which is closer, or away from, respectively, the perpendicular axis 401 (see Figure 7A) extending through the center of each transferring element 465.

[0145] According to some embodiments, each transferring element 465 is made of a resilient flexible material comprising an elastomeric material (e.g., elastomeric polymer), configured to provide material resiliency and sufficient flexibility to transition between the different states thereof disclosed herein. According to some embodiments, the transferring element 465 is made of a thermoplastic material selected from the group consisting of: polyamides, polyesters, polyethers, polyurethanes, polyolefins, polytetrafluoroethylenes, and combinations and copolymers thereof. Each possibility represents a different embodiment.

[0146] According to some embodiments, the transferring element 465 is made from a thermoplastic elastomer selected from the group consisting of: thermoplastic polyurethane (TPU), styrene block copolymers (TPS), Thermoplastic polyolefinelastomers (TPO), thermoplastic vulcanizates (TPV), thermoplastic copolyester (TPC), thermoplastic polyamides (TPA), and combinations thereof. Each possibility represents a different embodiment. According to some embodiments, the transferring element 465 is made from TPU.

[0147] According to some embodiments, each transferring element 465 is made from a resilient flexible material having a modulus of elasticity greater than about 0.5 GPa, optionally greater than about 1.0 GPa, or alternatively greater than about 1.5 GPa.

[0148] According to some embodiments, each transferring element 465 may be identical to each transferring element 165 or to each porous transferring element 365, as disclosed herein above.

[0149] According to some embodiments, the piezoelectric element 466 is in the form of a box directly contacting the transferring element 465 or portions thereof (e.g., lumen 464), as illustrated at Figure 7A. It is to be understood, however, that piezoelectric element 466 can be in any other suitable form, such as a sphere, cylinder, tube, coil, or any other polyhedron in the art.

[0150] According to some embodiments, each piezoelectric element 466 is electrically connected to the power source 130, and is configured to receive power therefrom, to enable the actuation thereof. According to some embodiments, each piezoelectric element 466 is in operative communication with the controller 150.

[0151] According to some embodiments, each piezoelectric element 466 is configured such that when actuated, each piezoelectric element 466 transmits vibration force or energy to each corresponding transferring element 465 along the longitudinal direction, thus causing the transferring element 465 to be displaced inwards, to the displaced state. Actuation of each piezoelectric element 466 by a voltage pulse by the power source 130 causes inwards motion of each corresponding transferring element 465, and generates an acoustic pressure or stress wave through the wall 463 of each transferring element 465, which results in longitudinal motion or displacement of the wall, thereby causing a droplet of a predetermined volume of the liquid composition to be ejected from the second end 462 of each transferring element 465. According to some embodiments, the actuation of each piezoelectric element 466 can generate a pressure wave that propagates in the liquid, and can cause displacement of the second end 462 of each corresponding transferring element 465, so as to eject a predetermined volume of the liquid composition therefrom, thus forming droplets.

[0152] According to some embodiments, it is suggested that the combination between the amplitude and frequency of each piezoelectric element 466, and the characteristics of the resilient flexible material of each corresponding transferring element 465, can define the flow rate and/or the amount of droplets (e.g., the total volume) being ejected from the second end 462 of each transferring element 465, and thus define the amount of liquid (i.e., the dose) which is being transferred therethrough, from each liquid chamber 112 into the mixing chamber 120. Advantageously, said combination enables to control the dosage from each liquid chamber 112 to be transferred into the mixing chamber 120 and to form various liquids mixtures therein, and thus to maintain the entourage effect of various cannabinoids mixtures as disclosed herein above, similarly to the utilization of fluid control mechanism 160 featuring transferring element 165 and heating element 166. Therefore, it should be understood that the utilization and purpose of piezoelectric element 466 can be similar to those of heating element 166, as disclosed herein above.

[0153] Reference is now made to Figures 8A-B, illustrating a cross sectional view and a cross sectional view in perspective, respectively, of a portion of the liquid cartridge 110 and a portion of a fluid control mechanism 560, according to some embodiments. [0154] Fluid control mechanism 560 of Figures 8A-B is similar to fluid control mechanism 460 of Figures 7A-B, and therefore share many common features as can be appreciated by the skilled in the art. Specific features or components are described below.

[0155] Thus, Figures 8A-B shows exemplary alternative implementations of some components of the fluid control mechanism. Specifically, fluid control mechanism 560 shows a circumferential piezoelectric element 566.

[0156] According to some embodiments, piezoelectric element 466 is a circumferential piezoelectric element 566 which surrounds or encompasses the transferring element 465 or portions thereof (e.g., lumen 464). In some embodiments, the circumferential piezoelectric element 566 is a cylindric or ring-shaped piezoelectric element, as illustrated at Figure 8B. It is to be understood, however, that circumferential piezoelectric element 566 can be in any other suitable form, such as a sphere, ellipsoid, box, or any other polyhedron in the art. In some embodiments, the circumferential piezoelectric element 566 is tubular and is directly coupled to the transferring element 465 it encompasses.

[0157] According to some embodiments, actuation of each circumferential piezoelectric element 566 by a voltage pulse transferred therethrough causes radially inwards motion or displacement (i.e., in the direction of the perpendicular axis 401) of the wall 463 of each corresponding transferring element 465 (or portions thereof), and thus generates an acoustic pressure or stress wave therethrough the wall thereof, which can result in axial or vertical liquid motion therewithin. According to some embodiments, each actuated circumferential piezoelectric element 566 can generate a pressure wave that propagates in the liquid along perpendicular axis 401, and can cause displacement of the second end 462 of each corresponding transferring element 465, so as to eject a predetermined volume of the liquid composition therefrom, thus forming droplets.

[0158] According to some embodiments, each circumferential piezoelectric element 566 can generate an acoustic shockwave (i.e., a uniform acoustic pressure or stress wave) which causes radially inwards motion or displacement of the wall 463 of each corresponding transferring element 465. The radially inwards displacement of the wall 463 of transferring element 465 may affect the liquid disposed therein, such as by reducing the capillary and/or viscous forces residing therewithin. This can cause the formation of droplets having predetermined volumes which are ejected from the second end 462 of each transferring element 465 into the mixing chamber 120.

[0159] According to some embodiments, it is suggested that the combination between the amplitude and frequency of the acoustic shockwave generated by each circumferential piezoelectric element 566, and the characteristics of the resilient flexible material of each corresponding transferring element 465, can define the flow rate and/or the amount of droplets (e.g., the total volume) being ejected from the second end 462 of each corresponding transferring element 465, and thus define the amount of liquid (i.e., the dose) which is being transferred therethrough, from each liquid chamber 112 into the mixing chamber 120. Advantageously, said combination enables to control the dosage from each liquid chamber 112 to be transferred into the mixing chamber 120 and to form various liquids mixtures therein, and thus to maintain the entourage effect of various cannabinoids mixtures as disclosed herein above.

[0160] Reference is now made to Figures 9A-10. Figures 9A-B illustrates views in perspective of a liquid cartridge 610 and a portion thereof, respectively, according to some embodiments. Figures 9C-D illustrates cross sections of a liquid chamber 612, according to some embodiments. Figure 10 illustrates a cross sectional side view of a vaporization device 600 comprising the fluid control mechanism 660, according to some embodiments.

[0161] Fluid control mechanism 660 and vaporization device 600 of Figures 9 A- 10 are similar to fluid control mechanism 160 and vaporization device 100 of Figures 1-3, respectively, and therefore share many common features as can be appreciated by the skilled in the art. Specific features or components are described below.

[0162] Thus, Figures 9A-10 shows exemplary alternative implementations of some components of the fluid control mechanism and the liquid cartridge. Specifically, vaporization device 600 comprises a liquid cartridge 610 showing a different configuration of each liquid chamber 612. [0163] According to some embodiments, there is provided a vaporization device 600 comprising a housing 604 comprising at least one of: a liquid cartridge chamber 616 optionally comprising a liquid cartridge 610 comprising a plurality of liquid chambers 612 disposed therein, a mixing chamber 620, a power source chamber 638 optionally comprising a power source 630 disposed therein, a mouthpiece 640 comprising at least a portion of at least one fluid path 642, a controller 650, a user interaction portion 636, a sensor 632, a power source controller 652, a fluid control mechanism, and combinations thereof. Each possibility represents a different embodiment. It should be understood that the housing 604, mixing chamber 620, power source 630, mouthpiece 640, fluid path 642, controller 650, user interaction portion 636, sensor 632, and power source controller 652 of device 600 can be similar or identical to the housing 104, mixing chamber 120, power source 130, mouthpiece 140, fluid path 142, controller 150, user interaction portion 136, sensor 132, and power source controller 152 of device 100, respectively, and therefore have the same or similar utilization and/or purposes.

[0164] According to some embodiments, the liquid cartridge 610 comprises a cartridge housing 611 accommodating therein a plurality of liquid chambers 612 (see Figure 9A).

[0165] According to some embodiments, the liquid cartridge 610 comprises a cartridge electrical connector 615 configured to receive power from the power source 630, optionally via the power source controller 652. According to some embodiments, the liquid cartridge 610 comprises a power management component 621 (optionally mounted on a PCB), configured to receive power from the cartridge electrical connector 615 and to transfer it to each liquid chamber 612. According to some embodiments, the power management component 621 is configured to provide structural support to the mixing chamber 620 which is coupled thereto and/or mounted thereon. In further embodiments, each liquid chamber 612 comprises a power contact 626 configured to receive power from the power management component 621 and to transfer it to the inner electrical components disposed therein (e.g., a corresponding flow inducing element 663).

[0166] According to some embodiments, the cartridge housing 611 is detachably attached from the housing 604, or specifically from the liquid cartridge chamber 616, via various attachment means, as disclosed herein above. In further such embodiments, the liquid cartridge 610 could be refilled or replaced.

[0167] According to some embodiments, the cartridge housing 611 comprises a plurality of fluid intake apertures 625 configured to facilitate fluid communication (i.e., air flow) between an external environment of the device 600 and each liquid chamber 612. Upon user inhalation, air from the external environment can flow into the cartridge housing 611 via the plurality of fluid intake apertures 625, and into each liquid chamber 612 via a corresponding liquid chamber inlet 624 leading into a fluid inflow path 643A disposed within each liquid chamber 612. According to some embodiments, each fluid inflow path 643 A is in fluid communication or is directly connected to each corresponding liquid chamber inlet 624. According to some embodiments, each liquid chamber inlet 624 is in fluid communication with one or more of the fluid intake apertures 625 of the cartridge housing 611.

[0168] According to some embodiments, each liquid chamber 612 comprises a liquid chamber inlet 624 and a liquid chamber outlet 670, wherein said inlet 624 is in fluid communication with said outlet 670. In further embodiments, each inlet 624 and corresponding outlet 670 are in the form of apertures or openings, extending through different sections or portions of a housing of each liquid chamber 612.

[0169] According to some embodiments, the liquid cartridge 610 comprises the mixing chamber 620 disposed therein, wherein said mixing chamber 620 is fluidly coupled to each liquid chamber 612. In further embodiments, the mixing chamber 620 is fluidly coupled to each fluid outflow path 643C via the corresponding liquid chamber outlet 670 of each corresponding liquid chamber 612.

[0170] According to some embodiments, the mixing chamber 620 comprises a mixing chamber exit 641 configured to enable fluid (e.g., vapor and/or aerosol) flow therefrom and into at least a portion of the at least one fluid path 642 along a flow direction 601 (see Figure 9B). In further embodiments, the mixing chamber exit 641 is configured to enable fluid communication between the mixing chamber 620 and the fluid path 642. [0171] According to some embodiments, the mixing chamber 620 further comprises at least one heating element 669 disposed therein (see Figure 9B), which can be identical to heating element 169 as disclosed herein above and is used for the same purpose.

[0172] According to some embodiments, the fluid control mechanism disposed within the vaporization device 600 is a fluid control mechanism 660.

[0173] According to some embodiments, each liquid chamber 612 comprises a liquid chamber housing 613 accommodating therein the inner components of each liquid chamber 612. In further embodiments, each liquid chamber housing 613 is permanently coupled to the cartridge housing 611 or is detachably attached therefrom. According to some embodiments, each liquid chamber housing 613 defines an inner surface 623, wherein said inner surface 623 defines a chamber inner space 622 configured to hold or contain a liquid composition 113 disposed therein.

[0174] According to some embodiments, the chamber inner space 622 of each liquid chamber 612 can be sealed by a sealing element 627, optionally configured to be removed for enabling to refill each chamber inner space 622 with a new liquid composition 113. The sealing element 627 can comprise a sealing protrusion configured to be detachably attached from a corresponding recesses extending through at least a portion of the liquid chamber housing 613.

[0175] According to some embodiments, the fluid control mechanism 660 comprises a plurality of transferring elements 665 and a plurality of corresponding flow inducing elements 663, wherein the liquid cartridge 610 comprises a plurality of liquid chambers 612, and wherein each transferring element 665 is fluidly coupled to a corresponding liquid chamber 612 at one end or surface thereof and to the mixing chamber 620 in the other end or surface thereof.

[0176] According to some embodiments, each liquid chamber 612 comprises a corresponding transferring element 665 disposed therein, such that the liquid chamber 612 defines the chamber inner space 622 between the inner surface 623 and the transferring element 665, wherein the chamber inner space 622 is configured to contain a liquid composition disposed therein. In some embodiments, the chamber inner space 622 of each liquid chamber 612 and the liquid composition 113 disposed therein surrounds or encompasses the transferring element 665.

[0177] According to some embodiments, each transferring element 665 extends radially inwards from an outer first surface 661 towards an inner second surface 662, and defines a middle portion 664 extending therebetween, wherein the first surface 661 is in fluid communication with the chamber inner space 622 of the liquid chamber 612, and the second surface 662 thereof is in fluid communication with the mixing chamber 620 and with the corresponding liquid chamber inlet 624. According to some embodiments, the chamber inner space 622 is in fluid communication with the transferring element 665, and wherein the transferring element 665 is configured to allow liquid flow from the chamber inner space 622, therethrough and toward the liquid chamber outlet 670. According to some embodiments, a portion of the transferring element 665 is coupled to the liquid chamber outlet 670, to a portion of the inner surface 623, or both.

[0178] The term "radially inwards" as used herein, refers to a direction or position which is closer to a perpendicular axis 602, extending through the center of each transferring element 665 (see Figure 9C).

[0179] In some embodiments, the middle portion 664 of each transferring element 665 is directly or indirectly connected to at least one corresponding flow inducing element 663. In further embodiments, each flow inducing element 663 is embedded or integrated within the middle portion 664 of each corresponding transferring element 665.

[0180] In some embodiments, each flow inducing element 663 is a heating element 666. In some embodiments, each heating element 666 is a heating coil, which is embedded within the middle portion 664 of each corresponding transferring element 665, as illustrated at Figure 9C. In other embodiment, each heating element 666 is a heating coil which is connected to the first surface 661 and/or to the second surface 662 of each transferring element 665 (not shown).

[0181] According to some embodiments, each transferring element 665 defines a fluid inner path 643B extending therethrough (optionally at the center thereof), so that the second surface 662 thereof is circumferentially surrounding the fluid inner path 643B. In some embodiments, the second surface 662 of each transferring element 665 is in fluid communication with each corresponding fluid inner path 643B. In some embodiments, each fluid inner path 643B extends through each transferring element 665 along a perpendicular axis 602 extending through the center of each transferring element 665. According to some embodiments, prior to the activation of the fluid control mechanism 660, the fluid inner path 643B is hollow or empty.

[0182] In some embodiments, each fluid inner path 643B is in fluid communication (or is in direct contact with) with the fluid inflow path 643A. In some embodiments, each fluid inner path 643B is in fluid communication (or is in direct contact with) with a corresponding fluid outflow path 643C, wherein each fluid outflow path 643C is connected to the mixing chamber 620 via the liquid chamber outlet 670. In further embodiments, each fluid inflow path 643A, fluid inner path 643B, and fluid outflow path 643C of each corresponding liquid chamber 612 together form an air flow path that enables air passage from the external environment of the device 600 and into the center of each transferring element 665 disposed within each corresponding liquid chambers 612 and into the mixing chamber 620. In some embodiments, each fluid inflow path 643A and/or corresponding fluid outflow path 643C can be in the form or shape of a tube, channel, conduit, pipe, or any other suitable form which enables fluid flow therethrough.

[0183] In some embodiments, the second surface 662 of each transferring element 665 is in fluid communication with the mixing chamber 620 via each corresponding fluid inner path 643B and optionally fluid outflow path 643C. In some embodiments, the fluid inner path 643B is extending through the transferring element 665 and is in fluid communication with the mixing chamber 620 via the liquid chamber outlet 670, wherein the fluid inner path 643B is further in fluid communication with the liquid chamber inlet 624.

[0184] According to some embodiments, each transferring element 665 is shaped as a cylinder circumferentially surrounding the fluid inner path 643B. According to some embodiments, each transferring element 665 is porous and is made from a porous material comprising interconnected pores, having an interconnected porous inner volume (extending between the outer first surface 661 and the inner second surface 662) and is selected from the range of about 1 nanoliter - 100 microliters. In further embodiments, the volume is selected from the range of about 1 - 1000 nanoliters. In still further embodiments, the volume is selected from the range of about 10 - 500 nanoliters. In yet still further embodiments, the volume is selected from the range of about 20 - 200 nanoliters.

[0185] According to some embodiments, each transferring element 665 is in the form of a porous cylinder circumferentially surrounding the fluid inner path 643B. According to some embodiments, each transferring element 665 is made from a material which enables to transfer heat therethrough, such as for example a metal or metal alloy, a polymer or polymer blend, ceramics, and combinations thereof.

[0186] According to some embodiments, the first surface 661 of each transferring element 665 is in direct contact with the liquid composition 113 disposed within the chamber inner space 622 of the liquid chamber 612 (not shown).

[0187] According to some alternative embodiments, each transferring element 665 further comprises a circumferential layer 667 configured to wick portions of the liquid composition 113 disposed within the chamber inner space 622 of each liquid chamber 612, and to enable fluid communication therethrough towards the first surface 661 thereof. According to some embodiments, the first surface 661 of each transferring element 665 is at least partially surrounded by a wicking circumferential layer 667 configured to enable fluid communication therethrough towards the first surface 661. The wicking circumferential layer 667 can enable to draw/wick portions of the liquid composition 113 disposed within the chamber inner space 622 of each liquid chamber 612 therethrough and towards the transferring element 665, and optionally to prevent leakage therebetween. The wicking circumferential wick layer 667 can be made from a porous material. The wicking circumferential wick layer 667 can be made from cotton, fiberglass, other suitable materials, and combination thereof. Each possibility represents a different embodiment.

[0188] According to some embodiments, each transferring element 665 further comprises a circumferential perforated shield 668 configured to enable fluid communication therethrough towards the first surface 661 thereof. According to some embodiments, the wicking circumferential layer 667 is at least partially surrounded by a circumferential perforated shield 668 comprising a plurality of apertures 669 configured to enable fluid communication therethrough (see Figure 9D). The circumferential perforated shield 668 can comprise at least one insulating material or layer (e.g., similar to insulating layer 114) configured to prevent or reduce external thermal affects and maintain a stable temperature range of the liquid composition(s) disposed within the liquid chamber 612. Advantageously, the circumferential perforated shield 668 can enable to provide structural integrity and support to each transferring element 665 and optionally to provide thermal isolation thereto. The circumferential perforated shield 668 can be made from a metal or metal alloy (e.g., stainless steel), a polymer or polymer blend, and combinations thereof. Each possibility represents a different embodiment.

[0189] According to some embodiments, one or more portions of the circumferential perforated shield 668 are coupled to one or more portions of the inner surface 623 of the liquid chamber housing 613.

[0190] According to some embodiments, the first surface 661 of each transferring element 665 is in fluid communication with the liquid composition 113 disposed within the chamber inner space 622 of each liquid chamber 612, via each circumferential layer 667 and circumferential perforated shield 668. Advantageously, in some embodiments, the combination between the circumferential perforated shield 668 surrounding the circumferential layer 667 surrounding the first surface 661 of each transferring element 665, enables to provide structural integrity and support to each transferring element 665. Furthermore, said combination disclosed herein above further provides thermal isolation and prevents leakage, thus allowing an enhanced fluid communication and wicking capabilities between the liquid composition 113 disposed within the chamber inner space 622 of each liquid chamber 612 and each corresponding transferring element 665.

[0191] According to some embodiments, portions of the liquid composition 113 disposed within the chamber inner space 622 of each liquid chamber 612 can flow (or be wicked by capillary action) through the plurality of apertures 669 of the circumferential perforated shield 668, through the circumferential layer 667, and towards the first surface 661 of the porous transferring element 665. The actuation of each heating element 666 can expedite the wicking as disclosed herein above. [0192] According to some embodiments, each heating element 666, which is embedded within the middle portion 664 or optionally connected to the first surface 661 and/or to the second surface 662 of each corresponding transferring element 665, is configured to produce thermal energy and to apply or transfer at least a portion of said thermal energy (e.g., heat) to the liquid composition disposed within or transferring through each corresponding porous transferring element 665 or portions thereof, in order to enable the evaporation thereof. In some embodiments, the amount and/or rate of thermal energy applied by each heating element 666 is identical to that of each heating element 166 as disclosed above.

[0193] According to some embodiments, it is suggested that the combination between the interconnected porous inner volume of each porous transferring element 665 and the amount of heating energy which is being transferred from each corresponding heating element 666 thereto, can define the amount of vapor (i.e., the dose) which is being transferred therethrough, from each corresponding liquid chamber 612 into the mixing chamber 120. Advantageously, said combination enables to control the dosage from each liquid chamber 612 to be transferred into the mixing chamber 620 and to form various vapors mixtures therein, and thus to maintain the entourage effect of various cannabinoids mixtures as disclosed herein above, similarly to the utilization of fluid control mechanism 160 featuring transferring element 165. Therefore, it should be understood that the utilization and purpose of porous transferring element 665 are identical or similar to those of transferring element 165, as disclosed herein above.

[0194] According to some embodiments, activation of the fluid control mechanism 660 comprises the controller 650 sensing the inhalation by the user (via a sensor 632) and/or receives the user’s input and as a result activates the plurality of heating elements 666. The power source 630 supplies a pulse of energy to each heating element 666 to heat each middle portion 664 of each corresponding transferring element 665. The liquid disposed within each chamber inner space 622 of each liquid chamber 612 is wicked towards the first surface 661 of each corresponding porous transferring element 665, optionally via the plurality of apertures 669 of the circumferential perforated shield 668 and through the circumferential layer 667. The interconnected porous inner structure of each porous transferring element 665 allows liquid transfer therethrough, from the first surface 661 towards the middle portion 664 thereof in the direction of the perpendicular axis 602. Then, the liquid is vaporized by the heating element 666 embedded within the middle portion 664 of each transferring element 665, to create a heated vapor therein, which is transferred or flows/evaporates towards the second surface 662 thereof in the direction of the perpendicular axis 602, and then into the fluid inner path 643B (see Figure 9C).

[0195] According to some embodiments, upon the activation of the fluid control mechanism and the inhalation by the user, air from the external environment flows into the device 600 via the plurality of fluid intake apertures 625 of the liquid cartridge 610, and into each liquid chamber 612 via each corresponding liquid chamber inlet 624 leading into each fluid inflow path 643 A disposed within each liquid chamber 612. The air from each fluid inflow path 643 A flows into each corresponding fluid inner path 643B along the direction of the perpendicular axis 602, and is then mixed with the heated vapors disposed therein. The mixture formed within each fluid inner path 643B flows (or evaporates) along each corresponding fluid outflow path 643C via each liquid chamber outlet 670, towards the mixing chamber 620 along the flow direction 601. In the mixing chamber 620, the vapors from each liquid chamber 612 condenses to form an inhalable aerosol mixture, which is carried towards the mouthpiece 640 and into the mouth of a user via the at least one fluid path 642. At the same time, the liquid being vaporized is replaced by further liquid moving towards the second surface 662 of each transferring element 665 by capillary action.

[0196] Thus, in some embodiments, the vaporization devices of the present invention (e.g., vaporization device 600) can be used for providing customized mixtures of aerosols for inhalation by a user, wherein said customized mixtures can have various therapeutic effects used for various forms of applications, similarly as disclosed herein above, in the context of device 100.

[0197] Reference is now made to Figures 11A-B, illustrating cross sectional views of a liquid chamber 712 and a device 600 comprising a fluid control mechanism 760, respectively, according to some embodiments. [0198] Fluid control mechanism 760 of Figures 11A-B is similar to fluid control mechanism 660 of Figures 9A-10, and therefore share many common features as can be appreciated by the skilled in the art. Specific features or components are described below.

[0199] Thus, Figures 11A-B shows exemplary alternative implementations of some components of the fluid control mechanism. Specifically, fluid control mechanism 760 includes a plurality of transferring elements 765 in the form of microchannels.

[0200] According to some embodiments, each liquid chamber 612 is a liquid chamber 712. According to some embodiments, the liquid cartridge 610 comprises a plurality of liquid chambers 712 disposed therein. According to some embodiments, the cartridge housing 611 accommodates therein a plurality of liquid chambers 712. According to some embodiments, the cartridge electrical connector 615 is configured to receive power from the power source 630 and to transfer it to each liquid chamber 712.

[0201] According to some embodiments, the mixing chamber 620 of the liquid cartridge 610 is fluidly coupled to each liquid chamber 712. In further embodiments, the mixing chamber 620 is fluidly coupled to each fluid outflow path 743C of each corresponding liquid chamber 712. According to some embodiments, the mixing chamber 620 comprises at least one heating element 669 as disclosed above.

[0202] According to some embodiments, the cartridge housing 611 comprises at least one fluid intake aperture 625 configured to facilitate fluid communication (i.e., air flow) between an external environment of the device 600 and the mixing chamber 620 via at least one fluid inflow path 743 A. According to some embodiments, the cartridge housing 611 comprises a plurality of fluid intake apertures 625 configured to facilitate fluid communication (i.e., air flow) between an external environment of the device 600 and the mixing chamber 620. Upon user inhalation, air from the external environment can flow into the cartridge housing 611 via the plurality of fluid intake apertures 625, and into the mixing chamber 620 via a corresponding plurality of fluid inflow paths 743 A disposed within the cartridge housing 611.

[0203] According to some embodiments, each fluid inflow path 743A is in fluid communication (or is directly connected) to each corresponding fluid intake aperture 625 at one end thereof, and to the mixing chamber 620 in the other end thereof (see Figure 11B). According to other embodiments, each fluid inflow path 743A is in fluid communication (or is directly connected) to each corresponding fluid intake aperture 625 at one end thereof, and to a corresponding liquid chamber outlet 770 of each corresponding liquid chamber 712 in the other end thereof (not shown).

[0204] According to some embodiments, the fluid control mechanism disposed within the vaporization device 600 is a fluid control mechanism 760.

[0205] According to some embodiments, each liquid chamber 712 comprises a liquid chamber housing 713 accommodating therein the inner components of each liquid chamber 712. In further embodiments, each liquid chamber housing 713 is coupled to the cartridge housing 611. According to some embodiments, each liquid chamber housing 713 defines an inner surface 723, wherein said inner surface 723 defines a chamber inner space 722 configured to hold or contain a liquid composition 113 disposed therein. The chamber inner space 722 of each liquid chamber 712 can be sealed by a sealing element 727, optionally configured to be removed for enabling to refill each chamber inner space 722 with a new liquid composition 113.

[0206] According to some embodiments, the fluid control mechanism 760 comprises a plurality of transferring elements 765 and a plurality of corresponding flow inducing elements 763, wherein the liquid cartridge 610 comprises a plurality of liquid chambers 712, and wherein each transferring element 765 is fluidly coupled to a corresponding liquid chamber 712 at one end or surface thereof and to the mixing chamber 620 in the other end or surface thereof.

[0207] According to some embodiments, each liquid chamber 712 comprises at least one transferring element 765 disposed therein, such that the liquid chamber 712 defines the chamber inner space 722 between the inner surface 723 and the at least one transferring element 765, wherein the chamber inner space 722 is configured to contain a liquid composition disposed therein. In some embodiments, the chamber inner space 722 of each liquid chamber 712 and the liquid composition 113 disposed therein surrounds or encompasses the at least one transferring element 765. [0208] According to some embodiments, each transferring element 765 extends from a first end 761 towards a second end 762 along a perpendicular axis 702 (extending through the center of each transferring element 765), and defines a lumen 764 extending therebetween. In some embodiments, the first end 761 of each transferring element 765 is in fluid communication with the chamber inner space 722 of the liquid chamber 712. In some embodiments, the second end 762 of each transferring element 765 is in fluid communication with the mixing chamber 620. In some embodiments, the first end 761 of each transferring element 765 is in direct contact with the liquid composition 113 disposed within the chamber inner space 722 of the liquid chamber 712.

[0209] In some embodiments, the lumen 764 of each transferring element 765 is directly or indirectly connected to at least one corresponding flow inducing element 763. In some embodiments, each flow inducing element 763 is embedded within or around the lumen 764 of each corresponding transferring element 765. In some embodiments, each flow inducing element 763 is surrounding or enveloping an external surface of the lumen 764 of each corresponding transferring element 765.

[0210] In some embodiments, each flow inducing element 763 is a heating element 766. In further embodiments, each heating element 766 is shaped as a heating coil which is surrounding the lumen 764 of each corresponding transferring element 765, as illustrated at Figure 11A.

[0211] In some embodiments, each liquid chamber 712 comprises a plurality of transferring elements 765 disposed therein, such that the first end 761 of each transferring element 765 is in fluid communication with the chamber inner space 722 and the second end 762 of each transferring element 765 is in fluid communication with the mixing chamber 620 (not shown). In further such embodiments, each transferring element 765 of the plurality of transferring elements 765 disposed within each liquid chamber 712 is coupled to at least one corresponding heating element 766, wherein said heating element 766 is optionally a heating coil as disclosed above. In still further such embodiments, each liquid chamber 712 comprises a plurality of heating elements 766 disposed therein. [0212] According to some embodiments, each transferring element 765 is in the form of an elongated tube or channel. In some embodiments, each transferring element 765 is a microchannel. In some embodiments, each transferring element 765 is a tubular microchannel. In some embodiments, each transferring element 765 is similar or identical to each transferring element 165 as disclosed above. According to some embodiments, each transferring element 765 has a volume selected from the range of about 1 nanoliter - 100 microliters. In further embodiments, the volume of each transferring element 765 is selected from the range of about 20-200 nanoliters.

[0213] According to some embodiments, each liquid chamber 712 or corresponding transferring element 765 further comprises a circumferential insulating layer 729, configured to prevent or reduce the amount of thermal energy generated by each heating element 766 and directed towards the liquid disposed within the liquid chamber 712, prevent or reduce other external thermal affects, and maintain a stable temperature range of the liquid composition(s) disposed within the liquid chamber 712. The circumferential insulating layer 729 can comprise at least one insulating material, similar or identical to insulating layer 114 as disclosed above.

[0214] According to some embodiments, each heating element 766 is at least partially surrounded by each corresponding circumferential insulating layer 729. According to some embodiments, each transferring element 765 or a portion thereof is surrounded by each corresponding circumferential insulating layer 729. According to some embodiments, each circumferential insulating layer 729 is at least partially encompassing or enveloping each corresponding heating element 766 or a portion thereof.

[0215] According to some embodiments, each liquid chamber 712 or transferring element 765 further comprises a corresponding support structure element 767 which is at least partially circumferentially encompassing or enveloping each corresponding transferring element 765 or a portion thereof and/or the corresponding circumferential insulating layer 729. According to some embodiments, each support structure element 767 is configured to support the structure and integrity of its corresponding transferring element 765, and optionally each corresponding circumferential insulating layer 729. The support structure element 767 can be made from a metal or metal alloy (e.g., stainless steel), ceramics, a polymer or polymer blend, and combinations thereof. Each possibility represent a different embodiment.

[0216] According to some embodiments, each support structure element 767 is directly encompassing or enveloping each corresponding transferring element 765 or a portion thereof (not shown). According to other embodiments, each support structure element 767 is directly encompassing or enveloping each corresponding circumferential insulating layer 729 and each corresponding transferring element 765 or a portion thereof (see Figure 11A).

[0217] According to some embodiments, each support structure element 767 is integrally formed with each corresponding circumferential insulating layer 729. According to some embodiments, each circumferential insulating layer 729 is embedded within each support structure element 767. According to other embodiments, each support structure element 767 and each corresponding circumferential insulating layer 729 are separate components detachably attached to each other.

[0218] According to some embodiments, each liquid chamber 712 or transferring element 765 further comprises a circumferential perforated shield 768 configured to enable fluid communication therethrough towards the first end 761 thereof. According to some embodiments, each support structure element 767 is at least partially surrounded and/or supported by a circumferential perforated shield 768 comprising a plurality of apertures 769 configured to enable fluid communication therethrough (see Figure 11A). Each circumferential perforated shield 768 can be made from materials similar or identical to each circumferential perforated shield 668 as disclosed above. According to some embodiments, one or more portions of the circumferential perforated shield 768 are coupled to one or more portions of the inner surface 723 of the liquid chamber housing 713.

[0219] Advantageously, the combination between each circumferential perforated shield 768 surrounding each support structure element 767 and each circumferential insulating layer 729, both surrounding each corresponding transferring element 765, can enable to provide structural integrity and support to each transferring element 765. Furthermore, said combination disclosed herein above further provides thermal isolation and prevents leakage, thus allowing an enhanced fluid communication and wicking capabilities between the liquid composition 113 disposed within the chamber inner space 722 of each liquid chamber 712 and each corresponding transferring element 765.

[0220] According to some embodiments, each circumferential perforated shield 768 comprises a first portion 768A defining a shield inner space 728 configured to enable fluid communication therethrough via the plurality of apertures 669; and a second portion 768B configured to support and be attached to each support structure element 767 as disclosed above. In some embodiments, the first end 761 of each transferring element 765 is in direct contact with the liquid composition 113 disposed within the chamber inner space 722 of the liquid chamber 712 via the shield inner space 728 defined by the first portion 768A of each circumferential perforated shield 768.

[0221] In some embodiments, the second end 762 of each transferring element 765 is in fluid communication with the mixing chamber 620 via a fluid outflow path 743C extending through a corresponding liquid chamber outlet 770 of each corresponding liquid chamber 712. In some embodiments, the mixing chamber 620 is fluidly coupled to each fluid outflow path 743C via the corresponding liquid chamber outlet 770 of each corresponding liquid chamber 712. According to some embodiments, the second end 762 of the transferring element 765 is coupled to the liquid chamber outlet 770, to a portion of the inner surface 723, or to both.

[0222] According to some embodiments, portions of the liquid composition 113 disposed within the chamber inner space 722 of each liquid chamber 712 can flow and/or be wicked through the plurality of apertures 769 of the circumferential perforated shield 768 into the shield inner space 728 defined by the first portion 768A thereof, and into the transferring element 765 by capillary action via the first end 761 thereof. The actuation of each heating element 766 can optionally expedite the wicking as disclosed herein above.

[0223] According to some embodiments, each heating element 766 is shaped as a heating coil which is surrounding at least a portion of the lumen 764 of each corresponding transferring element 765 and is configured to produce thermal energy, and to apply or transfer at least a portion of said thermal energy (e.g., heat) to the liquid composition disposed within or transferring through each corresponding transferring element 765 or portions thereof, in order to enable the heating or evaporation thereof. In some embodiments, the amount and/or rate of the thermal energy applied by each heating element 766 is identical to that of each heating element 166 as disclosed above.

[0224] According to some embodiments, it is suggested that the combination between the volume of each transferring element 765 and the amount of thermal energy applied from each corresponding at least one heating element 766 thereto, can define the amount of liquid or vapor (i.e., “dose”) which is being transferred therethrough, from each corresponding liquid chamber 712 into the mixing chamber 620. Advantageously, said combination enables to control the dosage from each liquid chamber 712 which is transferred into the mixing chamber 620 and to form various liquids or vapors mixtures therein, and thus to maintain the entourage effect of various cannabinoids mixtures as disclosed herein above, similarly to the utilization of fluid control mechanism 160 featuring transferring element 165. Therefore, it should be understood that the utilization and purpose of the microchannel transferring element 765 are identical or similar to those of transferring element 165, as disclosed herein above.

[0225] According to some embodiments, activation of the fluid control mechanism 760 comprises the controller 650 sensing the inhalation by the user (via a sensor 632) and/or receives the user’s input and as a result activates the plurality of heating elements 766. The power source 630 supplies a pulse of energy to each heating element 766 to heat at least a portion of each lumen 764 of each corresponding transferring element 765. The liquid disposed within each chamber inner space 722 of each liquid chamber 712 is wicked towards the first end 761 of each corresponding microchannel transferring element 765, optionally via the plurality of apertures 769 of the circumferential perforated shield 768 and via the shield inner space 728 defined by the first portion 768A thereof.

[0226] Then, the liquid within each microchannel transferring element 765 is heated or vaporized by the heating element 766 surrounding at least a portion of each lumen 764 thereof, to create a heated liquid or heated vapor therein, respectively, which is transferred or flows towards the second end 762 thereof in the direction of the flow arrow 701, and then into the mixing chamber 620 along each fluid outflow path 743C via the corresponding liquid chamber outlet 770 of each corresponding liquid chamber 712. At the same time, the liquid being heated or vaporized is replaced by further liquid moving towards the first end 761 of each transferring element 765 by capillary action.

[0227] According to some embodiments, the heated vapor of each transferring element 765 is transferred into the mixing chamber 620, to from a mixture of vapors, and then optionally mixed with air flowing thereto from the at least one fluid path 642 and/or from the at least one fluid intake aperture 625 of the device 600. In the mixing chamber 620, the vapor condenses to form an inhalable aerosol, which is carried towards the mouthpiece 640 and into the mouth of a user via the at least one fluid path 642.

[0228] According to alternative embodiments, the heated liquid at each transferring element 765 is transferred into the mixing chamber 620, to from a mixture of liquids therein. The least one heating element 669 disposed within the mixing chamber 620 can generate the evaporation thereof to create heated vapors therein, which are then mixed with air flowing thereto, and condenses to form inhalable aerosols, which is then carried towards the mouthpiece 640 and into the mouth of a user via the at least one fluid path 642. The air flowing into the mixing chamber 620 can flow from the at least one fluid path 642 and/or from the at least one fluid intake aperture 625 of the device 100.

[0229] Reference is now made to Figure 12, illustrating a cross sectional side view of a liquid chamber 712 comprising a fluid control mechanism 860, according to some embodiments.

[0230] Fluid control mechanism 860 of Figure 12 is similar to fluid control mechanism 760 of Figures 11A-B, and therefore share many common features as can be appreciated by the skilled in the art. Specific features or components are described below.

[0231] Thus, Figure 12 shows exemplary alternative implementations of some components of the fluid control mechanism. Specifically, fluid control mechanism 860 includes a plurality of piezoelectric elements.

[0232] According to some embodiments, the fluid control mechanism disposed within the vaporization device 600 is a fluid control mechanism 860. [0233] According to some embodiments, the fluid control mechanism 860 comprises a plurality of transferring elements 765 and a plurality of corresponding flow inducing elements 763, wherein the liquid cartridge 610 comprises a plurality of liquid chambers 712, and wherein each transferring element 765 is fluidly coupled to a corresponding liquid chamber 712 at one end or surface thereof and to the mixing chamber 620 in the other end or surface thereof.

[0234] According to some embodiments, each liquid chamber 712 comprises at least one transferring element 765 disposed therein, such that the liquid chamber 712 defines the chamber inner space 722 between the inner surface 723 and the at least one transferring element 765, wherein the chamber inner space 722 is configured to contain a liquid composition disposed therein. In some embodiments, the chamber inner space 722 of each liquid chamber 712 and the liquid composition 113 disposed therein surrounds or encompasses the transferring element 765.

[0235] According to some embodiments, each transferring element 765 extends from a first end 761 towards a second end 762 along a perpendicular axis 702 (extending through the center of each transferring element 765), and defines a lumen 764 extending therebetween. In some embodiments, the lumen 764 of each transferring element 765 is directly or indirectly connected to at least one corresponding flow inducing element 763. In some embodiments, each flow inducing element 763 is embedded within or around the lumen 764 of each corresponding transferring element 765. In some embodiments, each flow inducing element 763 is surrounding or enveloping an external surface of the lumen 764 of each corresponding transferring element 765.

[0236] In some embodiments, each flow inducing element 763 is a piezoelectric element 866. In some embodiments, each piezoelectric element 866 is a circumferential piezoelectric element 866 which surrounds or encompasses each corresponding transferring element 765 or portions thereof (e.g., lumen 764), as illustrated at Figure 12. In some embodiments, the circumferential piezoelectric element 866 is a cylindric or ring-shaped piezoelectric element, as illustrated at Figure 12. It is to be understood, however, that circumferential piezoelectric element 866 can be in any other suitable form, such as a sphere, ellipsoid, box, or any other polyhedron in the art. In some embodiments, the circumferential piezoelectric element 866 is tubular and is directly coupled to the transferring element 765 it encompasses.

[0237] In some embodiments, each liquid chamber 712 comprises a plurality of transferring elements 765 and a plurality of piezoelectric elements 866 disposed therein, wherein each transferring element 765 of the plurality of transferring elements 765 is directly or indirectly connected to at least one corresponding piezoelectric element 866 of the plurality of piezoelectric elements 866 (not shown).

[0238] According to some embodiments, each transferring element 765 is in the form of an elongated fluid conduit, tube or channel. According to some embodiments, each transferring element 765 is made from a resilient flexible material configured to enable the displacement thereof along the longitudinal direction towards the liquid composition disposed therein (i.e., “inwards”), when a pressure or stress gradient is applied thereto by an actuation of each corresponding piezoelectric element 866, wherein each transferring element 765 is similar or identical to each transferring element 465 as disclosed herein above.

[0239] According to some embodiments, each piezoelectric element 866 is at least partially surrounded by a corresponding circumferential layer 829. According to some embodiments, each transferring element 765 or a portion thereof is surrounded by a corresponding circumferential layer 829. According to some embodiments, each circumferential layer 829 is configured to structurally support each piezoelectric element 866 and/or each transferring element 765 or a portion thereof. According to some embodiments, each circumferential layer 829 is made from a vibration absorbing material (e.g., elastic polymers, porous materials, etc.) configured to absorb vibration energy induced by the piezoelectric element 866, so that the vibrating piezoelectric element 866 won't affect other elements disposed within the liquid chamber 712.

[0240] According to some embodiments, each support structure element 767 is at least partially circumferentially encompassing or enveloping each corresponding transferring element 765 or a portion thereof and/or the corresponding circumferential layer 829 or a portion thereof. According to some embodiments, each support structure element 767 is configured to support the structure and integrity of its corresponding transferring element 765, and optionally each corresponding circumferential layer 829.

[0241] According to some embodiments, activation of the fluid control mechanism 860 comprises the controller 650 sensing the inhalation by the user (via a sensor 632) and/or receives the user’s input and as a result activates the plurality of piezoelectric elements 866. The liquid disposed within each chamber inner space 722 of each liquid chamber 712 is wicked towards the first end 761 of each corresponding transferring element 765, optionally via the plurality of apertures 769 of the circumferential perforated shield 768 and via the shield inner space 728 defined by the first portion 768A thereof. Then, the liquid within each transferring element 765 is affected by the corresponding actuated piezoelectric element 866, wherein each piezoelectric element 866 transmits vibration force or energy to each corresponding transferring element 765, similarly as disclosed herein above in the context of transferring element 465.

[0242] According to some embodiments, the power source 630 supplies a voltage pulse transferred to each piezoelectric element 866, which causes radially inwards motion or displacement (i.e., in the direction of the perpendicular axis 702) of the wall of each corresponding transferring element 765 (or portions thereof), and thus generates an acoustic pressure or stress wave therethrough the wall thereof, which can result in axial or vertical liquid motion therewithin. According to some embodiments, each actuated piezoelectric element 866 can generate a pressure wave that propagates in the liquid along perpendicular axis 702, and can cause displacement of the second end 762 of each corresponding transferring element 765, so as to eject a predetermined volume of the liquid composition therefrom (thus forming droplets) into the mixing chamber 620, along each fluid outflow path 743C via the corresponding liquid chamber outlet 770, of each corresponding liquid chamber 712.

[0243] According to some embodiments, the liquid from each transferring element 765 is transferred into the mixing chamber 620 as disclosed herein above, to from a mixture of liquids therein. The least one heating element 669 disposed within the mixing chamber 620 can generate the evaporation thereof to create heated vapors therein, which are then mixed with air flowing thereto, and condenses to form inhalable aerosols, which is then carried towards the mouthpiece 640 and into the mouth of a user via the at least one fluid path 642. The air flowing into the mixing chamber 620 can flow from the at least one fluid path 642 and/or from the at least one fluid intake aperture 625 of the device 100.

[0244] According to some embodiments, the vaporization device of the present invention comprises a plurality of fluid control mechanisms disposed therein, selected from one or more of: mechanism 160, mechanism 260, mechanism 360, mechanism 460, mechanism 560, mechanism 660, mechanism 760, mechanism 860, and combinations thereof. Each possibility represents a different embodiment. For example, vaporization device 100 may comprise a combination of mechanisms 260 and 560, such that each transferring element is surrounded by a circumferential heating element 266 and a circumferential piezoelectric element 566, for providing a combined beneficial effect on the liquid disposed therein.

[0245] Reference is now made to Figure 13, illustrating a cross sectional side view of a liquid chamber 912 comprising a fluid control mechanism 960, according to some embodiments.

[0246] Fluid control mechanism 960 of Figure 13 is similar to fluid control mechanism 760 of Figure 11 A, and therefore share many common features as can be appreciated by the skilled in the art. Specific features or components are described below.

[0247] Thus, Figure 13 shows exemplary alternative implementations of some components of the fluid control mechanism. Specifically, fluid control mechanism 960 includes a plurality of transferring elements having cone-shaped portion.

[0248] According to some embodiments, the fluid control mechanism disposed within the vaporization device 600 is a fluid control mechanism 960.

[0249] According to some embodiments, the fluid control mechanism 960 comprises a plurality of transferring elements 965 and a plurality of corresponding flow inducing elements 963, wherein the liquid cartridge 610 comprises a plurality of liquid chambers 912, and wherein each transferring element 965 is fluidly coupled to a corresponding liquid chamber 912 at one end or surface thereof and to the mixing chamber 620 in the other end or surface thereof. [0250] According to some embodiments, at least some portions of each liquid chamber 912 are identical to at least some portions of each liquid chamber 712, as disclosed herein above. According to some embodiments, each liquid chamber 912 comprises a liquid chamber housing 913 accommodating therein the inner components of each liquid chamber 912. In further embodiments, each liquid chamber housing 913 is coupled to the cartridge housing 611. According to some embodiments, each liquid chamber housing 913 defines an inner surface 923, wherein said inner surface 923 defines a chamber inner space 922 configured to hold or contain a liquid composition 113 disposed therein, similarly to liquid chamber 712 as disclosed herein above.

[0251] According to some embodiments, each liquid chamber 912 comprises at least one transferring element 965 disposed therein, such that the liquid chamber 912 defines the chamber inner space 922 between the inner surface 923 thereof and the at least one transferring element 965, wherein the chamber inner space 922 is configured to contain a liquid composition 113 disposed therein. In some embodiments, the chamber inner space 922 of each liquid chamber 912 and the liquid composition 113 disposed therein surrounds or encompasses the transferring element 965.

[0252] According to some embodiments, each transferring element 965 extends from a first end 961 towards a second end 962 along a perpendicular axis 902 (extending through the center of each transferring element 965). In some embodiments, the first end 961 of each transferring element 965 is in fluid communication with the chamber inner space 922 of the liquid chamber 912. In some embodiments, the second end 962 of each transferring element 965 is in fluid communication with the mixing chamber 620 via a fluid outflow path 943C extending through a corresponding liquid chamber outlet 970 of each corresponding liquid chamber 912.

[0253] According to some embodiments, each transferring element 965 is in the form of an elongated tube or channel, or preferably a microchannel, optionally having similar shapes and/or dimensions as each transferring element 765, as disclosed herein above.

[0254] According to some embodiments, each transferring element 965 is a microchannel comprising a cone-shaped portion 964 (or edge) thereof, so that the cone-shaped portion 964 extends from an entry section 964A having an entry diameter D2 towards an exit section 964B having an exit diameter D3, wherein the exit diameter D3 is greater than the entry diameter D2. According to further embodiments, said entry diameter D2 is identical to the diameter of the microchannel at the first end 961 thereof. According to further embodiments, said exit section 964B having the exit diameter D3 defines the second end 962 of the transferring element 965.

[0255] In some embodiments, the second end 962 and/or the cone-shaped portion 964 of each transferring element 965 is directly or indirectly connected to at least one corresponding flow inducing element 963. In some embodiments, each flow inducing element 963 is embedded within or is surrounding the second end 962 and/or the cone-shaped portion 964 of each corresponding transferring element 965. In some embodiments, each flow inducing element 963 is a heating element 966, similar to heating element 766 as disclosed herein above. In further embodiments, each heating element 966 is shaped as a heating coil which is surrounding the second end 962 and/or the cone-shaped portion 964 of each transferring element 965.

[0256] According to some embodiments, each transferring element 965 or a portion thereof is at least partially circumferentially encompassed or enveloped or supported by one or more of a circumferential layer, a support structure element , a circumferential perforated shield, or a combination thereof, similar to those depicted in Figure 12, configured to couple or attach the transferring element 965 to the inner surface 923, in order to provide structural stability and integrity thereto (not shown).

[0257] According to some embodiments, it is suggested that the combination between the volume of each cone-shaped portion 964, defined by the entry diameter D2 and the exit diameter D3 thereof, and the amount of thermal energy applied from each corresponding at least one heating element 966 thereto, can define the amount vapor (i.e., “dose”) which is being transferred therethrough, from each corresponding liquid chamber 912 into the mixing chamber 620. Advantageously, said combination enables to control the dosage from each liquid chamber 912 which is transferred into the mixing chamber 620 and to form various vapors mixtures therein, and thus to maintain the entourage effect of various cannabinoids mixtures as disclosed herein above, similarly to the utilization of fluid control mechanism 160 featuring transferring element 165. Therefore, it should be understood that the utilization and purpose of the microchannel transferring element 965 are identical or similar to those of transferring element 165, as disclosed herein above.

[0258] According to some embodiments, the volume of each cone-shaped portion 964 is selected from the range of about 1 nanoliter - 100 microliters, preferably from about 20-200 nanoliters, or more preferably from about 10-100 nanoliters. It is contemplated, in some embodiments, that the volume of each cone-shaped portion 964 equals to half of a minimal dose from each liquid chamber 912.

[0259] According to some embodiments, activation of the fluid control mechanism 960 comprises the controller 650 sensing the inhalation by the user (via a sensor 632) and/or receives the user’s input and as a result activates the plurality of heating elements 966. The power source 630 supplies a pulse of energy to each heating element 966 to heat at least a portion of each cone-shaped portion 964 of each corresponding transferring element 965. The liquid disposed within each chamber inner space 922 of each liquid chamber 912 is wicked towards the first end 961 of each corresponding microchannel transferring element 965, onwards to the entry section having the entry diameter D2 of the cone-shaped portion 964 thereof, and then towards the exit section having the exit diameter D3 defining the second end 962 thereof.

[0260] Then, the liquid within each cone-shaped portion 964 is vaporized by the heating element 966, to create a heated vapor therein, which evaporates in the direction of the flow arrow 701 into the mixing chamber 620, along each fluid outflow path 943C via the corresponding liquid chamber outlet 970 of each corresponding liquid chamber 912. At the same time, the liquid being vaporized is replaced by further liquid moving towards the first end 761 of each transferring element 965 by capillary action.

[0261] According to some embodiments, the cone-shaped portion 964 of each transferring element 965 is directly or indirectly connected to at least one heating element 966 and is configured to receive heat therefrom, and to transfer said heat to the liquid disposed therein. Accordingly, heat is effectively transferred to the liquid disposed within the cone-shaped portion 964 of each transferring element 965 therethrough, so that excessive heat does not reach or affect the liquid disposed within the liquid chamber 912 and/or within the transferring element 965, thereby enabling to maintain a stable temperature range of the liquid composition(s) disposed within the liquid chamber.

[0262] According to some embodiments, upon the application of heat thereto, the liquid disposed within the cone-shaped portion 964 of each transferring element 965 evaporates from the exit section having the exit diameter D3 thereof, as disclosed herein above. Advantageously, it is contemplated that since the exit diameter D3 is greater than the entry diameter D2 of the cone-shaped portion 964 of each transferring element 965, it allows for a greater evaporation surface area of the liquid residing within portion 964, thereby enabling a more effective evaporation thereof.

[0263] According to some embodiments, the heated vapor of each transferring element 965 is transferred into the mixing chamber 620, to from a mixture of vapors, and then optionally mixed with air flowing thereto from the at least one fluid path 642 and/or from the at least one fluid intake aperture 625 of the device 600. In the mixing chamber 620, the vapor condenses to form an inhalable aerosol, which is carried towards the mouthpiece 640 and into the mouth of a user via the at least one fluid path 642.

[0264] Reference is now made to Figure 14, illustrating a method 1000 for providing customized mixtures of aerosols for inhalation, according to some embodiments.

[0265] According to another aspect, there is provided a method 1000 for providing customized mixtures of aerosols for inhalation by a user, the method comprising step 1010 of providing a vaporization device (e.g., vaporization device 100 or 600) as disclosed herein above.

[0266] According to some embodiments, the method 1000 further comprises step 1020 of selecting a liquid mixture formula via the user interaction portion (e.g., user interaction portion 136). According to some embodiments, the liquid mixture formulas of step 1020 can be predetermined, wherein the formulas of step 1020 are stored within the controller or are transferred thereto via an external computing device. According to other embodiments, the liquid mixture formulas of step 1020 can be custom made or programable according to input from the user and/or according to user variables (e.g., sex, weight, age, medical history, etc.).

[0267] According to some embodiments, the method 1000 further comprises step 1030 of actuating the fluid control mechanism (e.g., mechanisms 160-960), thereby producing energy by each flow inducing element (e.g., element 163, 467, 663, 763, 963) and applying it to a corresponding transferring element (e.g., elements 165, 365, 465, 665, 765, 865, or 965), according to the predetermined liquid mixture formula of step 1020.

[0268] According to some embodiments, the method 1000 further comprises step 1040 of forming a vapor mixture within the mixing chamber 120, wherein said vapor condenses to form an inhalable aerosol mixture therein.

[0269] According to some embodiments, step 1030 comprises facilitating flow of a predetermined dose of liquid drawn from each liquid chamber (e.g., liquid chamber 112) into the mixing chamber (e.g., mixing chamber 120), thereby forming a liquids mixture therein. In further such embodiments, step 1040 comprises actuating a heating element (e.g., heating element 169) disposed within the mixing chamber, thereby transforming the liquids mixture disposed therein into a vapor mixture.

[0270] According to alternative embodiments, step 1030 comprises facilitating flow of a predetermined dose of liquid drawn from each liquid chamber 112 into each corresponding transferring element as disclosed above, transforming said liquid into vapor therein, and transferring said vapor into the mixing chamber 120, thereby forming a vapor mixture therein.

[0271] According to some embodiments, step 1030 comprises actuating the fluid control mechanism as disclosed above, according to input received by the user via the user interaction portion (e.g., interaction portion 136) and/or according to inhalation by the user being detected by a sensor (e.g., sensor 132) configured to transfer data indicative thereof to the controller. In some embodiments, when the controller (e.g., controller 150) senses the user inhaling, it can initiate and/or adjust the amount of energy applied by each heating element to each corresponding transferring element, by controlling the activation of the power source and/or the power transfer therefrom to each heating element. [0272] According to some embodiments, the method 1000 further comprises step 1050 of inhaling the aerosol mixture of step 1040 via the mouthpiece 140 by the user.

[0273] As used herein, the term “plurality” means two or more.

[0274] As used herein, the term "about", when referring to a measurable value such as an amount, a temporal duration, and the like, is meant to encompass variations of +/-10%, more preferably +/-5%, even more preferably +/-1%, and still more preferably +/-0.1% from the specified value, as such variations are appropriate to perform the disclosed devices and/or methods.

Additional Examples of the Disclosed Technology

[0275] In view of the above-described implementations of the disclosed subject matter, this application discloses the additional examples enumerated below. It should be noted that one feature of an example in isolation or more than one feature of the example taken in combination and, optionally, in combination with one or more features of one or more further examples are further examples also falling within the disclosure of this application.

[0276] Example 1. A vaporization device comprising: a liquid cartridge chamber configured to accommodate a liquid cartridge comprising a plurality of liquid chambers therein, wherein each liquid chamber is configured to contain a liquid composition therein; a mixing chamber; a fluid control mechanism comprising a plurality of transferring elements and a plurality of flow inducing elements, wherein a first end or surface of each transferring element is in fluid communication with a corresponding liquid chamber, wherein a second end or surface of each transferring element is in fluid communication with the mixing chamber, and wherein at least a portion of each transferring element is directly or indirectly coupled to at least one corresponding flow inducing element; a mouthpiece comprising at least one fluid path extending from a ventilation end of the mouthpiece and the mixing chamber, wherein said at least one fluid path is configured to enable fluid communication therethrough; a controller configured to control production of energy by each flow inducing element applied to a corresponding transferring element, wherein the amount of energy is configured to facilitate flow of a predetermined dose of liquid drawn from each liquid chamber or to transform said liquid into vapor, and a power source chamber configured to accommodate at least one power source disposed therein for providing power at least to the controller and the plurality of flow inducing elements.

[0277] Example 2. The device of any example herein, particularly example 1, wherein the power source chamber comprises at least one power source disposed therein.

[0278] Example 3. The device of any example herein, particularly any one of examples 1 to

2, wherein the liquid cartridge is configured to be detachably attached from the liquid cartridge chamber, and wherein each liquid chamber comprises a liquid composition disposed therein.

[0279] Example 4. The device of any example herein, particularly any one of examples 1 to

3, wherein the liquid composition comprises one or more materials selected from the group consisting of: tobacco, nicotine, caffeine, essential oil, cannabis extract, water, flavoring material, an aerosol former substance, and combinations thereof.

[0280] Example 5. The device of any example herein, particularly example 4, wherein the cannabis extract comprises one or more materials selected from the group consisting of: cannabinoids, terpenes, terpenoids, flavonoids, nitrogenous compounds, amino acids, proteins, glycoproteins, sugars, hydrocarbons, fatty acids, esters, lactones, steroids, non-cannabinoid phenols, and combinations thereof.

[0281] Example 6. The device of any example herein, particularly any one of examples 1 to 5, wherein each liquid chamber comprises a different liquid composition disposed therein, and wherein each liquid composition comprises at least one strand of cannabinoid or a combination of different strands of cannabinoids.

[0282] Example 7. The device of any example herein, particularly any one of examples 1 to

6, wherein each transferring element is configured to enable fluid flow therethrough, and thus to enable fluid communication between each liquid chamber and the mixing chamber.

[0283] Example 8. The device of any example herein, particularly any one of examples 1 to

7, wherein each flow inducing element is circumferentially surrounding at least a portion of each transferring element, or wherein each flow inducing element is integrated or embedded within at least a portion of each transferring element.

[0284] Example 9. The device of any example herein, particularly any one of examples 1 to

8, wherein each transferring element has a volume selected from the range of about 1 nanoliter - 100 microliters.

[0285] Example 10. The device of any example herein, particularly example 9, wherein the volume of each transferring element is selected from the range of about 1 - 1000 nanoliters.

[0286] Example 11. The device of any example herein, particularly example 10, wherein the volume of each transferring element is selected from the range of about 20 - 200 nanoliters.

[0287] Example 12. The device of any example herein, particularly any one of examples 1 to

11, wherein the mixing chamber comprises a heating element disposed therein, said heating element is configured to receive power from the at least one power source and is operatively connected to the controller.

[0288] Example 13. The device of any example herein, particularly any one of examples 1 to

12, further comprising a user interaction portion in operative communication with the controller, wherein the user interaction portion is configured to provide to the controller signals indicative of the amount of energy to be applied to each transferring element, preferably based on input received by the user. [0289] Example 14. The device of any example herein, particularly example 13, wherein the controller is configured to adjust the amount of energy applied to each transferring element according to one or more predetermined liquid mixture formulas stored therein, and/or according to input received by the user via the user interaction portion.

[0290] Example 15. The device of any example herein, particularly any one of examples 1 to

14, further comprising at least one communication device capable of connecting to an external computing device through a wired or wireless connection.

[0291] Example 16. The device of any example herein, particularly any one of examples 1 to

15, wherein each flow inducing element is a heating element configured to produce thermal energy, and thereby to apply thermal energy to each corresponding wicking element.

[0292] Example 17. The device of any example herein, particularly example 16, wherein each liquid chamber or portions thereof comprises an insulating material or layer, configured to prevent or reduce thermal affects from affecting the temperature of the liquids disposed therein.

[0293] Example 18. The device of any example herein, particularly any one of examples 16 to 17, wherein each heating element is in the form of a heating coil, or wherein each heating element is U-shaped and is at least partially surrounding or enveloping each transferring element.

[0294] Example 19. The device of any example herein, particularly any one of examples 1 to 18, wherein each transferring element is an elongated rigid microchannel.

[0295] Example 20. The device of any example herein, particularly any one of examples 1 to 18, wherein each transferring element is a porous material and comprises an interconnected porous inner volume, wherein said inner volume is selected from the range of about 1 nanoliter - 100 microliters.

[0296] Example 21. The device of any example herein, particularly any one of examples 1 to 20, wherein each flow inducing element is a piezoelectric element configured to produce vibration energy, wherein each transferring element is an elongated fluid conduit or a microchannel made from a resilient flexible material, wherein upon actuation said piezoelectric element transmits vibration energy to each corresponding transferring element, thus causing the transferring element to be repeatedly displaced inwards, thereby facilitating the formation of and/or transferring liquid droplets from each corresponding transferring element into the mixing chamber.

[0297] Example 22. The device of any example herein, particularly any one of examples 1 to 21, wherein the liquid cartridge comprises: a cartridge housing accommodating therein the plurality of liquid chambers, wherein the cartridge housing comprises a plurality of fluid intake apertures configured to facilitate fluid communication between an external environment of the device and each liquid chamber and/or the mixing chamber; the fluid control mechanism comprising the plurality of transferring elements and the plurality of corresponding flow inducing elements; and the mixing chamber, wherein the mixing chamber is fluidly coupled to each liquid chamber, and wherein the mixing chamber comprises a mixing chamber exit configured to enable fluid flow therefrom and into at least a portion of the at least one fluid path of the mouthpiece.

[0298] Example 23. The device of any example herein, particularly example 22, wherein the liquid cartridge comprises a cartridge electrical connector configured to receive power from the at least one power source and to transfer it to a power management component disposed therein, wherein said power management component is configured to transfer power to each liquid chamber, and wherein each liquid chamber comprises a power contact configured to receive power from the power management component and to transfer it to the corresponding flow inducing element.

[0299] Example 24. The device of any example herein, particularly any one of examples 22 to 23, wherein each liquid chamber comprises: a liquid chamber outlet fluidly coupled to the mixing chamber; a liquid chamber housing coupled (or optionally detachably attached) to the cartridge housing, wherein said liquid chamber housing defines an inner surface; at least one transferring element of the plurality of transferring elements coupled to at least one corresponding flow inducing element of the plurality of flow inducing elements, such that the liquid chamber defines a chamber inner space between the inner surface of the liquid chamber housing and the at least one transferring element, wherein the chamber inner space is configured to contain a liquid composition disposed therein; wherein the chamber inner space is in fluid communication with the at least one transferring element, and wherein the at least one transferring element is configured to allow liquid flow from the chamber inner space therethrough and toward the liquid chamber outlet.

[0300] Example 25. The device of any example herein, particularly example 24, wherein each liquid chamber further comprises a liquid chamber inlet in fluid communication with at least one of the plurality of fluid intake apertures of the cartridge housing.

[0301] Example 26. The device of any example herein, particularly example 25, wherein each at least one transferring element comprises a middle portion extending between an outer first surface and an inner second surface, wherein the first surface is in fluid communication with the chamber inner space of the liquid chamber, wherein the second surface defines a fluid inner path extending therethrough which is in fluid communication with the mixing chamber via the liquid chamber outlet, wherein the fluid inner path is further in fluid communication with the liquid chamber inlet, and wherein each flow inducing element is embedded or integrated within the middle portion or is coupled to the outer first surface or the inner second surface of each transferring element.

[0302] Example 27. The device of any example herein, particularly example 26, wherein each transferring element is shaped as a porous cylinder comprising an interconnected porous inner volume extending between the outer first surface and the inner second surface, wherein said inner volume is selected from the range of about 1 nanoliter - 100 microliters. [0303] Example 28. The device of any example herein, particularly any one of examples 26 to 27, wherein each flow inducing element is a heating element configured to produce thermal energy, and thereby to apply thermal energy to each corresponding transferring element.

[0304] Example 29. The device of any example herein, particularly example 28, wherein the heating element is a heating coil.

[0305] Example 30. The device of any example herein, particularly any one of examples 26 to 29, wherein the first surface of each transferring element is at least partially surrounded by a wicking circumferential layer configured to enable fluid communication therethrough, wherein said wicking circumferential layer is at least partially surrounded by a circumferential perforated shield comprising a plurality of apertures configured to enable fluid communication therethrough towards the circumferential layer.

[0306] Example 31. The device of any example herein, particularly example 24, wherein each transferring element is a microchannel extending from a first end towards a second end and defines a lumen extending therebetween, wherein the first end is in fluid communication with the chamber inner space of the liquid chamber, and wherein the second end thereof is in fluid communication with the mixing chamber via the liquid chamber outlet.

[0307] Example 32. The device of any example herein, particularly example 31, wherein within each liquid chamber the at least one flow inducing element is at least partially surrounded by a corresponding circumferential layer, and wherein said circumferential layer and at least a portion of the at least one transferring element are surrounded and supported by a corresponding support structure element.

[0308] Example 33. The device of any example herein, particularly example 32, wherein said support structure element is at least partially surrounded by a circumferential perforated shield comprising a plurality of apertures configured to enable fluid communication therethrough towards the first end of the at least one transferring element. [0309] Example 34. The device of any example herein, particularly any one of examples 31 to 33, wherein each flow inducing element is a heating element surrounding or enveloping at least a portion of each corresponding transferring element.

[0310] Example 35. The device of any example herein, particularly example 34, wherein each circumferential layer is an insulating layer configured to prevent or reduce the amount of thermal energy generated by each heating element and directed towards the liquid disposed within the liquid chamber.

[0311] Example 36. The device of any example herein, particularly any one of examples 31 to 33, wherein each flow inducing element is a piezoelectric element configured to produce vibration energy and is surrounding or enveloping at least a portion of each transferring element.

[0312] Example 37. The device of any example herein, particularly any one of examples 31 to 36, wherein the cartridge housing further comprises at least one fluid inflow path configured to facilitate fluid communication therethrough between at least one of the plurality of fluid intake apertures of the cartridge housing and the mixing chamber.

[0313] Example 38. The device of any example herein, particularly any one of examples 1 to 37, for use in providing customized mixtures of aerosols for inhalation by a user, preferably for use in treating or suppressing a disease or a disorder selected from the group consisting of cancer, chronic pain, migraine, and a combination thereof.

[0314] Example 39. A method for providing customized mixtures of aerosols for inhalation by a user, the method comprising:

(a) providing the vaporization device of any example herein, particularly any one of examples 1 to 37;

(b) selecting a liquid mixture formula via the user interaction portion; (c) actuating the fluid control mechanism, thereby producing energy by each flow inducing element and applying it to a corresponding transferring element, according to the predetermined liquid mixture formula of step (b); and

(d) forming a vapor mixture within the mixing chamber, wherein said vapor condenses to form an inhalable aerosol mixture therein.

[0315] Example 40. The method of any example herein, particularly example 39, wherein the formula of step (b) is stored within the controller or is transferred thereto via a communication device.

[0316] Example 41. The method of any example herein, particularly any one of examples 39 to 40, wherein step (c) comprises facilitating flow of a predetermined dose of liquid drawn from each liquid chamber into the mixing chamber, thereby forming a liquids mixture therein.

[0317] Example 42. The method of any example herein, particularly example 41, wherein step (d) comprises actuating a heating element disposed within the mixing chamber, thereby transforming the liquids mixture disposed therein into a vapor mixture.

[0318] Example 43. The method of any example herein, particularly any one of examples 39 to 40, wherein step (c) comprises facilitating flow of a predetermined dose of liquid drawn from each liquid chamber into each corresponding transferring element, transforming said liquid into vapor therein, and transferring said vapor into the mixing chamber, thereby forming a vapor mixture therein.

[0319] Example 44. The method of any example herein, particularly any one of examples 39 to 43, wherein step (c) comprises actuating the fluid control mechanism: upon receiving input from the user via the user interaction portion, upon sensing an inhalation by the user detected by a sensor configured to transfer data indicative thereof to the controller, or both.

[0320] Example 45. A method for treating or suppressing a disease or a disorder selected from the group consisting of cancer, chronic pain, migraine, and a combination thereof, wherein the method comprises providing customized mixtures of aerosols for inhalation by a user in need thereof according to any example herein, particularly the method of any one of examples 39 to 44.

[0321] Example 46. A liquid cartridge configured to be detachably attached to a vaporization device, the liquid cartridge comprising: a cartridge housing accommodating therein a plurality of liquid chambers, wherein each liquid chamber comprises: a liquid chamber outlet configured to be fluidly coupled to a mixing chamber, a liquid chamber housing coupled to the cartridge housing, wherein said liquid chamber housing is defining an inner surface, at least one transferring element coupled to at least one corresponding flow inducing element, wherein the transferring element and corresponding flow inducing element are disposed within the liquid chamber, such that the liquid chamber defines a chamber inner space between the inner surface and the transferring element, wherein the chamber inner space is configured to contain a liquid composition disposed therein, and wherein the chamber inner space is in fluid communication with the transferring element, and wherein the transferring element is configured to allow liquid flow from the chamber inner space therethrough and toward the liquid chamber outlet, a mixing chamber, wherein the mixing chamber is fluidly coupled to each liquid chamber, and wherein the mixing chamber comprises a mixing chamber exit configured to enable fluid flow therefrom and into a portion of the vaporization device when attached thereto; and wherein the cartridge housing comprises a plurality of fluid intake apertures configured to facilitate fluid communication between an external environment of the device and each liquid chamber and/or the mixing chamber. [0322] Example 47. The cartridge of any example herein, particularly example 46, further comprising a cartridge electrical connector configured to receive power from a power source and to transfer it to a power management component disposed therein, wherein said power management component is configured to transfer power to each liquid chamber, and wherein each liquid chamber comprises a power contact configured to receive power from the power management component and to transfer it to the corresponding flow inducing element.

[0323] Example 48. The cartridge of any example herein, particularly any one of examples 46 to 47, each transferring element has a volume selected from the range of about 1 nanoliter - 100 microliters.

[0324] Example 49. The cartridge of any example herein, particularly any one of examples 46 to 48, wherein each liquid chamber further comprises a liquid chamber inlet in fluid communication with at least one of the plurality of fluid intake apertures of the cartridge housing.

[0325] Example 50. The cartridge of any example herein, particularly example 49, wherein each transferring element comprises a middle portion extending between an outer first surface and an inner second surface, wherein the first surface is in fluid communication with the chamber inner space of the liquid chamber, wherein the second surface defines a fluid inner path extending therethrough which is in fluid communication with the mixing chamber via the liquid chamber outlet, wherein the fluid inner path is further in fluid communication with the liquid chamber inlet, and wherein each flow inducing element is a heating element embedded or integrated within the middle portion or coupled to the outer first surface or the inner second surface of each transferring element.

[0326] Example 51. The cartridge of any example herein, particularly example 50, wherein each transferring element is shaped as a porous cylinder comprising an interconnected porous inner volume extending between the outer first surface and the inner second surface, wherein said inner volume is selected from the range of about 1 nanoliter - 100 microliters.

[0327] Example 52. The cartridge of any example herein, particularly any one of examples 50 to 51, wherein the first surface of each transferring element is at least partially surrounded by a wicking circumferential layer configured to enable fluid communication therethrough, wherein said wicking circumferential layer is at least partially surrounded by a circumferential perforated shield comprising a plurality of apertures configured to enable fluid communication therethrough towards the wicking circumferential layer.

[0328] Example 53. The cartridge of any example herein, particularly any one of examples 46 to 48, wherein each transferring element is a microchannel extending from a first end towards a second end and defines a lumen extending therebetween, wherein the first end is in fluid communication with the chamber inner space of the liquid chamber, and wherein the second end thereof is in fluid communication with the mixing chamber via the liquid chamber outlet.

[0329] Example 54. The cartridge of any example herein, particularly example 53, wherein within each liquid chamber the at least one flow inducing element is at least partially surrounded by a corresponding circumferential layer, and wherein said circumferential layer and at least a portion of the at least one transferring element are surrounded and supported by a corresponding support structure element.

[0330] Example 55. The cartridge of any example herein, particularly example 54, wherein said support structure element is at least partially surrounded by a circumferential perforated shield comprising a plurality of apertures configured to enable fluid communication therethrough towards the first end of the at least one transferring element.

[0331] Example 56. The cartridge of any example herein, particularly any one of examples 53 to 55, wherein each flow inducing element is a heating element surrounding or enveloping at least a portion of each corresponding transferring element.

[0332] Example 57. The cartridge of any example herein, particularly example 56, wherein each circumferential layer is an insulating layer configured to prevent or reduce the amount of thermal energy generated by each heating element and directed towards the liquid disposed within the liquid chamber. [0333] Example 58. The cartridge of any example herein, particularly any one of examples 53 to 55, wherein each flow inducing element is a piezoelectric element configured to produce vibration energy and is surrounding or enveloping at least a portion of each transferring element.

[0334] Example 59. The cartridge of any example herein, particularly any one of examples 53 to 58, wherein the cartridge housing further comprises at least one fluid inflow path configured to facilitate fluid communication therethrough between at least one of the plurality of fluid intake apertures of the cartridge housing and the mixing chamber.

[0335] Example 60. The device of any example herein, particularly example 31, or the cartridge of any example herein, particularly example 53, wherein each transferring element comprises a cone-shaped portion extending from an entry section having an entry diameter D2 towards an exit section having an exit diameter D3, wherein the exit diameter D3 is greater than the entry diameter D2, wherein the entry diameter D2 is identical to the diameter of the microchannel at the first end thereof, wherein the exit section having the exit diameter D3 defines the second end of the transferring element, and wherein the second end and/or the cone- shaped portion of each transferring element is directly or indirectly connected to the corresponding flow inducing element.

[0336] It is appreciated that certain features of the invention, which are, for clarity, described in the context of separate embodiments, may also be provided in combination in a single embodiment. Conversely, various features of the invention, which are, for brevity, described in the context of a single embodiment, may also be provided separately or in any suitable subcombination or as suitable in any other described embodiment of the invention. No feature described in the context of an embodiment is to be considered an essential feature of that embodiment, unless explicitly specified as such.

[0337] Although the invention is described in conjunction with specific embodiments thereof, it is evident that numerous alternatives, modifications and variations that are apparent to those skilled in the art may exist. It is to be understood that the invention is not necessarily limited in its application to the details of construction and the arrangement of the components and/or methods set forth herein. Other embodiments may be practiced, and an embodiment may be carried out in various ways. Accordingly, the invention embraces all such alternatives, modifications and variations that fall within the scope of the appended claims.